This page lists the head-to-head record of Arsenal vs Southampton including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Southampton | Arsenal | Draws |
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| Total Matches | 97 | 23 | 47 | 27 |
| At St Mary's Stadium | 49 | 4 | 29 | 16 |
| At Emirates Stadium | 48 | 19 | 18 | 11 |
| FA Cup Matches | 2 | 1 | 1 | 0 |
| Carling Cup Matches | 2 | 2 | 0 | 0 |
| Premier League Matches | 93 | 20 | 46 | 27 |
| Total Goals Scored | 269 | 105 | 164 | |
Last 50 Southampton vs Arsenal Matches
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| 2024 5 October | | Premier League | Arsenal | 3 - 1 | Southampton |
| 2023 21 April | | Premier League | Arsenal | 3 - 3 | Southampton |
| 2022 23 October | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2022 16 April | | Premier League | Southampton | 1 - 0 | Arsenal |
| 2021 11 December | | Premier League | Arsenal | 3 - 0 | Southampton |
| 2021 26 January | | Premier League | Southampton | 1 - 3 | Arsenal |
| 2021 23 January | | FA Cup | Southampton | 1 - 0 | Arsenal |
| 2020 16 December | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2020 25 June | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2019 23 November | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2019 24 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2018 16 December | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2018 8 April | | Premier League | Arsenal | 3 - 2 | Southampton |
| 2017 10 December | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2017 10 May | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2017 28 January | | FA Cup | Southampton | 0 - 5 | Arsenal |
| 2016 30 November | | Carling Cup | Arsenal | 0 - 2 | Southampton |
| 2016 10 September | | Premier League | Arsenal | 2 - 1 | Southampton |
| 2016 2 February | | Premier League | Arsenal | 0 - 0 | Southampton |
| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
| 2015 1 January | | Premier League | Southampton | 2 - 0 | Arsenal |
| 2014 3 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2014 23 September | | Carling Cup | Arsenal | 1 - 2 | Southampton |
| 2014 28 January | | Premier League | Southampton | 2 - 2 | Arsenal |
| 2013 23 November | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2013 1 January | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2005 25 February | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2004 29 October | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2004 9 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2003 28 December | | Premier League | Southampton | 0 - 1 | Arsenal |
| 2003 6 May | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2002 22 November | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2002 1 February | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2001 12 October | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2001 18 May | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2000 1 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2000 25 February | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1999 17 September | | Premier League | Southampton | 0 - 1 | Arsenal |
| 1999 2 April | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1998 16 October | | Premier League | Arsenal | 1 - 1 | Southampton |
| 1998 30 January | | Premier League | Arsenal | 3 - 0 | Southampton |
| 1997 22 August | | Premier League | Southampton | 1 - 3 | Arsenal |
| 1997 14 March | | Premier League | Southampton | 0 - 2 | Arsenal |
| 1996 3 December | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1995 8 December | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1995 22 September | | Premier League | Arsenal | 4 - 2 | Southampton |
| 1995 23 January | | Premier League | Arsenal | 1 - 1 | Southampton |
| 1994 18 November | | Premier League | Southampton | 1 - 0 | Arsenal |
| 1994 18 March | | Premier League | Southampton | 0 - 4 | Arsenal |
Biggest Southampton Victory vs Arsenal
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Biggest Arsenal Victory vs Southampton
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Biggest Southampton Defeat vs Arsenal
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Biggest Arsenal Defeat vs Southampton
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Last 5 Southampton Home Matches
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| 2025 26 April | | Premier League | Southampton | 1 - 2 | Fulham |
| 2025 12 April | | Premier League | Southampton | 0 - 3 | Aston Villa |
| 2025 2 April | | Premier League | Southampton | 1 - 1 | Crystal Palace |
| 2025 15 March | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2025 22 February | | Premier League | Southampton | 0 - 4 | Brighton & Hove Albion |
Last 5 Arsenal Home Matches
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| 2025 3 May | | Premier League | Arsenal | 1 - 2 | AFC Bournemouth |
| 2025 29 April | | UEFA Champions League | Arsenal | 0 - 1 | Paris St Germain |
| 2025 23 April | | Premier League | Arsenal | 2 - 2 | Crystal Palace |
| 2025 12 April | | Premier League | Arsenal | 1 - 1 | Brentford |
| 2025 8 April | | UEFA Champions League | Arsenal | 3 - 0 | Real Madrid |
Last 5 Southampton Away Matches
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| 2025 3 May | | Premier League | Leicester City | 2 - 0 | Southampton |
| 2025 19 April | | Premier League | West Ham United | 1 - 1 | Southampton |
| 2025 6 April | | Premier League | Tottenham Hotspur | 3 - 1 | Southampton |
| 2025 8 March | | Premier League | Liverpool | 3 - 1 | Southampton |
| 2025 25 February | | Premier League | Chelsea | 4 - 0 | Southampton |
Last 5 Arsenal Away Matches
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| 2025 20 April | | Premier League | Ipswich Town | 0 - 4 | Arsenal |
| 2025 16 April | | UEFA Champions League | Real Madrid | 1 - 2 | Arsenal |
| 2025 5 April | | Premier League | Everton | 1 - 1 | Arsenal |
| 2025 9 March | | Premier League | Manchester United | 1 - 1 | Arsenal |
| 2025 4 March | | UEFA Champions League | PSV | 1 - 7 | Arsenal |