This page lists the head-to-head record of Southampton vs Reading including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Reading | Southampton | Draws |
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| Total Matches | 8 | 2 | 3 | 3 |
| At Madejski | 4 | 1 | 1 | 2 |
| At St Mary's Stadium | 4 | 1 | 2 | 1 |
| Premier League Matches | 2 | 0 | 2 | 0 |
| Championship Matches | 6 | 2 | 1 | 3 |
| Total Goals Scored | 16 | 8 | 8 | |
Last 50 Reading vs Southampton Matches
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
| 2012 8 December | | Premier League | Southampton | 1 - 0 | Reading |
| 2012 13 April | | Championship | Southampton | 1 - 3 | Reading |
| 2011 22 October | | Championship | Reading | 1 - 1 | Southampton |
| 2008 28 December | | Championship | Southampton | 1 - 1 | Reading |
| 2008 22 November | | Championship | Reading | 1 - 2 | Southampton |
| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
| 2005 27 September | | Championship | Southampton | 0 - 0 | Reading |
Biggest Reading Victory vs Southampton
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Biggest Southampton Victory vs Reading
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Reading Defeat vs Southampton
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Southampton Defeat vs Reading
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Last 5 Reading Home Matches
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| 2025 29 March | | League One | Reading | 3 - 1 | Peterborough United |
| 2025 15 March | | League One | Reading | 1 - 1 | Stevenage |
| 2025 11 March | | League One | Reading | 2 - 0 | Wrexham |
| 2025 4 March | | League One | Reading | 0 - 0 | Exeter City |
| 2025 22 February | | League One | Reading | 0 - 0 | Birmingham City |
Last 5 Southampton Home Matches
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| 2025 2 April | | Premier League | Southampton | 1 - 1 | Crystal Palace |
| 2025 15 March | | Premier League | Southampton | 1 - 2 | Wolverhampton Wanderers |
| 2025 22 February | | Premier League | Southampton | 0 - 4 | Brighton & Hove Albion |
| 2025 15 February | | Premier League | Southampton | 1 - 3 | AFC Bournemouth |
| 2025 8 February | | FA Cup | Southampton | 0 - 1 | Burnley |
Last 5 Reading Away Matches
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| 2025 1 April | | League One | Blackpool | 3 - 0 | Reading |
| 2025 8 March | | League One | Crawley Town | 1 - 1 | Reading |
| 2025 1 March | | League One | Wigan Athletic | 1 - 2 | Reading |
| 2025 8 February | | League One | Huddersfield Town | 0 - 0 | Reading |
| 2025 28 January | | League One | Burton Albion | 3 - 2 | Reading |
Last 5 Southampton Away Matches
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| 2025 8 March | | Premier League | Liverpool | 3 - 1 | Southampton |
| 2025 25 February | | Premier League | Chelsea | 4 - 0 | Southampton |
| 2025 1 February | | Premier League | Ipswich Town | 1 - 2 | Southampton |
| 2025 19 January | | Premier League | Nottingham Forest | 3 - 2 | Southampton |
| 2025 16 January | | Premier League | Manchester United | 3 - 1 | Southampton |