This page lists the head-to-head record of AC Milan vs Sampdoria including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Sampdoria | AC Milan | Draws |
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| Total Matches | 53 | 12 | 30 | 11 |
| At Luigi Ferraris | 25 | 4 | 16 | 5 |
| At San Siro | 28 | 8 | 14 | 6 |
| Cup Matches | 3 | 0 | 2 | 1 |
| Serie A Matches | 50 | 12 | 28 | 10 |
| Total Goals Scored | 131 | 44 | 87 | |
Last 50 Sampdoria vs AC Milan Matches
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| 2023 20 May | | Serie A | Milan | 5 - 1 | Sampdoria |
| 2022 10 September | | Serie A | Sampdoria | 1 - 2 | Milan |
| 2022 13 February | | Serie A | Milan | 1 - 0 | Sampdoria |
| 2021 23 August | | Serie A | Sampdoria | 0 - 1 | Milan |
| 2021 3 April | | Serie A | Milan | 1 - 1 | Sampdoria |
| 2020 6 December | | Serie A | Sampdoria | 1 - 2 | Milan |
| 2020 29 July | | Serie A | Sampdoria | 1 - 4 | Milan |
| 2020 6 January | | Serie A | Milan | 0 - 0 | Sampdoria |
| 2019 30 March | | Serie A | Sampdoria | 1 - 0 | Milan |
| 2019 12 January | | Cup | Sampdoria | 0 - 0 | Milan |
| 2018 28 October | | Serie A | Milan | 3 - 2 | Sampdoria |
| 2018 18 February | | Serie A | Milan | 1 - 0 | Sampdoria |
| 2017 24 September | | Serie A | Sampdoria | 2 - 0 | Milan |
| 2017 5 February | | Serie A | Milan | 0 - 1 | Sampdoria |
| 2016 16 September | | Serie A | Sampdoria | 0 - 1 | Milan |
| 2016 17 April | | Serie A | Sampdoria | 0 - 1 | Milan |
| 2015 17 December | | Cup | Sampdoria | 0 - 2 | Milan |
| 2015 28 November | | Serie A | Milan | 4 - 1 | Sampdoria |
| 2015 12 April | | Serie A | Milan | 1 - 1 | Sampdoria |
| 2014 8 November | | Serie A | Sampdoria | 2 - 2 | Milan |
| 2014 23 February | | Serie A | Sampdoria | 0 - 2 | Milan |
| 2013 28 September | | Serie A | Milan | 1 - 0 | Sampdoria |
| 2013 13 January | | Serie A | Sampdoria | 0 - 0 | Milan |
| 2012 26 August | | Serie A | Milan | 0 - 1 | Sampdoria |
| 2011 16 April | | Serie A | Milan | 3 - 0 | Sampdoria |
| 2011 26 January | | Cup | Sampdoria | 1 - 2 | Milan |
| 2010 27 November | | Serie A | Sampdoria | 1 - 1 | Milan |
| 2010 18 April | | Serie A | Sampdoria | 2 - 1 | Milan |
| 2009 5 December | | Serie A | Milan | 3 - 0 | Sampdoria |
| 2009 1 March | | Serie A | Sampdoria | 2 - 1 | Milan |
| 2008 19 October | | Serie A | Milan | 3 - 0 | Sampdoria |
| 2008 19 March | | Serie A | Milan | 1 - 2 | Sampdoria |
| 2007 31 October | | Serie A | Sampdoria | 0 - 5 | Milan |
| 2007 25 February | | Serie A | Milan | 1 - 0 | Sampdoria |
| 2006 14 October | | Serie A | Sampdoria | 1 - 1 | Milan |
| 2006 27 January | | Serie A | Milan | 1 - 1 | Sampdoria |
| 2005 17 September | | Serie A | Sampdoria | 2 - 1 | Milan |
| 2005 12 March | | Serie A | Milan | 1 - 0 | Sampdoria |
| 2004 29 October | | Serie A | Sampdoria | 0 - 1 | Milan |
| 2004 6 March | | Serie A | Milan | 3 - 1 | Sampdoria |
| 2003 25 October | | Serie A | Sampdoria | 0 - 3 | Milan |
| 1999 1 May | | Serie A | Milan | 3 - 2 | Sampdoria |
| 1998 19 December | | Serie A | Sampdoria | 2 - 2 | Milan |
| 1998 7 March | | Serie A | Milan | 1 - 0 | Sampdoria |
| 1997 1 November | | Serie A | Sampdoria | 0 - 3 | Milan |
| 1997 1 February | | Serie A | Milan | 2 - 3 | Sampdoria |
| 1996 14 September | | Serie A | Sampdoria | 2 - 1 | Milan |
| 1996 4 May | | Serie A | Sampdoria | 3 - 0 | Milan |
| 1996 6 January | | Serie A | Milan | 3 - 0 | Sampdoria |
| 1995 18 March | | Serie A | Sampdoria | 0 - 3 | Milan |
Biggest Sampdoria Victory vs AC Milan
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| 1996 4 May | | Serie A | Sampdoria | 3 - 0 | Milan |
Biggest AC Milan Victory vs Sampdoria
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| 2007 31 October | | Serie A | Sampdoria | 0 - 5 | Milan |
Biggest Sampdoria Defeat vs AC Milan
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| 2007 31 October | | Serie A | Sampdoria | 0 - 5 | Milan |
Biggest AC Milan Defeat vs Sampdoria
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| 1996 4 May | | Serie A | Sampdoria | 3 - 0 | Milan |
Last 5 Sampdoria Home Matches
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| 2025 25 October | | Serie B | Sampdoria | 1 - 1 | Frosinone |
| 2025 5 October | | Serie B | Sampdoria | 4 - 1 | Pescara |
| 2025 1 October | | Serie B | Sampdoria | 0 - 0 | Catanzaro |
| 2025 13 September | | Serie B | Sampdoria | 1 - 2 | Cesena |
| 2025 25 August | | Serie B | Sampdoria | 0 - 2 | Modena |
Last 5 AC Milan Home Matches
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| 2025 24 October | | Serie A | Milan | 2 - 2 | Pisa |
| 2025 19 October | | Serie A | Milan | 2 - 1 | Fiorentina |
| 2025 28 September | | Serie A | Milan | 2 - 1 | Napoli |
| 2025 23 September | | Cup | Milan | 3 - 0 | Lecce |
| 2025 14 September | | Serie A | Milan | 1 - 0 | Bologna |
Last 5 Sampdoria Away Matches
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| 2025 17 October | | Serie B | Virtus Entella | 3 - 1 | Sampdoria |
| 2025 27 September | | Serie B | Bari 1908 | 1 - 1 | Sampdoria |
| 2025 20 September | | Serie B | Monza | 1 - 0 | Sampdoria |
| 2025 31 August | | Serie B | Sudtirol | 3 - 1 | Sampdoria |
| 2025 18 August | | Cup | Spezia | 1 - 1 | Sampdoria |
Last 5 AC Milan Away Matches
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| 2025 5 October | | Serie A | Juventus | 0 - 0 | Milan |
| 2025 20 September | | Serie A | Udinese | 0 - 3 | Milan |
| 2025 29 August | | Serie A | Lecce | 0 - 2 | Milan |
| 2025 18 May | | Serie A | Roma | 3 - 1 | Milan |
| 2025 5 May | | Serie A | Genoa | 1 - 2 | Milan |