This page lists the head-to-head record of Panathinaikos vs Xanthi including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Xanthi | Panathinaikos | Draws |
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| Total Matches | 57 | 14 | 33 | 10 |
| At Skoda Xanthi Arena | 29 | 7 | 18 | 4 |
| At Olympic Stadium | 28 | 7 | 15 | 6 |
| Super League Matches | 53 | 13 | 32 | 8 |
| Cup Matches | 4 | 1 | 1 | 2 |
| Total Goals Scored | 139 | 52 | 87 | |
Last 50 Xanthi vs Panathinaikos Matches
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| 2020 19 January | | Super League | Xanthi FC | 0 - 1 | Panathinaikos |
| 2019 5 October | | Super League | Panathinaikos | 0 - 1 | Xanthi FC |
| 2019 13 January | | Super League | Panathinaikos | 2 - 2 | Xanthi FC |
| 2018 26 August | | Super League | Xanthi FC | 0 - 1 | Panathinaikos |
| 2018 7 May | | Super League | Panathinaikos | 1 - 2 | Xanthi FC |
| 2017 17 December | | Super League | Xanthi FC | 1 - 1 | Panathinaikos |
| 2017 25 February | | Super League | Xanthi FC | 1 - 0 | Panathinaikos |
| 2016 16 October | | Super League | Panathinaikos | 1 - 2 | Xanthi FC |
| 2016 6 February | | Super League | Panathinaikos | 0 - 1 | Xanthi FC |
| 2015 3 October | | Super League | Xanthi FC | 0 - 1 | Panathinaikos |
| 2015 25 April | | Super League | Panathinaikos | 2 - 0 | Xanthi FC |
| 2015 29 January | | Cup | Panathinaikos | 0 - 1 | Xanthi FC |
| 2015 21 January | | Cup | Xanthi FC | 1 - 1 | Panathinaikos |
| 2014 18 December | | Super League | Xanthi FC | 4 - 2 | Panathinaikos |
| 2014 13 April | | Super League | Xanthi FC | 3 - 1 | Panathinaikos |
| 2013 22 December | | Super League | Panathinaikos | 2 - 1 | Xanthi FC |
| 2013 9 May | | Super League | Panathinaikos | 3 - 0 | Xanthi FC |
| 2013 10 February | | Super League | Panathinaikos | 0 - 1 | Xanthi FC |
| 2012 7 October | | Super League | Xanthi FC | 1 - 2 | Panathinaikos |
| 2012 12 February | | Super League | Panathinaikos | 3 - 0 | Xanthi FC |
| 2011 16 October | | Super League | Xanthi FC | 2 - 3 | Panathinaikos |
| 2011 4 January | | Super League | Xanthi FC | 0 - 2 | Panathinaikos |
| 2010 27 August | | Super League | Panathinaikos | 1 - 1 | Xanthi FC |
| 2010 9 January | | Super League | Xanthi FC | 1 - 2 | Panathinaikos |
| 2009 30 August | | Super League | Panathinaikos | 1 - 0 | Xanthi FC |
| 2009 5 April | | Super League | Panathinaikos | 2 - 0 | Xanthi FC |
| 2008 6 December | | Super League | Xanthi FC | 1 - 2 | Panathinaikos |
| 2008 16 March | | Super League | Xanthi FC | 3 - 2 | Panathinaikos |
| 2007 1 December | | Super League | Panathinaikos | 0 - 0 | Xanthi FC |
| 2007 17 April | | Cup | Xanthi FC | 0 - 1 | Panathinaikos |
| 2007 27 February | | Cup | Panathinaikos | 0 - 0 | Xanthi FC |
| 2007 20 January | | Super League | Xanthi FC | 0 - 0 | Panathinaikos |
| 2006 8 September | | Super League | Panathinaikos | 1 - 0 | Xanthi FC |
| 2006 1 April | | Super League | Xanthi FC | 1 - 1 | Panathinaikos |
| 2005 25 November | | Super League | Panathinaikos | 2 - 1 | Xanthi FC |
| 2005 29 January | | Super League | Xanthi FC | 3 - 1 | Panathinaikos |
| 2004 24 September | | Super League | Panathinaikos | 3 - 1 | Xanthi FC |
| 2004 10 January | | Super League | Xanthi FC | 0 - 1 | Panathinaikos |
