This page lists the head-to-head record of Lecce vs Palermo including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Palermo | Lecce | Draws |
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| Total Matches | 14 | 8 | 3 | 3 |
| At Stadio Renzo Barbera | 7 | 2 | 3 | 2 |
| At Stadio Via del Mare | 7 | 6 | 0 | 1 |
| Serie B Matches | 4 | 3 | 1 | 0 |
| Serie A Matches | 10 | 5 | 2 | 3 |
| Total Goals Scored | 46 | 27 | 19 | |
Last 50 Palermo vs Lecce Matches
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| 2019 2 March | | Serie B | Palermo | 2 - 1 | Lecce |
| 2018 21 October | | Serie B | Lecce | 1 - 2 | Palermo |
| 2012 18 March | | Serie A | Lecce | 1 - 1 | Palermo |
| 2011 27 October | | Serie A | Palermo | 2 - 0 | Lecce |
| 2011 6 February | | Serie A | Lecce | 2 - 4 | Palermo |
| 2010 26 September | | Serie A | Palermo | 2 - 2 | Lecce |
| 2009 15 March | | Serie A | Palermo | 5 - 2 | Lecce |
| 2008 29 October | | Serie A | Lecce | 1 - 1 | Palermo |
| 2006 4 March | | Serie A | Lecce | 2 - 0 | Palermo |
| 2005 25 October | | Serie A | Palermo | 3 - 0 | Lecce |
| 2005 19 February | | Serie A | Palermo | 3 - 2 | Lecce |
| 2004 16 October | | Serie A | Lecce | 2 - 0 | Palermo |
| 2003 6 June | | Serie B | Lecce | 3 - 0 | Palermo |
| 2003 18 January | | Serie B | Palermo | 2 - 0 | Lecce |
Biggest Palermo Victory vs Lecce
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| 2009 15 March | | Serie A | Palermo | 5 - 2 | Lecce |
Biggest Lecce Victory vs Palermo
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| 2003 6 June | | Serie B | Lecce | 3 - 0 | Palermo |
Biggest Palermo Defeat vs Lecce
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| 2003 6 June | | Serie B | Lecce | 3 - 0 | Palermo |
Biggest Lecce Defeat vs Palermo
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| 2009 15 March | | Serie A | Palermo | 5 - 2 | Lecce |
Last 5 Palermo Home Matches
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| 2025 1 May | | Serie B | Palermo | 1 - 2 | Sudtirol |
| 2025 6 April | | Serie B | Palermo | 5 - 3 | Sassuolo |
| 2025 14 March | | Serie B | Palermo | 2 - 3 | Cremonese |
| 2025 2 March | | Serie B | Palermo | 1 - 0 | Brescia |
| 2025 16 February | | Serie B | Palermo | 2 - 2 | Mantova |
Last 5 Lecce Home Matches
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| 2025 3 May | | Serie A | Lecce | 0 - 1 | Napoli |
| 2025 19 April | | Serie A | Lecce | 0 - 3 | Como |
| 2025 6 April | | Serie A | Lecce | 1 - 1 | Venezia |
| 2025 29 March | | Serie A | Lecce | 0 - 1 | Roma |
| 2025 8 March | | Serie A | Lecce | 2 - 3 | Milan |
Last 5 Palermo Away Matches
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| 2025 4 May | | Serie B | Cesena | 2 - 1 | Palermo |
| 2025 27 April | | Serie B | Catanzaro | 1 - 3 | Palermo |
| 2025 11 April | | Serie B | Bari 1908 | 2 - 1 | Palermo |
| 2025 30 March | | Serie B | Salernitana | 1 - 2 | Palermo |
| 2025 8 March | | Serie B | Sampdoria | 1 - 1 | Palermo |
Last 5 Lecce Away Matches
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| 2025 27 April | | Serie A | Atalanta | 1 - 1 | Lecce |
| 2025 12 April | | Serie A | Juventus | 2 - 1 | Lecce |
| 2025 14 March | | