This page lists the head-to-head record of Southampton vs Reading including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Reading | Southampton | Draws |
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| Total Matches | 8 | 2 | 3 | 3 |
| At Madejski | 4 | 1 | 1 | 2 |
| At St Mary's Stadium | 4 | 1 | 2 | 1 |
| Premier League Matches | 2 | 0 | 2 | 0 |
| Championship Matches | 6 | 2 | 1 | 3 |
| Total Goals Scored | 16 | 8 | 8 | |
Last 50 Reading vs Southampton Matches
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
| 2012 8 December | | Premier League | Southampton | 1 - 0 | Reading |
| 2012 13 April | | Championship | Southampton | 1 - 3 | Reading |
| 2011 22 October | | Championship | Reading | 1 - 1 | Southampton |
| 2008 28 December | | Championship | Southampton | 1 - 1 | Reading |
| 2008 22 November | | Championship | Reading | 1 - 2 | Southampton |
| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
| 2005 27 September | | Championship | Southampton | 0 - 0 | Reading |
Biggest Reading Victory vs Southampton
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Biggest Southampton Victory vs Reading
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Reading Defeat vs Southampton
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| 2013 6 April | | Premier League | Reading | 0 - 2 | Southampton |
Biggest Southampton Defeat vs Reading
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| 2006 9 February | | Championship | Reading | 2 - 0 | Southampton |
Last 5 Reading Home Matches
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| 2026 14 March | | League One | Reading | 2 - 2 | Plymouth Argyle |
| 2026 28 February | | League One | Reading | 2 - 1 | Bradford City |
| 2026 17 February | | League One | Reading | 1 - 1 | Bolton Wanderers |
| 2026 14 February | | League One | Reading | 3 - 2 | Wycombe Wanderers |
| 2026 27 January | | League One | Reading | 2 - 2 | Exeter City |
Last 5 Southampton Home Matches
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| 2026 21 March | | Championship | Southampton | 2 - 0 | Oxford United |
| 2026 18 March | | Championship | Southampton | 1 - 0 | Norwich City |
| 2026 24 February | | Championship | Southampton | 5 - 0 | Queens Park Rangers |
| 2026 21 February | | Championship | Southampton | 1 - 1 | Charlton Athletic |
| 2026 14 February | | FA Cup | Southampton | 1 - 1 | Leicester City |
Last 5 Reading Away Matches
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| 2026 21 March | | League One | Stevenage | 1 - 0 | Reading |
| 2026 17 March | | League One | Burton Albion | 1 - 2 | Reading |
| 2026 10 March | | League One | Mansfield Town | 1 - 0 | Reading |
| 2026 7 March | | League One | Luton Town | 2 - 3 | Reading |
| 2026 21 February | | League One | Port Vale | 1 - 1 | Reading |
Last 5 Southampton Away Matches
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| 2026 14 March | | Championship | Coventry City | 1 - 2 | Southampton |
| 2026 11 March | | Championship | West Bromwich Albion | 1 - 1 | Southampton |
| 2026 8 March | | FA Cup | Fulham | 0 - 1 | Southampton |
| 2026 28 February | | Championship | Sheffield Wednesday | 1 - 3 | Southampton |
| 2026 10 February | | Championship | Leicester City | 3 - 4 | Southampton |