| Andre Miguel Valente Silva | AC Milan | 01-07-2017 | 38M € |
| Diogo Jose Teixeira da Silva | Atletico Madrid | 01-07-2017 | Unknown |
| I. Díaz | Deportivo La Coruna | 22-09-2017 | Unknown |
| Rui Sousa | Boavista | 31-08-2017 | Loan |
| Raul Manolo Gudino Vega | Apoel | 31-08-2017 | Loan |
| Joao Carlos Vilaca Teixeira | Braga | 31-08-2017 | Loan |
| O. Abou | Majadahonda | 30-08-2017 | Unknown |
| Abdoulaye Ba | Rayo Vallecano | 30-08-2017 | Free |
| Hyun-Jun Suk | Troyes | 30-08-2017 | Loan |
| Victor Hugo Garcia Hernandez | Vitoria Guimaraes | 28-08-2017 | Unknown |
| Josué | Osmanlispor | 25-08-2017 | Unknown |
| Graça | Feirense | 24-08-2017 | Unknown |
| Luis Rafael Soares Alves | Fulham | 22-08-2017 | Loan |
| Bruno Martins Indi | Stoke City | 11-08-2017 | 7.7M € |
| Adrian Lopez Alvarez | Deportivo La Coruna | 11-08-2017 | Loan |
| Jose Manuel Silva Oliveira | Wisla | 09-08-2017 | Loan |
| Mikel Ndubusi Agu | Bursaspor | 07-08-2017 | Loan |
| Fernando Manuel Ferreira Fonseca | Estoril Praia | 06-08-2017 | Loan |
| Leandro Miguel Pereira Da Silva | AEL | 25-07-2017 | Unknown |
| Goncalo Mendes Paciencia | Vitoria Setubal | 20-07-2017 | Loan |
| Diogo Sousa Verdasca | Real Zaragoza | 17-07-2017 | Unknown |
| S. Bolat | Antwerp | 17-07-2017 | Unknown |
| Gleison Wilson Da Silva Moreira | Penafiel | 15-07-2017 | Loan |
| José Ángel | Eibar | 14-07-2017 | Free |
| Fali Candé | Benfica | 10-07-2017 | Unknown |
| Ruben Diogo Da Silva Neves | Wolves | 08-07-2017 | 17M € |
| Willy Boly | Wolves | 08-07-2017 | Loan |
| Chidozie Collins Awaziem | Nantes | 05-07-2017 | Loan |
| Sami | Aves | 03-07-2017 | Unknown |
| Inácio | Portimonense | 02-07-2017 | Loan |
| Ivo Rodrigues | Antwerp | 02-07-2017 | Loan |
| Francisco Augusto Neto Ramos | Vitoria Guimaraes | 02-07-2017 | Unknown |
| I. Lichnovsky | Necaxa | 02-07-2017 | $2M |
| Raúl Almeida | Pacos Ferreira | 01-07-2017 | Unknown |
| Joris Kayembe Ditu | Nantes | 01-07-2017 | Unknown |
| Pité | Tondela | 01-07-2017 | Unknown |
| O. Govea | Mouscron | 01-07-2017 | Loan |
| Rui Manuel Linhares Areias | Vitoria Guimaraes | 01-07-2017 | Unknown |
| Mauro Andres Caballero Aguilera | San Luis | 01-07-2017 | Loan |
| Tomas Martins Podstawski | Vitoria Setubal | 01-07-2017 | Unknown |
| Tiago Filipe Sousa Nobrega Rodrigues | CSKA Moscow | 01-07-2017 | Unknown |
| Andres Eduardo Fernandez Moreno | Villarreal | 01-07-2017 | 2M € |
| Ricardo Nunes | Chaves | 01-07-2017 | Unknown |
| L. Depoitre | Huddersfield Town | 24-06-2017 | 5M € |
| Idrisa Sambú | Spartak Moscow | 23-02-2017 | 1M € |
| Sami | Arouca | 17-02-2017 | Unknown |
| Hyun-Jun Suk | Debrecen | 13-02-2017 | Loan |
| Rodrigo Alves | Chaves | 10-02-2017 | Unknown |
| H. Chikhaoui | Varzim | 01-02-2017 | Loan |
| Kelvin | Vasco da Gama | 31-01-2017 | Loan |
| Sergio Miguel Relvas de Oliveira | Nantes | 31-01-2017 | Loan |
| Bueno | Leganés | 31-01-2017 | Loan |
