This page lists the head-to-head record of Xanthi vs Panionios including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Panionios | Xanthi | Draws |
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| Total Matches | 53 | 17 | 21 | 15 |
| At Panionios Stadium | 26 | 6 | 14 | 6 |
| At Skoda Xanthi Arena | 27 | 11 | 7 | 9 |
| Super League Matches | 51 | 17 | 20 | 14 |
| Cup Matches | 2 | 0 | 1 | 1 |
| Total Goals Scored | 113 | 48 | 65 | |
Last 50 Panionios vs Xanthi Matches
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| 2020 27 June | | Super League | Panionios | 2 - 1 | Xanthi FC |
| 2020 8 February | | Super League | Panionios | 0 - 0 | Xanthi FC |
| 2019 10 November | | Super League | Xanthi FC | 1 - 2 | Panionios |
| 2019 17 March | | Super League | Panionios | 1 - 0 | Xanthi FC |
| 2018 10 November | | Super League | Xanthi FC | 0 - 1 | Panionios |
| 2018 1 April | | Super League | Panionios | 0 - 0 | Xanthi FC |
| 2017 19 November | | Super League | Xanthi FC | 2 - 0 | Panionios |
| 2017 5 February | | Super League | Panionios | 2 - 0 | Xanthi FC |
| 2016 17 September | | Super League | Xanthi FC | 0 - 2 | Panionios |
| 2016 12 March | | Super League | Panionios | 3 - 0 | Xanthi FC |
| 2015 22 November | | Super League | Xanthi FC | 2 - 0 | Panionios |
| 2015 4 February | | Super League | Xanthi FC | 1 - 1 | Panionios |
| 2014 27 September | | Super League | Panionios | 1 - 1 | Xanthi FC |
| 2014 23 March | | Super League | Xanthi FC | 2 - 0 | Panionios |
| 2013 1 December | | Super League | Panionios | 0 - 0 | Xanthi FC |
| 2013 14 April | | Super League | Panionios | 3 - 3 | Xanthi FC |
| 2012 9 December | | Super League | Xanthi FC | 4 - 0 | Panionios |
| 2012 18 April | | Super League | Panionios | 1 - 1 | Xanthi FC |
| 2011 17 December | | Super League | Xanthi FC | 1 - 0 | Panionios |
| 2011 9 January | | Super League | Panionios | 0 - 2 | Xanthi FC |
| 2010 12 September | | Super League | Xanthi FC | 1 - 1 | Panionios |
| 2010 7 March | | Super League | Panionios | 3 - 0 | Xanthi FC |
| 2009 8 November | | Super League | Xanthi FC | 1 - 2 | Panionios |
| 2009 3 January | | Super League | Xanthi FC | 0 - 0 | Panionios |
| 2008 31 August | | Super League | Panionios | 0 - 1 | Xanthi FC |
| 2008 2 March | | Super League | Xanthi FC | 1 - 2 | Panionios |
| 2007 11 November | | Super League | Panionios | 3 - 2 | Xanthi FC |
| 2007 18 March | | Super League | Xanthi FC | 1 - 1 | Panionios |
| 2007 9 January | | Cup | Xanthi FC | 0 - 0 | Panionios |
| 2006 19 December | | Cup | Panionios | 0 - 1 | Xanthi FC |
| 2006 18 November | | Super League | Panionios | 0 - 2 | Xanthi FC |
| 2006 8 April | | Super League | Xanthi FC | 1 - 0 | Panionios |
| 2005 4 December | | Super League | Panionios | 0 - 2 | Xanthi FC |
| 2005 9 April | | Super League | Xanthi FC | 3 - 0 | Panionios |
| 2004 4 December | | Super League | Panionios | 0 - 0 | Xanthi FC |
| 2004 17 January | | Super League | Panionios | 1 - 0 | Xanthi FC |
| 2003 30 August | | Super League | Xanthi FC | 0 - 0 | Panionios |
| 2003 14 March | | Super League | Xanthi FC | 0 - 1 | Panionios |
