This page lists the head-to-head record of Sampdoria vs Perugia including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Perugia | Sampdoria | Draws |
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| Total Matches | 6 | 2 | 2 | 2 |
| At | 3 | 0 | 2 | 1 |
| At Luigi Ferraris | 3 | 2 | 0 | 1 |
| Serie A Matches | 6 | 2 | 2 | 2 |
| Total Goals Scored | 23 | 11 | 12 | |
Last 50 Perugia vs Sampdoria Matches
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| 2004 17 April | | Serie A | Sampdoria | 3 - 2 | Perugia |
| 2003 12 December | | Serie A | Perugia | 3 - 3 | Sampdoria |
| 1999 30 January | | Serie A | Perugia | 2 - 0 | Sampdoria |
| 1998 19 September | | Serie A | Sampdoria | 1 - 1 | Perugia |
| 1997 25 January | | Serie A | Sampdoria | 5 - 2 | Perugia |
| 1996 7 September | | Serie A | Perugia | 1 - 0 | Sampdoria |
Biggest Perugia Victory vs Sampdoria
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| 1999 30 January | | Serie A | Perugia | 2 - 0 | Sampdoria |
Biggest Sampdoria Victory vs Perugia
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| 1997 25 January | | Serie A | Sampdoria | 5 - 2 | Perugia |
Biggest Perugia Defeat vs Sampdoria
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| 1997 25 January | | Serie A | Sampdoria | 5 - 2 | Perugia |
Biggest Sampdoria Defeat vs Perugia
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| 1999 30 January | | Serie A | Perugia | 2 - 0 | Sampdoria |
Last 5 Perugia Home Matches
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| 2026 20 March | | Serie C1 - A | Perugia | 1 - 1 | Torres |
| 2026 9 March | | Serie C1 - A | Perugia | 2 - 1 | Pontedera |
| 2026 28 February | | Serie C1 - A | Perugia | 0 - 1 | Pineto |
| 2026 15 February | | Serie C1 - A | Perugia | 1 - 1 | Athletic Carpi |
| 2026 30 January | | Serie C1 - A | Perugia | 1 - 1 | Ravenna |
Last 5 Sampdoria Home Matches
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| 2026 22 March | | Serie B | Sampdoria | 2 - 1 | Avellino |
| 2026 14 March | | Serie B | Sampdoria | 0 - 0 | Venezia |
| 2026 27 February | | Serie B | Sampdoria | 0 - 2 | Bari 1908 |
| 2026 14 February | | Serie B | Sampdoria | 1 - 0 | Calcio Padova |
| 2026 10 February | | Serie B | Sampdoria | 3 - 3 | Palermo |
Last 5 Perugia Away Matches
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| 2026 29 March | | Serie C1 - A | Vis Pesaro | 0 - 1 | Perugia |
| 2026 15 March | | Serie C1 - A | Arezzo | 1 - 1 | Perugia |
| 2026 4 March | | Serie C1 - A | Livorno | 1 - 2 | Perugia |
| 2026 12 February | | Serie C1 - A | Pianese | 2 - 1 | Perugia |
| 2026 8 February | | Serie C1 - A | Sambenedettese | 0 - 1 | Perugia |
Last 5 Sampdoria Away Matches
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| 2026 18 March | | Serie B | Carrarese | 2 - 0 | Sampdoria |
| 2026 8 March | | Serie B | Frosinone | 3 - 0 | Sampdoria |
| 2026 4 March | | Serie B | Juve Stabia | 1 - 1 | Sampdoria |
| 2026 21 February | | Serie B | Mantova | 2 - 1 | Sampdoria |
| 2026 7 February | | Serie B | Modena | 1 - 2 | Sampdoria |