This page lists the head-to-head record of Southampton vs Reading including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Reading | Southampton | Draws |
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| Total Matches | 8 | 2 | 3 | 3 |
| At Madejski | 4 | 1 | 1 | 2 |
| At St Mary's Stadium | 4 | 1 | 2 | 1 |
| Premier League Matches | 2 | 0 | 2 | 0 |
| Championship Matches | 6 | 2 | 1 | 3 |
| Total Goals Scored | 16 | 8 | 8 | |
Last 50 Reading vs Southampton Matches
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
| 2012 8 December | | Premier League | Southampton | 1 - 0 | Reading |
| 2012 13 April | | Championship | Southampton | 1 - 3 | Reading |
| 2011 22 October | | Championship | Reading | 1 - 1 | Southampton |
| 2008 28 December | | Championship | Southampton | 1 - 1 | Reading |
| 2008 22 November | | Championship | Reading | 1 - 2 | Southampton |
| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
| 2005 27 September | | Championship | Southampton | 0 - 0 | Reading |
Biggest Reading Victory vs Southampton
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Biggest Southampton Victory vs Reading
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Reading Defeat vs Southampton
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Southampton Defeat vs Reading
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Last 5 Reading Home Matches
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| 2025 22 November | | League One | Reading | 1 - 1 | Rotherham United |
| 2025 6 November | | League One | Reading | 1 - 0 | Stevenage |
| 2025 1 November | | FA Cup | Reading | 2 - 2 | Carlisle United |
| 2025 25 October | | League One | Reading | 1 - 1 | Doncaster Rovers |
| 2025 21 October | | League One | Reading | 1 - 0 | Northampton Town |
Last 5 Southampton Home Matches
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| 2025 6 December | | Championship | Southampton | 3 - 1 | Birmingham City |
| 2025 25 November | | Championship | Southampton | 3 - 0 | Leicester City |
| 2025 8 November | | Championship | Southampton | 3 - 1 | Sheffield Wednesday |
| 2025 1 November | | Championship | Southampton | 0 - 2 | Preston North End |
| 2025 18 October | | Championship | Southampton | 0 - 0 | Swansea City |
Last 5 Reading Away Matches
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| 2025 29 November | | League One | Blackpool | 0 - 3 | Reading |
| 2025 18 October | | League One | Cardiff City | 2 - 1 | Reading |
| 2025 11 October | | League One | Exeter City | 1 - 1 | Reading |
| 2025 27 September | | League One | Stockport County | 1 - 1 | Reading |
| 2025 23 September | | Carling Cup | Wrexham | 2 - 0 | Reading |
Last 5 Southampton Away Matches
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| 2025 29 November | | Championship | Millwall | 3 - 2 | Southampton |
| 2025 22 November | | Championship | Charlton Athletic | 1 - 5 | Southampton |
| 2025 5 November | | Championship | Queens Park Rangers | 1 - 2 | Southampton |
| 2025 25 October | | Championship | Blackburn Rovers | 2 - 1 | Southampton |
| 2025 21 October | | Championship | Bristol City | 3 - 1 | Southampton |