This page lists the head-to-head record of Santa Clara vs Vitoria Guimaraes including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Vitoria Guimaraes | Santa Clara | Draws |
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| Total Matches | 20 | 11 | 7 | 2 |
| At D. Afonso Henriques | 10 | 3 | 6 | 1 |
| At Estadio de Sao Miguel | 10 | 8 | 1 | 1 |
| Division2 Matches | 2 | 2 | 0 | 0 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Portuguese Liga Matches | 17 | 9 | 6 | 2 |
| Total Goals Scored | 44 | 28 | 16 | |
Last 50 Vitoria Guimaraes vs Santa Clara Matches
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| 2024 10 November | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2023 5 March | | Portuguese Liga | Santa Clara | 1 - 3 | Guimaraes |
| 2022 9 September | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2022 1 May | | Portuguese Liga | Guimaraes | 1 - 1 | Santa Clara |
| 2021 17 December | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2021 17 April | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2020 21 December | | Portuguese Liga | Santa Clara | 0 - 4 | Guimaraes |
| 2020 13 December | | Cup | Guimaraes | 0 - 1 | Santa Clara |
| 2020 24 July | | Portuguese Liga | Santa Clara | 2 - 2 | Guimaraes |
| 2020 18 January | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2019 30 March | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2018 11 November | | Portuguese Liga | Guimaraes | 2 - 0 | Santa Clara |
| 2007 17 March | | Division2 | Santa Clara | 0 - 1 | Guimaraes |
| 2006 21 October | | Division2 | Guimaraes | 1 - 0 | Santa Clara |
| 2003 22 February | | Portuguese Liga | Santa Clara | 2 - 1 | Guimaraes |
| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
| 2002 7 February | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
| 2000 13 May | | Portuguese Liga | Santa Clara | 3 - 2 | Guimaraes |
| 2000 15 January | | Portuguese Liga | Guimaraes | 2 - 1 | Santa Clara |
Biggest Vitoria Guimaraes Victory vs Santa Clara
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| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
Biggest Santa Clara Victory vs Vitoria Guimaraes
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| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
Biggest Vitoria Guimaraes Defeat vs Santa Clara
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| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
Biggest Santa Clara Defeat vs Vitoria Guimaraes
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| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
Last 5 Vitoria Guimaraes Home Matches
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| 2025 3 January | | Portuguese Liga | Guimaraes | 4 - 4 | Sporting Lisbon |
| 2024 23 December | | Portuguese Liga | Guimaraes | 2 - 2 | Nacional |
| 2024 19 December | | Europa Conference League | Guimaraes | 1 - 1 | Fiorentina |
| 2024 2 December | | Portuguese Liga | Guimaraes | 4 - 0 | Gil Vicente |
| 2024 23 November | | Cup | Guimaraes | 2 - 0 | Uniao de Leiria |
Last 5 Santa Clara Home Matches
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| 2025 5 January | | Portuguese Liga | Santa Clara | 0 - 0 | Farense |
| 2024 22 December | | Portuguese Liga | Santa Clara | 0 - 2 | Sporting Braga |
| 2024 7 December | | Portuguese Liga | Santa Clara | 1 - 0 | Rio Ave |
| 2024 10 November | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2024 25 October | | Portuguese Liga | Santa Clara | 2 - 1 | Gil Vicente |
Last 5 Vitoria Guimaraes Away Matches
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| 2025 12 January | | Cup | O Elvas | 2 - 1 | Guimaraes |
| 2024 29 December | | Portuguese Liga | Farense | 2 - 2 | Guimaraes |
| 2024 16 December | | Portuguese Liga | Rio Ave | 2 - 2 | Guimaraes |
| 2024 12 December | | Europa Conference League | St. Gallen | 1 - 4 | Guimaraes |
| 2024 7 December | | Portuguese Liga | Benfica | 1 - 0 | Guimaraes |
Last 5 Santa Clara Away Matches
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| 2024 30 December | | Portuguese Liga | Famalicao | 1 - 2 | Santa Clara |
| 2024 18 December | | Cup | Sporting Lisbon | 1 - 1 | Santa Clara |
| 2024 15 December | | Portuguese Liga | Arouca | 1 - 0 | Santa Clara |
| 2024 30 November | | Portuguese Liga | Sporting Lisbon | 0 - 1 | Santa Clara |
| 2024 24 November | | Cup | Famalicao | 0 - 1 | Santa Clara |