This page lists the head-to-head record of FSV Mainz vs VfB Stuttgart including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | VfB Stuttgart | FSV Mainz | Draws |
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| Total Matches | 35 | 15 | 11 | 9 |
| At Mercedes-Benz Arena | 18 | 5 | 8 | 5 |
| At Opel Arena | 17 | 10 | 3 | 4 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Bundesliga Matches | 34 | 15 | 10 | 9 |
| Total Goals Scored | 110 | 60 | 50 | |
Last 50 VfB Stuttgart vs FSV Mainz Matches
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| 2025 25 January | | Bundesliga | Mainz 05 | 2 - 0 | Stuttgart |
| 2024 31 August | | Bundesliga | Stuttgart | 3 - 3 | Mainz 05 |
| 2024 11 February | | Bundesliga | Stuttgart | 3 - 1 | Mainz 05 |
| 2023 16 September | | Bundesliga | Mainz 05 | 1 - 3 | Stuttgart |
| 2023 21 May | | Bundesliga | Mainz 05 | 1 - 4 | Stuttgart |
| 2023 21 January | | Bundesliga | Stuttgart | 1 - 1 | Mainz 05 |
| 2022 16 April | | Bundesliga | Mainz 05 | 0 - 0 | Stuttgart |
| 2021 26 November | | Bundesliga | Stuttgart | 2 - 1 | Mainz 05 |
| 2021 29 January | | Bundesliga | Stuttgart | 2 - 0 | Mainz 05 |
| 2020 26 September | | Bundesliga | Mainz 05 | 1 - 4 | Stuttgart |
| 2019 19 January | | Bundesliga | Stuttgart | 2 - 3 | Mainz 05 |
| 2018 26 August | | Bundesliga | Mainz 05 | 1 - 0 | Stuttgart |
| 2018 20 January | | Bundesliga | Mainz 05 | 3 - 2 | Stuttgart |
| 2017 19 December | | Cup | Mainz 05 | 3 - 1 | Stuttgart |
| 2017 26 August | | Bundesliga | Stuttgart | 1 - 0 | Mainz 05 |
| 2016 7 May | | Bundesliga | Stuttgart | 1 - 3 | Mainz 05 |
| 2015 11 December | | Bundesliga | Mainz 05 | 0 - 0 | Stuttgart |
| 2015 9 May | | Bundesliga | Stuttgart | 2 - 0 | Mainz 05 |
| 2014 13 December | | Bundesliga | Mainz 05 | 1 - 1 | Stuttgart |
| 2014 25 January | | Bundesliga | Stuttgart | 1 - 2 | Mainz 05 |
| 2013 11 August | | Bundesliga | Mainz 05 | 3 - 2 | Stuttgart |
| 2013 18 May | | Bundesliga | Stuttgart | 2 - 2 | Mainz 05 |
| 2012 15 December | | Bundesliga | Mainz 05 | 3 - 1 | Stuttgart |
| 2012 7 April | | Bundesliga | Stuttgart | 4 - 1 | Mainz 05 |
| 2011 4 November | | Bundesliga | Mainz 05 | 3 - 1 | Stuttgart |
| 2011 15 January | | Bundesliga | Stuttgart | 1 - 0 | Mainz 05 |
| 2010 22 August | | Bundesliga | Mainz 05 | 2 - 0 | Stuttgart |
| 2010 1 May | | Bundesliga | Stuttgart | 2 - 2 | Mainz 05 |
| 2009 13 December | | Bundesliga | Mainz 05 | 1 - 1 | Stuttgart |
| 2007 5 May | | Bundesliga | Stuttgart | 2 - 0 | Mainz 05 |
| 2006 1 December | | Bundesliga | Mainz 05 | 0 - 0 | Stuttgart |
| 2006 18 February | | Bundesliga | Stuttgart | 2 - 1 | Mainz 05 |
| 2005 16 September | | Bundesliga | Mainz 05 | 1 - 2 | Stuttgart |
| 2005 21 January | | Bundesliga | Mainz 05 | 2 - 3 | Stuttgart |
| 2004 7 August | | Bundesliga | Stuttgart | 4 - 2 | Mainz 05 |
Biggest VfB Stuttgart Victory vs FSV Mainz
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| 2020 26 September | | Bundesliga | Mainz 05 | 1 - 4 | Stuttgart |
Biggest FSV Mainz Victory vs VfB Stuttgart
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| 2025 25 January | | Bundesliga | Mainz 05 | 2 - 0 | Stuttgart |
Biggest VfB Stuttgart Defeat vs FSV Mainz
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| 2025 25 January | | Bundesliga | Mainz 05 | 2 - 0 | Stuttgart |
Biggest FSV Mainz Defeat vs VfB Stuttgart
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| 2020 26 September | | Bundesliga | Mainz 05 | 1 - 4 | Stuttgart |
Last 5 VfB Stuttgart Home Matches
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| 2025 5 October | | Bundesliga | Stuttgart | 1 - 0 | Heidenheim |
| 2025 25 September | | UEFA Europa League | Stuttgart | 2 - 1 | Celta Vigo |
| 2025 19 September | | Bundesliga | Stuttgart | 2 - 0 | St. Pauli |
| 2025 19 September | | Bundesliga | Stuttgart | 2 - 0 | St. Pauli |
| 2025 30 August | | Bundesliga | Stuttgart | 1 - 0 | Borussia M'gladbach |
Last 5 FSV Mainz Home Matches
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| 2025 27 September | | Bundesliga | Mainz 05 | 0 - 2 | Borussia Dortmund |
| 2025 13 September | | Bundesliga | Mainz 05 | 0 - 1 | RB Leipzig |
| 2025 28 August | | Europa Conference League | Mainz 05 | 4 - 1 | Rosenborg |
| 2025 24 August | | Bundesliga | Mainz 05 | 0 - 1 | FC Koln |
| 2025 24 August | | Bundesliga | Mainz 05 | 0 - 1 | FC Koln |
Last 5 VfB Stuttgart Away Matches
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| 2025 2 October | | UEFA Europa League | Basel | 2 - 0 | Stuttgart |
| 2025 28 September | | Bundesliga | FC Koln | 1 - 2 | Stuttgart |
| 2025 13 September | | Bundesliga | Freiburg | 3 - 1 | Stuttgart |
| 2025 26 August | | Cup | Eintracht Braunschweig | 3 - 3 | Stuttgart |
| 2025 23 August | | Bundesliga | Union Berlin | 2 - 1 | Stuttgart |
Last 5 FSV Mainz Away Matches
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| 2025 5 October | | Bundesliga | Hamburger SV | 4 - 0 | Mainz 05 |
| 2025 2 October | | Europa Conference League | Omonia Nicosia | 0 - 1 | Mainz 05 |
| 2025 20 September | | Bundesliga | Augsburg | 1 - 4 | Mainz 05 |
| 2025 31 August | | Bundesliga | Wolfsburg | 1 - 1 | Mainz 05 |
| 2025 21 August | | Europa Conference League | Rosenborg | 2 - 1 | Mainz 05 |