This page lists the head-to-head record of FC Twente vs Vitesse including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Vitesse | FC Twente | Draws |
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| Total Matches | 63 | 21 | 26 | 16 |
| At Gelredome | 32 | 8 | 16 | 8 |
| At De Grolsch Veste | 31 | 13 | 10 | 8 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Eredivisie Matches | 62 | 21 | 25 | 16 |
| Total Goals Scored | 172 | 86 | 86 | |
Last 50 Vitesse vs FC Twente Matches
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| 2024 2 March | | Eredivisie | Vitesse | 1 - 2 | Twente |
| 2023 27 September | | Eredivisie | Twente | 1 - 0 | Vitesse |
| 2023 25 January | | Eredivisie | Vitesse | 2 - 2 | Twente |
| 2022 1 October | | Eredivisie | Twente | 3 - 0 | Vitesse |
| 2022 5 February | | Eredivisie | Twente | 3 - 0 | Vitesse |
| 2021 19 September | | Eredivisie | Vitesse | 1 - 4 | Twente |
| 2021 3 April | | Eredivisie | Twente | 1 - 2 | Vitesse |
| 2021 14 February | | Eredivisie | Vitesse | 0 - 2 | Twente |
| 2020 7 March | | Eredivisie | Vitesse | 1 - 0 | Twente |
| 2019 14 December | | Eredivisie | Twente | 0 - 3 | Vitesse |
| 2018 29 April | | Eredivisie | Vitesse | 5 - 0 | Twente |
| 2017 16 December | | Eredivisie | Twente | 1 - 1 | Vitesse |
| 2017 15 January | | Eredivisie | Vitesse | 3 - 1 | Twente |
| 2016 25 September | | Eredivisie | Twente | 2 - 1 | Vitesse |
| 2016 8 May | | Eredivisie | Twente | 2 - 2 | Vitesse |
| 2015 18 December | | Eredivisie | Vitesse | 5 - 1 | Twente |
| 2015 22 February | | Eredivisie | Twente | 1 - 2 | Vitesse |
| 2014 7 December | | Eredivisie | Vitesse | 2 - 2 | Twente |
| 2014 15 February | | Eredivisie | Twente | 2 - 0 | Vitesse |
| 2013 25 August | | Eredivisie | Vitesse | 1 - 0 | Twente |
| 2013 10 March | | Eredivisie | Twente | 0 - 1 | Vitesse |
| 2012 11 November | | Eredivisie | Vitesse | 0 - 0 | Twente |
| 2012 19 February | | Eredivisie | Vitesse | 1 - 4 | Twente |
| 2011 27 November | | Eredivisie | Twente | 0 - 0 | Vitesse |
| 2011 12 February | | Eredivisie | Twente | 1 - 0 | Vitesse |
| 2010 21 December | | Cup | Twente | 5 - 0 | Vitesse |
| 2010 21 August | | Eredivisie | Vitesse | 0 - 3 | Twente |
| 2010 13 February | | Eredivisie | Vitesse | 1 - 2 | Twente |
| 2009 21 November | | Eredivisie | Twente | 1 - 0 | Vitesse |
| 2009 17 January | | Eredivisie | Twente | 2 - 1 | Vitesse |
| 2008 26 October | | Eredivisie | Vitesse | 0 - 2 | Twente |
| 2008 15 March | | Eredivisie | Twente | 4 - 3 | Vitesse |
| 2007 8 December | | Eredivisie | Vitesse | 2 - 2 | Twente |
| 2007 22 April | | Eredivisie | Vitesse | 1 - 1 | Twente |
| 2006 24 November | | Eredivisie | Twente | 2 - 0 | Vitesse |
| 2006 13 May | | Eredivisie | Twente | 2 - 0 | Vitesse |
| 2006 10 May | | Eredivisie | Vitesse | 1 - 1 | Twente |
| 2006 7 February | | Eredivisie | Vitesse | 1 - 2 | Twente |
| 2005 10 September | | Eredivisie | Twente | 0 - 1 | Vitesse |
| 2005 31 March | | Eredivisie | Vitesse | 1 - 1 | Twente |
| 2004 29 October | | Eredivisie | Twente | 1 - 4 | Vitesse |
| 2004 27 January | | Eredivisie | Twente | 0 - 0 | Vitesse |
| 2003 2 October | | Eredivisie | Vitesse | 3 - 5 | Twente |
| 2003 16 May | | Eredivisie | Vitesse | 0 - 1 | Twente |
| 2002 22 November | | Eredivisie | Twente | 1 - 0 | Vitesse |
| 2002 8 March | | Eredivisie | Vitesse | 2 - 0 | Twente |
| 2001 26 October | | Eredivisie | Twente | 0 - 0 | Vitesse |
| 2001 23 February | | Eredivisie | Twente | 2 - 1 | Vitesse |
| 2000 19 August | | Eredivisie | Vitesse | 3 - 1 | Twente |
| 2000 14 April | | Eredivisie | Vitesse | 4 - 1 | Twente |
Biggest Vitesse Victory vs FC Twente
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| 2018 29 April | | Eredivisie | Vitesse | 5 - 0 | Twente |
Biggest FC Twente Victory vs Vitesse
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| 2010 21 December | | Cup | Twente | 5 - 0 | Vitesse |
Biggest Vitesse Defeat vs FC Twente
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| 2010 21 December | | Cup | Twente | 5 - 0 | Vitesse |
Biggest FC Twente Defeat vs Vitesse
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| 2018 29 April | | Eredivisie | Vitesse | 5 - 0 | Twente |
Last 5 Vitesse Home Matches
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| 2024 29 November | | Eerste Divisie | Vitesse | 2 - 1 | Helmond Sport |
| 2024 22 November | | Eerste Divisie | Vitesse | 0 - 6 | Cambuur |
| 2024 2 November | | Eerste Divisie | Vitesse | 0 - 0 | TOP Oss |
| 2024 25 October | | Eerste Divisie | Vitesse | 1 - 3 | PSV II |
| 2024 4 October | | Eerste Divisie | Vitesse | 1 - 2 | Volendam |
Last 5 FC Twente Home Matches
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| 2024 1 December | | Eredivisie | Twente | 3 - 2 | Go Ahead Eagles |
| 2024 28 November | | UEFA Europa League | Twente | 0 - 1 | Union Saint-Gilloise |
| 2024 10 November | | Eredivisie | Twente | 2 - 2 | Ajax |
| 2024 27 October | | Eredivisie | Twente | 5 - 0 | Heracles |
| 2024 24 October | | UEFA Europa League | Twente | 0 - 2 | Lazio |
Last 5 Vitesse Away Matches
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| 2024 26 November | | Eerste Divisie | Roda JC | 3 - 0 | Vitesse |
| 2024 8 November | | Eerste Divisie | ADO Den Haag | 2 - 0 | Vitesse |
| 2024 30 October | | Cup | RKC Waalwijk | 3 - 1 | Vitesse |
| 2024 22 October | | Eerste Divisie | Dordrecht | 2 - 2 | Vitesse |
| 2024 18 October | | Eerste Divisie | Den Bosch | 4 - 2 | Vitesse |
Last 5 FC Twente Away Matches
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| 2024 23 November | | Eredivisie | Fortuna Sittard | 1 - 2 | Twente |
| 2024 7 November | | UEFA Europa League | Nice | 2 - 2 | Twente |
| 2024 2 November | | Eredivisie | Willem II | 0 - 1 | Twente |
| 2024 19 October | | Eredivisie | RKC Waalwijk | 2 - 2 | Twente |
| 2024 6 October | | Eredivisie | Feyenoord | 2 - 1 | Twente |