| S. Bolat | Arouca | 31-01-2017 | Loan |
| Gleison Wilson Da Silva Moreira | Portimonense | 26-01-2017 | Loan |
| Luís Mata | Portimonense | 26-01-2017 | Loan |
| Abdoulaye Ba | 1860 Munich | 24-01-2017 | Loan |
| Ronan | Tombense | 23-01-2017 | Unknown |
| Adrian Lopez Alvarez | Villarreal | 21-01-2017 | Loan |
| Silvestre Varela | FC Porto | 20-01-2017 | 500K € |
| Leandro Miguel Pereira Da Silva | Academica Coimbra | 17-01-2017 | Loan |
| Evandro Goebel | Hull City | 13-01-2017 | Unknown |
| Goncalo Mendes Paciencia | Rio Ave | 07-01-2017 | Loan |
| Mauro Andres Caballero Aguilera | Palestino | 01-01-2017 | Loan |
| Tiago Filipe Sousa Nobrega Rodrigues | CSKA Sofia | 01-07-2017 | Unknown |
| Jose Manuel Silva Oliveira | Wisla Krakow | 09-08-2017 | Loan |
| Chidozie Collins Awaziem | Porto II | 01-07-2018 | Unknown |
| S. Irala | Rubio Nu | 01-07-2018 | Unknown |
| Rúben Macedo | Varzim | 04-01-2018 | Loan |
| Bueno | Malaga | 09-01-2018 | Loan |
| A. Waris | Lorient | 01-07-2018 | Unknown |
| Juan Fernando Quintero Paniagua | River Plate | 24-01-2018 | Loan |
| Miguel Arturo Layun Prado | Sevilla | 29-01-2018 | Loan |
| Wenderson Rodrigues do Nascimento Galeno | Portimonense | 23-01-2018 | Loan |
| F. Varela | Portimonense | 23-01-2018 | Loan |
| Paulo Henrique Soares dos Santos | Portimonense | 30-06-2018 | Unknown |
| Joao Paulo Santos da Costa | Gil Vicente | 22-01-2018 | Loan |
| Andre Filipe Ferreira Coelho Pereira | Vitoria Setubal | 31-01-2018 | Loan |
| Luis Rafael Soares Alves | Portimonense | 31-01-2018 | Unknown |
| Y. Osorio | Tondela | 01-07-2018 | Unknown |
| Walter Henrique Da Silva | Paysandu | 01-02-2018 | Loan |
| Chiderah Ezeh | Portimonense | 01-07-2018 | Unknown |
| Jorge Filipe Oliveira Fernandes | Tondela | 31-01-2018 | Loan |
| Jose Manuel Silva Oliveira | Feirense | 31-01-2018 | Loan |
| Walter | CSA | 14-04-2018 | Loan |
| Ricardo Domingos Barbosa Pereira | Leicester City | 09-06-2018 | 25M € |
| Ivan Marcano Sierra | Roma | 01-07-2018 | Unknown |
| Jose Diogo Dalot Teixeira | Man Utd | 08-06-2018 | Unknown |
| Raul Manolo Gudino Vega | Chivas Guadalajara | 01-07-2018 | Unknown |
| Yordan Hernando Osorio Paredes | Vitoria Guimaraes | 03-07-2018 | Loan |
| Goncalo Mendes Paciencia | Eintracht Frankfurt | 12-07-2018 | 3M € |
| Miguel Arturo Layun Prado | Villarreal | 11-07-2018 | 3.6M € |
| Wenderson Rodrigues do Nascimento Galeno | Rio Ave | 11-07-2018 | Loan |
| Joao Carlos Vilaca Teixeira | Vitoria Guimaraes | 26-07-2018 | Free |
| Ewerton da Silva Pereira | Portimonense | 24-07-2018 | Loan |
| Jose Manuel Silva Oliveira | Santa Clara | 05-07-2018 | Unknown |
| Andre Filipe Bras Andre | Vitoria Guimaraes | 04-07-2018 | Free |
| Abdul Majeed Waris | Nantes | 07-08-2018 | Loan |
| Diego Antonio Reyes Rosales | Fenerbahce | 25-08-2018 | Free |
| O. Govea | Antwerp | 16-08-2018 | Unknown |
| Joao Paulo Santos da Costa | Cartagena | 05-08-2018 | Loan |
