This page lists the head-to-head record of CD Nacional vs Penafiel including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Penafiel | CD Nacional | Draws |
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| Total Matches | 23 | 8 | 11 | 4 |
| At Estadio Municipal 25 de Abril | 12 | 3 | 6 | 3 |
| At Est·dio da Madeira | 11 | 5 | 5 | 1 |
| Division2 Matches | 6 | 4 | 2 | 0 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Portuguese Liga Matches | 6 | 2 | 4 | 0 |
| Segunda Liga Matches | 10 | 2 | 5 | 3 |
| Total Goals Scored | 65 | 28 | 37 | |
Last 50 Penafiel vs CD Nacional Matches
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| 2024 24 February | | Segunda Liga | Nacional | 3 - 2 | Penafiel |
| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
| 2022 29 October | | Segunda Liga | Nacional | 1 - 1 | Penafiel |
| 2022 13 February | | Segunda Liga | Nacional | 3 - 0 | Penafiel |
| 2021 12 September | | Segunda Liga | Penafiel | 1 - 0 | Nacional |
| 2020 29 February | | Segunda Liga | Penafiel | 1 - 1 | Nacional |
| 2019 21 September | | Segunda Liga | Nacional | 2 - 1 | Penafiel |
| 2018 14 January | | Segunda Liga | Penafiel | 0 - 3 | Nacional |
| 2017 6 August | | Segunda Liga | Nacional | 1 - 1 | Penafiel |
| 2015 26 April | | Portuguese Liga | Nacional | 2 - 0 | Penafiel |
| 2014 13 December | | Portuguese Liga | Penafiel | 2 - 1 | Nacional |
| 2007 20 January | | Cup | Nacional | 0 - 0 | Penafiel |
| 2006 18 February | | Portuguese Liga | Penafiel | 1 - 2 | Nacional |
| 2005 1 October | | Portuguese Liga | Nacional | 2 - 0 | Penafiel |
| 2005 13 May | | Portuguese Liga | Nacional | 1 - 3 | Penafiel |
| 2005 8 January | | Portuguese Liga | Penafiel | 0 - 1 | Nacional |
| 2002 19 January | | Division2 | Nacional | 4 - 1 | Penafiel |
| 2001 18 August | | Division2 | Penafiel | 0 - 2 | Nacional |
| 2001 3 February | | Division2 | Nacional | 0 - 2 | Penafiel |
| 2000 9 September | | Division2 | Penafiel | 3 - 1 | Nacional |
| 1998 2 May | | Division2 | Penafiel | 3 - 2 | Nacional |
| 1998 2 January | | Division2 | Nacional | 1 - 2 | Penafiel |
Biggest Penafiel Victory vs CD Nacional
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| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
Biggest CD Nacional Victory vs Penafiel
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| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
Biggest Penafiel Defeat vs CD Nacional
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| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
Biggest CD Nacional Defeat vs Penafiel
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| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
Last 5 Penafiel Home Matches
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| 2024 9 November | | Segunda Liga | Penafiel | 2 - 1 | Felgueiras 1932 |
| 2024 26 October | | Segunda Liga | Penafiel | 0 - 2 | Academico Viseu |
| 2024 21 October | | Cup | Penafiel | 2 - 2 | Lusitania |
| 2024 6 October | | Segunda Liga | Penafiel | 1 - 0 | Uniao de Leiria |
| 2024 15 September | | Segunda Liga | Penafiel | 1 - 1 | Porto II |
Last 5 CD Nacional Home Matches
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
| 2024 20 September | | Portuguese Liga | Nacional | 0 - 3 | Sporting Braga |
| 2024 1 September | | Portuguese Liga | Nacional | 2 - 0 | Farense |
| 2024 17 August | | Portuguese Liga | Nacional | 1 - 6 | Sporting Lisbon |
| 2024 19 May | | Segunda Liga | Nacional | 2 - 0 | Mafra |
Last 5 Penafiel Away Matches
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| 2024 2 November | | Segunda Liga | Maritimo | 1 - 2 | Penafiel |
| 2024 12 October | | Segunda Liga | Alverca | 2 - 2 | Penafiel |
| 2024 28 September | | Segunda Liga | Portimonense | 0 - 2 | Penafiel |
| 2024 21 September | | Cup | Tocha | 1 - 4 | Penafiel |
| 2024 1 September | | Segunda Liga | Pacos de Ferreira | 1 - 3 | Penafiel |
Last 5 CD Nacional Away Matches
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| 2024 10 November | | Portuguese Liga | Estrela P | 2 - 0 | Nacional |
| 2024 25 October | | Portuguese Liga | Casa Pia | 1 - 0 | Nacional |
| 2024 20 October | | Cup | Uniao de Leiria | 2 - 1 | Nacional |
| 2024 29 September | | Portuguese Liga | Famalicao | 0 - 0 | Nacional |
| 2024 15 September | | Portuguese Liga | Estoril | 1 - 0 | Nacional |