This page lists the head-to-head record of CD Nacional vs Santa Clara including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Santa Clara | CD Nacional | Draws |
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| Total Matches | 14 | 5 | 5 | 4 |
| At Estadio de Sao Miguel | 7 | 2 | 3 | 2 |
| At Est·dio da Madeira | 7 | 3 | 2 | 2 |
| Division2 Matches | 2 | 1 | 1 | 0 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Portuguese Liga Matches | 7 | 4 | 3 | 0 |
| Segunda Liga Matches | 4 | 0 | 1 | 3 |
| Total Goals Scored | 42 | 24 | 18 | |
Last 50 Santa Clara vs CD Nacional Matches
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
| 2024 17 March | | Segunda Liga | Santa Clara | 0 - 1 | Nacional |
| 2024 11 January | | Cup | Santa Clara | 0 - 0 | Nacional |
| 2023 4 November | | Segunda Liga | Nacional | 1 - 1 | Santa Clara |
| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
| 2020 6 December | | Portuguese Liga | Nacional | 1 - 3 | Santa Clara |
| 2019 24 February | | Portuguese Liga | Santa Clara | 2 - 0 | Nacional |
| 2018 30 September | | Portuguese Liga | Nacional | 0 - 3 | Santa Clara |
| 2018 15 April | | Segunda Liga | Nacional | 3 - 3 | Santa Clara |
| 2017 3 December | | Segunda Liga | Santa Clara | 1 - 1 | Nacional |
| 2003 18 April | | Portuguese Liga | Nacional | 2 - 1 | Santa Clara |
| 2002 16 November | | Portuguese Liga | Santa Clara | 2 - 3 | Nacional |
| 2001 31 March | | Division2 | Nacional | 2 - 1 | Santa Clara |
| 2000 28 October | | Division2 | Santa Clara | 2 - 1 | Nacional |
Biggest Santa Clara Victory vs CD Nacional
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| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
Biggest CD Nacional Victory vs Santa Clara
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
Biggest Santa Clara Defeat vs CD Nacional
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
Biggest CD Nacional Defeat vs Santa Clara
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| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
Last 5 Santa Clara Home Matches
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| 2024 10 November | | Portuguese Liga | Santa Clara | 1 - 0 | Guimaraes |
| 2024 25 October | | Portuguese Liga | Santa Clara | 2 - 1 | Gil Vicente |
| 2024 29 September | | Portuguese Liga | Santa Clara | 1 - 0 | Boavista |
| 2024 21 September | | Portuguese Liga | Santa Clara | 1 - 0 | Estrela P |
| 2024 31 August | | Portuguese Liga | Santa Clara | 2 - 1 | AVS |
Last 5 CD Nacional Home Matches
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
| 2024 20 September | | Portuguese Liga | Nacional | 0 - 3 | Sporting Braga |
| 2024 1 September | | Portuguese Liga | Nacional | 2 - 0 | Farense |
| 2024 17 August | | Portuguese Liga | Nacional | 1 - 6 | Sporting Lisbon |
| 2024 19 May | | Segunda Liga | Nacional | 2 - 0 | Mafra |
Last 5 Santa Clara Away Matches
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
| 2024 19 October | | Cup | Gondomar | 0 - 1 | Santa Clara |
| 2024 5 October | | Portuguese Liga | Moreirense | 1 - 0 | Santa Clara |
| 2024 14 September | | Portuguese Liga | Benfica | 4 - 1 | Santa Clara |
| 2024 24 August | | Portuguese Liga | Casa Pia | 0 - 2 | Santa Clara |
Last 5 CD Nacional Away Matches
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| 2024 10 November | | Portuguese Liga | Estrela P | 2 - 0 | Nacional |
| 2024 25 October | | Portuguese Liga | Casa Pia | 1 - 0 | Nacional |
| 2024 20 October | | Cup | Uniao de Leiria | 2 - 1 | Nacional |
| 2024 29 September | | Portuguese Liga | Famalicao | 0 - 0 | Nacional |
| 2024 15 September | | Portuguese Liga | Estoril | 1 - 0 | Nacional |