| Saidy Janko | Nottingham Forest | 31-08-2018 | Loan |
| Jose Pedro Malheiro de Sa | Olympiakos | 31-08-2018 | Unknown |
| Mikel Ndubusi Agu | Vitoria Setubal | 31-08-2018 | Loan |
| Danúbio | G Anapolis | 30-06-2018 | Unknown |
| S. Vera | River Plate | 01-07-2018 | Unknown |
| Mauro Andres Caballero Aguilera | Española | 01-01-2019 | Free |
| Ewerton da Silva Pereira | Urawa Red Diamonds | 12-01-2019 | Loan |
| Rúben Macedo | Chaves | 02-01-2019 | Unknown |
| Inácio | Guarani | 01-01-2019 | Loan |
| Chidozie Collins Awaziem | Rize | 22-01-2019 | Loan |
| Moreto Cassamã | Reims | 30-01-2019 | Unknown |
| Mauro Andres Caballero Aguilera | Union Espanola | 14-01-2019 | Free |
| Sergio Miguel Relvas de Oliveira | PAOK | 31-01-2019 | Loan |
| M. Ndiaye | Braga | 01-07-2019 | Unknown |
| Rui Pedro da Silva e Sousa | Varzim | 30-01-2019 | Loan |
| J. Maleck | Sevilla | 03-01-2019 | Unknown |
| Kelvin | Fluminense | 23-04-2019 | Unknown |
| Felipe Augusto de Almeida Monteiro | Atletico Madrid | 01-07-2019 | 20M € |
| Jorge Fernandes | Kasimpasa | 14-06-2019 | Loan |
| Éder Militão | Real Madrid | 01-07-2019 | 50M € |
| Hector Miguel Herrera Lopez | Atletico Madrid | 03-07-2019 | Unknown |
| Federico Nicolas Varela | Leganes | 04-07-2019 | Unknown |
| Oliver Torres Munoz | Sevilla | 15-07-2019 | € 12M |
| Rui Pedro Silva Costa | Alcorcon | 06-07-2019 | Loan |
| Saidy Janko | BSC Young Boys | 01-07-2019 | Loan |
| O. Govea | Zulte Waregem | 09-07-2019 | Unknown |
| Andre Filipe Ferreira Coelho Pereira | Vitoria Guimaraes | 22-07-2019 | Loan |
| Mikel Ndubusi Agu | Vitoria Guimaraes | 18-07-2019 | Free |
| O. Govea | ZW | 09-07-2019 | Unknown |
| Yacine Brahimi | Rayyan | 22-07-2019 | Unknown |
| Adrian Lopez Alvarez | Osasuna | 30-07-2019 | Free |
| João Pedro | Bahia | 31-07-2019 | Loan |
| Inácio | Penafiel | 31-07-2019 | Loan |
| Wenderson Rodrigues do Nascimento Galeno | Braga | 02-07-2019 | Unknown |
| Fernando Andrade dos Santos | Sivasspor | 09-08-2019 | Loan |
| Chidozie Collins Awaziem | Leganes | 15-08-2019 | Loan |
| Rui Pedro da Silva e Sousa | Granada | 18-08-2019 | Loan |
| Diogo Queirós | Mouscron | 27-08-2019 | Loan |
| Yordan Hernando Osorio Paredes | Zenit St Petersburg | 31-08-2019 | Loan |
| Vanailson Luciano de Souza Alves | Famalicão | 01-09-2019 | Loan |
| Fabiano Ribeiro de Freitas | Omonia Nicosia | 17-10-2019 | Unknown |
| Andre Filipe Ferreira Coelho Pereira | Real Zaragoza | 10-01-2020 | Loan |
| Abdul Majeed Waris | Strasbourg | 17-01-2020 | Loan |
| R. Saravia | SC Internacional | 03-03-2020 | Unknown |
| Kristian Dobrev | Botev Plovdiv | 08-06-2020 | Unknown |
| Fábio Silva | Wolves | 05-09-2020 | € 40M |
| Vitinha | Wolves | 09-09-2020 | Loan |
| Chidozie Collins Awaziem | Boavista | 05-09-2020 | Loan |
| Andre Filipe Ferreira Coelho Pereira | Rio Ave | 01-09-2020 | Unknown |
| Vincent Pate Aboubakar | Besiktas | 25-09-2020 | Unknown |
