This page lists the head-to-head record of Grosseto vs Sampdoria including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Sampdoria | Grosseto | Draws |
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| Total Matches | 2 | 1 | 0 | 1 |
| At Luigi Ferraris | 1 | 1 | 0 | 0 |
| At Stadio Carlo Zecchini | 1 | 0 | 0 | 1 |
| Serie B Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 1 | 1 | 0 | |
Last 50 Sampdoria vs Grosseto Matches
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
| 2011 17 September | | Serie B | Sampdoria | 0 - 0 | Grosseto |
Biggest Sampdoria Victory vs Grosseto
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
Biggest Grosseto Defeat vs Sampdoria
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
Last 5 Sampdoria Home Matches
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| 2024 3 November | | Serie B | Sampdoria | 0 - 1 | Brescia |
| 2024 27 October | | Serie B | Sampdoria | 1 - 0 | Mantova |
| 2024 4 October | | Serie B | Sampdoria | 1 - 2 | Juve Stabia |
| 2024 21 September | | Serie B | Sampdoria | 1 - 0 | Sudtirol |
| 2024 31 August | | Serie B | Sampdoria | 0 - 0 | Bari 1908 |
Last 5 Grosseto Home Matches
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| 2022 14 April | | Serie C1 - A | Grosseto | 0 - 2 | Lucchese |
| 2022 3 April | | Serie C1 - A | Grosseto | 0 - 0 | Robur Siena |
| 2022 19 March | | Serie C1 - A | Grosseto | 1 - 0 | Virtus Entella |
| 2022 15 March | | Serie C1 - A | Grosseto | 0 - 0 | Pontedera |
| 2022 6 March | | Serie C1 - A | Grosseto | 2 - 0 | Imolese |
Last 5 Sampdoria Away Matches
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| 2024 9 November | | Serie B | Pisa | 3 - 0 | Sampdoria |
| 2024 30 October | | Serie B | Cittadella | 0 - 0 | Sampdoria |
| 2024 20 October | | Serie B | Cesena | 3 - 5 | Sampdoria |
| 2024 29 September | | Serie B | Modena | 1 - 3 | Sampdoria |
| 2024 25 September | | Cup | Genoa | 1 - 1 | Sampdoria |
Last 5 Grosseto Away Matches
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| 2022 23 April | | Serie C1 - A | Olbia | 3 - 1 | Grosseto |
| 2022 9 April | | Serie C1 - A | Pescara | 2 - 1 | Grosseto |
| 2022 27 March | | Serie C1 - A | Montevarchi Calcio | 1 - 1 | Grosseto |
| 2022 12 March | | Serie C1 - A | Vis Pesaro | 2 - 1 | Grosseto |
| 2022 27 February | | Serie C1 - A | Teramo | 2 - 1 | Grosseto |