This page lists the head-to-head record of Southampton vs Wolves including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Wolves | Southampton | Draws |
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| Total Matches | 42 | 15 | 15 | 12 |
| At Molineux | 21 | 8 | 9 | 4 |
| At St Mary's Stadium | 21 | 7 | 6 | 8 |
| FA Cup Matches | 1 | 0 | 1 | 0 |
| Carling Cup Matches | 1 | 1 | 0 | 0 |
| Premier League Matches | 32 | 12 | 12 | 8 |
| Championship Matches | 8 | 2 | 2 | 4 |
| Total Goals Scored | 109 | 52 | 57 | |
Last 50 Wolves vs Southampton Matches
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| 2021 14 February | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2021 11 February | | FA Cup | Wolverhampton Wanderers | 0 - 2 | Southampton |
| 2020 23 November | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 2020 18 January | | Premier League | Southampton | 2 - 3 | Wolverhampton Wanderers |
| 2019 19 October | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 2019 13 April | | Premier League | Southampton | 3 - 1 | Wolverhampton Wanderers |
| 2018 29 September | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
| 2017 23 August | | Carling Cup | Southampton | 0 - 2 | Wolverhampton Wanderers |
| 2009 10 April | | Championship | Wolverhampton Wanderers | 3 - 0 | Southampton |
| 2008 15 November | | Championship | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2008 4 March | | Championship | Wolverhampton Wanderers | 2 - 2 | Southampton |
| 2007 6 November | | Championship | Southampton | 0 - 0 | Wolverhampton Wanderers |
| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
| 2006 31 October | | Championship | Southampton | 2 - 0 | Wolverhampton Wanderers |
| 2005 25 November | | Championship | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 2005 5 August | | Championship | Southampton | 0 - 0 | Wolverhampton Wanderers |
| 2004 2 April | | Premier League | Wolverhampton Wanderers | 1 - 4 | Southampton |
| 2003 12 September | | Premier League | Southampton | 2 - 0 | Wolverhampton Wanderers |
| 1984 3 February | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1983 30 September | | Premier League | Southampton | 1 - 0 | Wolverhampton Wanderers |
| 1981 23 November | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1981 31 August | | Premier League | Southampton | 4 - 1 | Wolverhampton Wanderers |
| 1980 12 December | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 1980 6 October | | Premier League | Southampton | 4 - 2 | Wolverhampton Wanderers |
| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
| 1979 25 December | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1979 16 January | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
| 1978 8 September | | Premier League | Southampton | 3 - 2 | Wolverhampton Wanderers |
| 1973 31 December | | Premier League | Wolverhampton Wanderers | 2 - 1 | Southampton |
| 1973 31 August | | Premier League | Southampton | 2 - 1 | Wolverhampton Wanderers |
| 1973 5 January | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1972 25 August | | Premier League | Southampton | 1 - 1 | Wolverhampton Wanderers |
| 1972 10 March | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 1971 8 October | | Premier League | Wolverhampton Wanderers | 4 - 2 | Southampton |
| 1971 16 April | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1970 9 October | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 1969 19 August | | Premier League | Southampton | 2 - 3 | Wolverhampton Wanderers |
| 1969 12 August | | Premier League | Wolverhampton Wanderers | 2 - 1 | Southampton |
| 1969 14 March | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1968 23 August | | Premier League | Southampton | 2 - 1 | Wolverhampton Wanderers |
| 1968 26 April | | Premier League | Southampton | 1 - 1 | Wolverhampton Wanderers |
| 1967 1 December | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
Biggest Wolves Victory vs Southampton
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| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
Biggest Southampton Victory vs Wolves
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| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
Biggest Wolves Defeat vs Southampton
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| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
Biggest Southampton Defeat vs Wolves
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| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
Last 5 Wolves Home Matches
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| 2021 19 February | | Premier League | Wolverhampton Wanderers | 1 - 0 | Leeds United |
| 2021 11 February | | FA Cup | Wolverhampton Wanderers | 0 - 2 | Southampton |
| 2021 7 February | | Premier League | Wolverhampton Wanderers | 0 - 0 | Leicester City |
| 2021 2 February | | Premier League | Wolverhampton Wanderers | 2 - 1 | Arsenal |
| 2021 16 January | | Premier League | Wolverhampton Wanderers | 2 - 3 | West Bromwich Albion |
Last 5 Southampton Home Matches
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| 2021 20 February | | Premier League | Southampton | 1 - 1 | Chelsea |
| 2021 14 February | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2021 30 January | | Premier League | Southampton | 0 - 1 | Aston Villa |
| 2021 26 January | | Premier League | Southampton | 1 - 3 | Arsenal |
| 2021 23 January | | FA Cup | Southampton | 1 - 0 | Arsenal |
Last 5 Wolves Away Matches
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| 2021 14 February | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2021 30 January | | Premier League | Crystal Palace | 1 - 0 | Wolverhampton Wanderers |
| 2021 27 January | | Premier League | Chelsea | 0 - 0 | Wolverhampton Wanderers |
| 2021 22 January | | FA Cup | Chorley | 0 - 1 | Wolverhampton Wanderers |
| 2021 2 January | | Premier League | Brighton & Hove Albion | 3 - 3 | Wolverhampton Wanderers |
Last 5 Southampton Away Matches
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| 2021 23 February | | Premier League | Leeds United | 3 - 0 | Southampton |
| 2021 11 February | | FA Cup | Wolverhampton Wanderers | 0 - 2 | Southampton |
| 2021 6 February | | Premier League | Newcastle United | 3 - 2 | Southampton |
| 2021 2 February | | Premier League | Manchester United | 9 - 0 | Southampton |
| 2021 16 January | | Premier League | Leicester City | 2 - 0 | Southampton |