This page lists the head-to-head record of Santa Clara vs Vitoria Guimaraes including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Vitoria Guimaraes | Santa Clara | Draws |
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| Total Matches | 19 | 11 | 6 | 2 |
| At D. Afonso Henriques | 9 | 3 | 5 | 1 |
| At Estadio de Sao Miguel | 10 | 8 | 1 | 1 |
| Division2 Matches | 2 | 2 | 0 | 0 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Portuguese Liga Matches | 16 | 9 | 5 | 2 |
| Total Goals Scored | 43 | 28 | 15 | |
Last 50 Vitoria Guimaraes vs Santa Clara Matches
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| 2023 5 March | | Portuguese Liga | Santa Clara | 1 - 3 | Guimaraes |
| 2022 9 September | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2022 1 May | | Portuguese Liga | Guimaraes | 1 - 1 | Santa Clara |
| 2021 17 December | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2021 17 April | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2020 21 December | | Portuguese Liga | Santa Clara | 0 - 4 | Guimaraes |
| 2020 13 December | | Cup | Guimaraes | 0 - 1 | Santa Clara |
| 2020 24 July | | Portuguese Liga | Santa Clara | 2 - 2 | Guimaraes |
| 2020 18 January | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2019 30 March | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2018 11 November | | Portuguese Liga | Guimaraes | 2 - 0 | Santa Clara |
| 2007 17 March | | Division2 | Santa Clara | 0 - 1 | Guimaraes |
| 2006 21 October | | Division2 | Guimaraes | 1 - 0 | Santa Clara |
| 2003 22 February | | Portuguese Liga | Santa Clara | 2 - 1 | Guimaraes |
| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
| 2002 7 February | | Portuguese Liga | Guimaraes | 1 - 0 | Santa Clara |
| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
| 2000 13 May | | Portuguese Liga | Santa Clara | 3 - 2 | Guimaraes |
| 2000 15 January | | Portuguese Liga | Guimaraes | 2 - 1 | Santa Clara |
Biggest Vitoria Guimaraes Victory vs Santa Clara
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| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
Biggest Santa Clara Victory vs Vitoria Guimaraes
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| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
Biggest Vitoria Guimaraes Defeat vs Santa Clara
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| 2001 15 September | | Portuguese Liga | Santa Clara | 2 - 0 | Guimaraes |
Biggest Santa Clara Defeat vs Vitoria Guimaraes
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| 2002 5 October | | Portuguese Liga | Guimaraes | 5 - 0 | Santa Clara |
Last 5 Vitoria Guimaraes Home Matches
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| 2024 13 April | | Portuguese Liga | Guimaraes | 1 - 1 | Farense |
| 2024 3 April | | Cup | Guimaraes | 0 - 1 | Porto |
| 2024 30 March | | Portuguese Liga | Guimaraes | 1 - 0 | Moreirense |
| 2024 9 March | | Portuguese Liga | Guimaraes | 1 - 0 | Famalicao |
| 2024 24 February | | Portuguese Liga | Guimaraes | 0 - 2 | Casa Pia |
Last 5 Santa Clara Home Matches
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| 2024 20 April | | Segunda Liga | Santa Clara | 1 - 0 | Tondela |
| 2024 7 April | | Segunda Liga | Santa Clara | 0 - 1 | Pacos de Ferreira |
| 2024 17 March | | Segunda Liga | Santa Clara | 0 - 1 | Nacional |
| 2024 29 February | | Cup | Santa Clara | 1 - 2 | Porto |
| 2024 24 February | | Segunda Liga | Santa Clara | 3 - 0 | UD Oliveirense |
Last 5 Vitoria Guimaraes Away Matches
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| 2024 21 April | | Portuguese Liga | Sporting Lisbon | 3 - 0 | Guimaraes |
| 2024 17 April | | Cup | Porto | 3 - 1 | Guimaraes |
| 2024 7 April | | Portuguese Liga | Porto | 1 - 2 | Guimaraes |
| 2024 17 March | | Portuguese Liga | Chaves | 1 - 2 | Guimaraes |
| 2024 2 March | | Portuguese Liga | Estoril | 1 - 3 | Guimaraes |
Last 5 Santa Clara Away Matches
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| 2024 14 April | | Segunda Liga | Maritimo | 0 - 0 | Santa Clara |
| 2024 30 March | | Segunda Liga | AVS | 1 - 2 | Santa Clara |
| 2024 9 March | | Segunda Liga | Benfica II | 0 - 1 | Santa Clara |
| 2024 4 March | | Segunda Liga | Academico Viseu | 1 - 1 | Santa Clara |
| 2024 18 February | | Segunda Liga | Penafiel | 1 - 2 | Santa Clara |