| 2002 23 November | | Super League | Panionios | 0 - 3 | Xanthi FC |
| 2002 6 April | | Super League | Panionios | 2 - 0 | Xanthi FC |
| 2001 15 December | | Super League | Xanthi FC | 3 - 1 | Panionios |
| 2001 17 February | | Super League | Xanthi FC | 3 - 1 | Panionios |
| 2000 28 October | | Super League | Panionios | 0 - 0 | Xanthi FC |
| 2000 11 March | | Super League | Panionios | 4 - 0 | Xanthi FC |
| 1999 30 October | | Super League | Xanthi FC | 5 - 0 | Panionios |
| 1999 15 May | | Super League | Panionios | 0 - 2 | Xanthi FC |
| 1998 20 December | | Super League | Xanthi FC | 1 - 0 | Panionios |
| 1998 28 March | | Super League | Panionios | 1 - 1 | Xanthi FC |
| 1997 22 November | | Super League | Xanthi FC | 2 - 0 | Panionios |
| 1996 23 March | | Super League | Xanthi FC | 4 - 0 | Panionios |
Biggest Panionios Victory vs Xanthi
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| 2000 11 March | | Super League | Panionios | 4 - 0 | Xanthi FC |
Biggest Xanthi Victory vs Panionios
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| 1999 30 October | | Super League | Xanthi FC | 5 - 0 | Panionios |
Biggest Panionios Defeat vs Xanthi
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| 1999 30 October | | Super League | Xanthi FC | 5 - 0 | Panionios |
Biggest Xanthi Defeat vs Panionios
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| 2000 11 March | | Super League | Panionios | 4 - 0 | Xanthi FC |
Last 5 Panionios Home Matches
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| 2024 20 April | | C Ethniki | Panionios | 4 - 0 | Atromitos Piraeus |
| 2024 7 April | | C Ethniki | Panionios | 5 - 0 | Ellopiakos |
| 2024 24 March | | C Ethniki | Panionios | 1 - 2 | Apollon Smirnis |
| 2024 10 March | | C Ethniki | Panionios | 1 - 1 | Ipato |
| 2024 3 March | | C Ethniki | Panionios | 5 - 0 | Atsalenios |
Last 5 Xanthi Home Matches
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| 2021 27 October | | Cup | Xanthi FC | 1 - 2 | Ionikos |
| 2021 26 May | | Super League | Xanthi FC | 2 - 1 | Panaitolikos |
| 2020 26 August | | Super League | Xanthi FC | 0 - 1 | Apollon Smirnis |
| 2020 11 July | | Super League | Xanthi FC | 1 - 2 | Asteras Tripolis |
| 2020 24 June | | Super League | Xanthi FC | 1 - 0 | Atromitos |
Last 5 Panionios Away Matches
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| 2024 14 April | | C Ethniki | Ethnikos Piraeus | 2 - 0 | Panionios |
| 2024 31 March | | C Ethniki | Ermis Zoniana | 3 - 4 | Panionios |
| 2024 16 March | | C Ethniki | Chaidari | 2 - 2 | Panionios |
| 2024 25 February | | C Ethniki | Fostiras | 0 - 1 | Panionios |
| 2024 11 February | | C Ethniki | Ilisiakos | 0 - 1 | Panionios |
Last 5 Xanthi Away Matches
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| 2021 6 October | | Cup | Proodeftiki | 0 - 2 | Xanthi FC |
| 2021 26 September | | Cup | Karaiskakis | 0 - 2 | Xanthi FC |
| 2021 30 May | | Super League | Panaitolikos | 1 - 0 | Xanthi FC |
| 2020 29 August | | Super League | Apollon Smirnis | 3 - 1 | Xanthi FC |
| 2020 18 July | | Super League | Larissa | 0 - 0 | Xanthi FC |