This page lists the head-to-head record of Lecce vs Sampdoria including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Sampdoria | Lecce | Draws |
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| Total Matches | 21 | 12 | 4 | 5 |
| At Luigi Ferraris | 10 | 7 | 1 | 2 |
| At Stadio Via del Mare | 11 | 5 | 3 | 3 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Serie B Matches | 2 | 1 | 1 | 0 |
| Serie A Matches | 18 | 10 | 3 | 5 |
| Total Goals Scored | 72 | 46 | 26 | |
Last 50 Sampdoria vs Lecce Matches
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| 2023 16 April | | Serie A | Lecce | 1 - 1 | Sampdoria |
| 2022 12 November | | Serie A | Sampdoria | 0 - 2 | Lecce |
| 2020 1 July | | Serie A | Lecce | 1 - 2 | Sampdoria |
| 2019 30 October | | Serie A | Sampdoria | 1 - 1 | Lecce |
| 2011 10 April | | Serie A | Sampdoria | 1 - 2 | Lecce |
| 2010 21 November | | Serie A | Lecce | 2 - 3 | Sampdoria |
| 2009 16 August | | Cup | Sampdoria | 6 - 2 | Lecce |
| 2009 11 April | | Serie A | Lecce | 1 - 3 | Sampdoria |
| 2008 16 November | | Serie A | Sampdoria | 3 - 2 | Lecce |
| 2006 13 May | | Serie A | Sampdoria | 1 - 3 | Lecce |
| 2006 13 January | | Serie A | Lecce | 0 - 3 | Sampdoria |
| 2005 7 May | | Serie A | Sampdoria | 3 - 0 | Lecce |
| 2004 18 December | | Serie A | Lecce | 1 - 4 | Sampdoria |
| 2004 27 March | | Serie A | Sampdoria | 2 - 2 | Lecce |
| 2003 22 November | | Serie A | Lecce | 0 - 0 | Sampdoria |
| 2003 9 February | | Serie B | Lecce | 1 - 0 | Sampdoria |
| 2002 13 September | | Serie B | Sampdoria | 4 - 2 | Lecce |
| 1998 9 May | | Serie A | Sampdoria | 1 - 1 | Lecce |
| 1998 17 January | | Serie A | Lecce | 1 - 3 | Sampdoria |
| 1994 29 January | | Serie A | Lecce | 0 - 3 | Sampdoria |
| 1993 11 September | | Serie A | Sampdoria | 2 - 1 | Lecce |
Biggest Sampdoria Victory vs Lecce
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| 2009 16 August | | Cup | Sampdoria | 6 - 2 | Lecce |
Biggest Lecce Victory vs Sampdoria
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| 2006 13 May | | Serie A | Sampdoria | 1 - 3 | Lecce |
Biggest Sampdoria Defeat vs Lecce
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| 2006 13 May | | Serie A | Sampdoria | 1 - 3 | Lecce |
Biggest Lecce Defeat vs Sampdoria
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| 2009 16 August | | Cup | Sampdoria | 6 - 2 | Lecce |
Last 5 Sampdoria Home Matches
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| 2025 2 November | | Serie B | Sampdoria | 0 - 1 | Mantova |
| 2025 25 October | | Serie B | Sampdoria | 1 - 1 | Frosinone |
| 2025 5 October | | Serie B | Sampdoria | 4 - 1 | Pescara |
| 2025 1 October | | Serie B | Sampdoria | 0 - 0 | Catanzaro |
| 2025 13 September | | Serie B | Sampdoria | 1 - 2 | Cesena |
Last 5 Lecce Home Matches
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| 2025 8 November | | Serie A | Lecce | 0 - 0 | Hellas Verona |
| 2025 28 October | | Serie A | Lecce | 0 - 1 | Napoli |
| 2025 18 October | | Serie A | Lecce | 0 - 0 | Sassuolo |
| 2025 28 September | | Serie A | Lecce | 2 - 2 | Bologna |
| 2025 19 September | | Serie A | Lecce | 1 - 2 | Cagliari |
Last 5 Sampdoria Away Matches
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| 2025 8 November | | Serie B | Venezia | 3 - 1 | Sampdoria |
| 2025 28 October | | Serie B | Empoli | 1 - 1 | Sampdoria |
| 2025 17 October | | Serie B | Virtus Entella | 3 - 1 | Sampdoria |
| 2025 27 September | | Serie B | Bari 1908 | 1 - 1 | Sampdoria |
| 2025 20 September | | Serie B | Monza | 1 - 0 | Sampdoria |
Last 5 Lecce Away Matches
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| 2025 23 November | | Serie A | Lazio | 2 - 0 | Lecce |
| 2025 2 November | | Serie A | Fiorentina | 0 - 1 | Lecce |
| 2025 25 October | | Serie A | Udinese | 3 - 2 | Lecce |
| 2025 4 October | | Serie A | Parma | 0 - 1 | Lecce |
| 2025 23 September | | Cup | Milan | 3 - 0 | Lecce |