| 2003 23 August | | Super League | Panathinaikos | 1 - 0 | Xanthi FC |
| 2003 12 April | | Super League | Panathinaikos | 1 - 0 | Xanthi FC |
| 2002 14 December | | Super League | Xanthi FC | 0 - 0 | Panathinaikos |
| 2002 19 April | | Super League | Panathinaikos | 3 - 1 | Xanthi FC |
| 2002 19 January | | Super League | Xanthi FC | 1 - 2 | Panathinaikos |
| 2001 16 March | | Super League | Xanthi FC | 0 - 2 | Panathinaikos |
| 2000 24 November | | Super League | Panathinaikos | 3 - 0 | Xanthi FC |
| 2000 21 April | | Super League | Panathinaikos | 2 - 1 | Xanthi FC |
| 1999 21 December | | Super League | Xanthi FC | 1 - 3 | Panathinaikos |
| 1999 1 May | | Super League | Panathinaikos | 2 - 1 | Xanthi FC |
| 1998 29 November | | Super League | Xanthi FC | 1 - 0 | Panathinaikos |
| 1998 14 March | | Super League | Xanthi FC | 1 - 3 | Panathinaikos |
Biggest Xanthi Victory vs Panathinaikos
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| 2005 29 January | | Super League | Xanthi FC | 3 - 1 | Panathinaikos |
Biggest Panathinaikos Victory vs Xanthi
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| 1997 8 November | | Super League | Panathinaikos | 4 - 1 | Xanthi FC |
Biggest Xanthi Defeat vs Panathinaikos
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| 1997 8 November | | Super League | Panathinaikos | 4 - 1 | Xanthi FC |
Biggest Panathinaikos Defeat vs Xanthi
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| 2005 29 January | | Super League | Xanthi FC | 3 - 1 | Panathinaikos |
Last 5 Xanthi Home Matches
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| 2021 27 October | | Cup | Xanthi FC | 1 - 2 | Ionikos |
| 2021 26 May | | Super League | Xanthi FC | 2 - 1 | Panaitolikos |
| 2020 26 August | | Super League | Xanthi FC | 0 - 1 | Apollon Smirnis |
| 2020 11 July | | Super League | Xanthi FC | 1 - 2 | Asteras Tripolis |
| 2020 24 June | | Super League | Xanthi FC | 1 - 0 | Atromitos |
Last 5 Panathinaikos Home Matches
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| 2024 10 November | | Super League | Panathinaikos | 1 - 0 | Lamia |
| 2024 27 October | | Super League | Panathinaikos | 1 - 1 | Aris |
| 2024 24 October | | Europa Conference League | Panathinaikos | 1 - 4 | Chelsea |
| 2024 6 October | | Super League | Panathinaikos | 0 - 0 | Olympiakos Piraeus |
| 2024 22 September | | Super League | Panathinaikos | 3 - 1 | Panserraikos |
Last 5 Xanthi Away Matches
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| 2021 6 October | | Cup | Proodeftiki | 0 - 2 | Xanthi FC |
| 2021 26 September | | Cup | Karaiskakis | 0 - 2 | Xanthi FC |
| 2021 30 May | | Super League | Panaitolikos | 1 - 0 | Xanthi FC |
| 2020 29 August | | Super League | Apollon Smirnis | 3 - 1 | Xanthi FC |
| 2020 18 July | | Super League | Larissa | 0 - 0 | Xanthi FC |
Last 5 Panathinaikos Away Matches
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| 2024 7 November | | Europa Conference League | Djurgarden | 2 - 1 | Panathinaikos |
| 2024 3 November | | Super League | Vo1los NFC | 0 - 1 | Panathinaikos |
| 2024 20 October | | Super League | OFI | 0 - 1 | Panathinaikos |
| 2024 3 October | | Europa Conference League | Borac Banja Luka | 1 - 1 | Panathinaikos |
| 2024 29 September | | Super League | AEK Athens | 2 - 0 | Panathinaikos |