| Francisco das Chagas Soares dos Santos | Tianjin Teda | 30-09-2020 | Unknown |
| Danilo Luis Helio Pereira | PSG | 05-10-2020 | Loan |
| Alex Nicolao Telles | Man Utd | 05-10-2020 | € 15M |
| Tomás Esteves | Reading | 05-10-2020 | Loan |
| Yordan Hernando Osorio Paredes | Parma | 05-10-2020 | € Unknown |
| Diogo Queirós | Famalicão | 06-10-2020 | Free |
| Jose Luis Mendes Andrade | Lokomotiv Moscow | 06-10-2020 | € 7M |
| Fernando Andrade dos Santos | Rize | 02-10-2020 | Loan |
| Rui Pedro Silva Costa | Deportivo La Coruna | 18-09-2020 | Unknown |
| Victorio Maximiliano Pereira Paez | Penarol | 01-02-2021 | Free |
| Shoya Nakajima | Al-Ain | 16-01-2021 | Loan |
| Moussa Marega | Hilal | 01-07-2021 | Free |
| Manuel Mané | AEL | 01-07-2021 | Unknown |
| M. Loum | Alaves | 23-07-2021 | Loan |
| M. Mbaye | Viseu | 27-07-2021 | Free |
| Rafael Pereira | Vitoria Guimaraes | 07-07-2021 | Unknown |
| Fernando Andrade dos Santos | Feiha | 01-08-2021 | Loan |
| Rui Filipe Caetano Moura | Belenenses | 24-08-2021 | Loan |
| Rodrigo Valente | Estoril Praia | 31-08-2021 | Loan |
| Romário Baró | Estoril Praia | 31-08-2021 | Loan |
| João Pedro | Corinthians | 25-08-2021 | Loan |
| Eulanio Angelo Chipela Gomes | FC Dallas | 10-01-2022 | Loan |
| Sergio Miguel Relvas de Oliveira | Roma | 12-01-2022 | Loan |
| Jesus Manuel Corona Ruiz | Sevilla | 14-01-2022 | € 3M |
| L. Díaz | Liverpool | 30-01-2022 | € 44.5M |
| R. Saravia | Botafogo | 15-03-2022 | Free |
| Fábio Vieira | Arsenal | 17-06-2022 | € 35M |
| Vitinha | PSG | 01-07-2022 | Unknown |
| Sergio Miguel Relvas de Oliveira | Galatasaray | 09-07-2022 | € 3M |
| Chancel Mbemba Mangulu | Marseille | 15-07-2022 | Free |
| Diogo Leite | 1.FC Union Berlin | 16-07-2022 | Loan |
| Francisco Conceição | Ajax | 21-07-2022 | Unknown |
| M. Ndiaye | Estoril Praia | 25-07-2022 | Unknown |
| M. Loum | Reading | 29-07-2022 | Loan |
| Rui Filipe Caetano Moura | Gil Vicente | 27-07-2022 | Loan |
| Tomás Esteves | Pisa | 02-08-2022 | Loan |
| A. Marchesín | Celta Vigo | 01-08-2022 | Unknown |
| Romário Baró | Casa Pia | 23-08-2022 | Loan |
| Eulanio Angelo Chipela Gomes | Santa Clara | 31-01-2023 | Loan |
| Fernando Andrade dos Santos | Casa Pia | 01-07-2023 | Free |
| M. Uribe | Sadd | 01-07-2023 | Free |
| Eulanio Angelo Chipela Gomes | Samsunspor | 11-07-2023 | Unknown |
| João Marcelo | Cruzeiro | 01-08-2023 | Loan |
| Wilson Migueis Manafa Janco | Granada | 07-08-2023 | Free |
| M. Loum | Raed | 10-08-2023 | Free |
| Rodrigo Conceição | FC Zurich | 17-08-2023 | Free |
| Otavio Edmilson da Silva Monteiro | Nassr | 22-08-2023 | € 60M |
| Bruno Xavier Almeida Costa | Valenciennes | 01-09-2023 | Unknown |
| Gabriel Veron | Cruzeiro | 11-01-2024 | Loan |
| Fran Navarro | Olympiakos | 01-01-2024 | Loan |
| David Carmo | Olympiakos | 26-01-2024 | Loan |
| Nilton Varela | Estrela | 30-01-2024 | Unknown |
| Ussumane Djaló | Southampton | 01-02-2024 | Loan |