This page lists the head-to-head record of Arsenal vs Southampton including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Southampton | Arsenal | Draws |
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| Total Matches | 96 | 23 | 46 | 27 |
| At St Mary's Stadium | 48 | 4 | 28 | 16 |
| At Emirates Stadium | 48 | 19 | 18 | 11 |
| FA Cup Matches | 2 | 1 | 1 | 0 |
| Carling Cup Matches | 2 | 2 | 0 | 0 |
| Premier League Matches | 92 | 20 | 45 | 27 |
| Total Goals Scored | 265 | 104 | 161 | |
Last 50 Southampton vs Arsenal Matches
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| 2023 21 April | | Premier League | Arsenal | 3 - 3 | Southampton |
| 2022 23 October | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2022 16 April | | Premier League | Southampton | 1 - 0 | Arsenal |
| 2021 11 December | | Premier League | Arsenal | 3 - 0 | Southampton |
| 2021 26 January | | Premier League | Southampton | 1 - 3 | Arsenal |
| 2021 23 January | | FA Cup | Southampton | 1 - 0 | Arsenal |
| 2020 16 December | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2020 25 June | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2019 23 November | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2019 24 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2018 16 December | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2018 8 April | | Premier League | Arsenal | 3 - 2 | Southampton |
| 2017 10 December | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2017 10 May | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2017 28 January | | FA Cup | Southampton | 0 - 5 | Arsenal |
| 2016 30 November | | Carling Cup | Arsenal | 0 - 2 | Southampton |
| 2016 10 September | | Premier League | Arsenal | 2 - 1 | Southampton |
| 2016 2 February | | Premier League | Arsenal | 0 - 0 | Southampton |
| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
| 2015 1 January | | Premier League | Southampton | 2 - 0 | Arsenal |
| 2014 3 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2014 23 September | | Carling Cup | Arsenal | 1 - 2 | Southampton |
| 2014 28 January | | Premier League | Southampton | 2 - 2 | Arsenal |
| 2013 23 November | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2013 1 January | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2005 25 February | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2004 29 October | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2004 9 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2003 28 December | | Premier League | Southampton | 0 - 1 | Arsenal |
| 2003 6 May | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2002 22 November | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2002 1 February | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2001 12 October | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2001 18 May | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2000 1 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2000 25 February | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1999 17 September | | Premier League | Southampton | 0 - 1 | Arsenal |
| 1999 2 April | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1998 16 October | | Premier League | Arsenal | 1 - 1 | Southampton |
| 1998 30 January | | Premier League | Arsenal | 3 - 0 | Southampton |
| 1997 22 August | | Premier League | Southampton | 1 - 3 | Arsenal |
| 1997 14 March | | Premier League | Southampton | 0 - 2 | Arsenal |
| 1996 3 December | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1995 8 December | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1995 22 September | | Premier League | Arsenal | 4 - 2 | Southampton |
| 1995 23 January | | Premier League | Arsenal | 1 - 1 | Southampton |
| 1994 18 November | | Premier League | Southampton | 1 - 0 | Arsenal |
| 1994 18 March | | Premier League | Southampton | 0 - 4 | Arsenal |
| 1993 24 September | | Premier League | Arsenal | 1 - 0 | Southampton |
Biggest Southampton Victory vs Arsenal
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Biggest Arsenal Victory vs Southampton
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Biggest Southampton Defeat vs Arsenal
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Biggest Arsenal Defeat vs Southampton
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Last 5 Southampton Home Matches
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| 2024 16 April | | Championship | Southampton | 3 - 0 | Preston North End |
| 2024 13 April | | Championship | Southampton | 3 - 2 | Watford |
| 2024 9 April | | Championship | Southampton | 2 - 1 | Coventry City |
| 2024 29 March | | Championship | Southampton | 1 - 1 | Middlesbrough |
| 2024 9 March | | Championship | Southampton | 4 - 2 | Sunderland |
Last 5 Arsenal Home Matches
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| 2024 14 April | | Premier League | Arsenal | 0 - 2 | Aston Villa |
| 2024 9 April | | UEFA Champions League | Arsenal | 2 - 2 | Bayern Munchen |
| 2024 3 April | | Premier League | Arsenal | 2 - 0 | Luton Town |
| 2024 12 March | | UEFA Champions League | Arsenal | 1 - 0 | Porto |
| 2024 9 March | | Premier League | Arsenal | 2 - 1 | Brentford |
Last 5 Southampton Away Matches
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| 2024 6 April | | Championship | Blackburn Rovers | 0 - 0 | Southampton |
| 2024 1 April | | Championship | Ipswich Town | 3 - 2 | Southampton |
| 2024 2 March | | Championship | Birmingham City | 3 - 4 | Southampton |
| 2024 28 February | | FA Cup | Liverpool | 3 - 0 | Southampton |
| 2024 16 February | | Championship | West Bromwich Albion | 0 - 2 | Southampton |
Last 5 Arsenal Away Matches
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| 2024 17 April | | UEFA Champions League | Bayern Munchen | 1 - 0 | Arsenal |
| 2024 6 April | | Premier League | Brighton & Hove Albion | 0 - 3 | Arsenal |
| 2024 31 March | | Premier League | Manchester City | 0 - 0 | Arsenal |
| 2024 4 March | | Premier League | Sheffield United | 0 - 6 | Arsenal |
| 2024 21 February | | UEFA Champions League | Porto | 1 - 0 | Arsenal |