This page lists the head-to-head record of Wolves vs Southampton including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Southampton | Wolves | Draws |
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| Total Matches | 48 | 15 | 21 | 12 |
| At St Mary's Stadium | 24 | 6 | 10 | 8 |
| At Molineux | 24 | 9 | 11 | 4 |
| FA Cup Matches | 1 | 1 | 0 | 0 |
| Carling Cup Matches | 1 | 0 | 1 | 0 |
| Premier League Matches | 38 | 12 | 18 | 8 |
| Championship Matches | 8 | 2 | 2 | 4 |
| Total Goals Scored | 123 | 60 | 63 | |
Last 50 Southampton vs Wolves Matches
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| 2025 15 March | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2024 9 November | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
| 2023 11 February | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2022 3 September | | Premier League | Wolverhampton Wanderers | 1 - 0 | Southampton |
| 2022 15 January | | Premier League | Wolverhampton Wanderers | 3 - 1 | Southampton |
| 2021 26 September | | Premier League | Southampton | 0 - 1 | Wolverhampton Wanderers |
| 2021 14 February | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2021 11 February | | FA Cup | Wolverhampton Wanderers | 0 - 2 | Southampton |
| 2020 23 November | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 2020 18 January | | Premier League | Southampton | 2 - 3 | Wolverhampton Wanderers |
| 2019 19 October | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 2019 13 April | | Premier League | Southampton | 3 - 1 | Wolverhampton Wanderers |
| 2018 29 September | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
| 2017 23 August | | Carling Cup | Southampton | 0 - 2 | Wolverhampton Wanderers |
| 2009 10 April | | Championship | Wolverhampton Wanderers | 3 - 0 | Southampton |
| 2008 15 November | | Championship | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2008 4 March | | Championship | Wolverhampton Wanderers | 2 - 2 | Southampton |
| 2007 6 November | | Championship | Southampton | 0 - 0 | Wolverhampton Wanderers |
| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
| 2006 31 October | | Championship | Southampton | 2 - 0 | Wolverhampton Wanderers |
| 2005 25 November | | Championship | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 2005 5 August | | Championship | Southampton | 0 - 0 | Wolverhampton Wanderers |
| 2004 2 April | | Premier League | Wolverhampton Wanderers | 1 - 4 | Southampton |
| 2003 12 September | | Premier League | Southampton | 2 - 0 | Wolverhampton Wanderers |
| 1984 3 February | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1983 30 September | | Premier League | Southampton | 1 - 0 | Wolverhampton Wanderers |
| 1981 23 November | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1981 31 August | | Premier League | Southampton | 4 - 1 | Wolverhampton Wanderers |
| 1980 12 December | | Premier League | Wolverhampton Wanderers | 1 - 1 | Southampton |
| 1980 6 October | | Premier League | Southampton | 4 - 2 | Wolverhampton Wanderers |
| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
| 1979 25 December | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1979 16 January | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
| 1978 8 September | | Premier League | Southampton | 3 - 2 | Wolverhampton Wanderers |
| 1973 31 December | | Premier League | Wolverhampton Wanderers | 2 - 1 | Southampton |
| 1973 31 August | | Premier League | Southampton | 2 - 1 | Wolverhampton Wanderers |
| 1973 5 January | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1972 25 August | | Premier League | Southampton | 1 - 1 | Wolverhampton Wanderers |
| 1972 10 March | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 1971 8 October | | Premier League | Wolverhampton Wanderers | 4 - 2 | Southampton |
| 1971 16 April | | Premier League | Wolverhampton Wanderers | 0 - 1 | Southampton |
| 1970 9 October | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 1969 19 August | | Premier League | Southampton | 2 - 3 | Wolverhampton Wanderers |
| 1969 12 August | | Premier League | Wolverhampton Wanderers | 2 - 1 | Southampton |
| 1969 14 March | | Premier League | Wolverhampton Wanderers | 0 - 0 | Southampton |
| 1968 23 August | | Premier League | Southampton | 2 - 1 | Wolverhampton Wanderers |
| 1968 26 April | | Premier League | Southampton | 1 - 1 | Wolverhampton Wanderers |
| 1967 1 December | | Premier League | Wolverhampton Wanderers | 2 - 0 | Southampton |
Biggest Southampton Victory vs Wolves
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| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
Biggest Wolves Victory vs Southampton
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| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
Biggest Southampton Defeat vs Wolves
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| 1980 6 April | | Premier League | Southampton | 0 - 3 | Wolverhampton Wanderers |
Biggest Wolves Defeat vs Southampton
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| 2007 30 March | | Championship | Wolverhampton Wanderers | 0 - 6 | Southampton |
Last 5 Southampton Home Matches
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| 2025 1 November | | Championship | Southampton | 0 - 2 | Preston North End |
| 2025 18 October | | Championship | Southampton | 0 - 0 | Swansea City |
| 2025 27 September | | Championship | Southampton | 1 - 1 | Middlesbrough |
| 2025 14 September | | Championship | Southampton | 0 - 0 | Portsmouth |
| 2025 23 August | | Championship | Southampton | 1 - 2 | Stoke City |
Last 5 Wolves Home Matches
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| 2025 29 October | | Carling Cup | Wolverhampton Wanderers | 3 - 4 | Chelsea |
| 2025 26 October | | Premier League | Wolverhampton Wanderers | 2 - 3 | Burnley |
| 2025 5 October | | Premier League | Wolverhampton Wanderers | 1 - 1 | Brighton & Hove Albion |
| 2025 23 September | | Carling Cup | Wolverhampton Wanderers | 2 - 0 | Everton |
| 2025 20 September | | Premier League | Wolverhampton Wanderers | 1 - 3 | Leeds United |
Last 5 Southampton Away Matches
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| 2025 5 November | | Championship | Queens Park Rangers | 1 - 2 | Southampton |
| 2025 25 October | | Championship | Blackburn Rovers | 2 - 1 | Southampton |
| 2025 21 October | | Championship | Bristol City | 3 - 1 | Southampton |
| 2025 4 October | | Championship | Derby County | 1 - 1 | Southampton |
| 2025 30 September | | Championship | Sheffield United | 1 - 2 | Southampton |
Last 5 Wolves Away Matches
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| 2025 1 November | | Premier League | Fulham | 3 - 0 | Wolverhampton Wanderers |
| 2025 18 October | | Premier League | Sunderland | 2 - 0 | Wolverhampton Wanderers |
| 2025 27 September | | Premier League | Tottenham Hotspur | 1 - 1 | Wolverhampton Wanderers |
| 2025 13 September | | Premier League | Newcastle United | 1 - 0 | Wolverhampton Wanderers |
| 2025 23 August | | Premier League | AFC Bournemouth | 1 - 0 | Wolverhampton Wanderers |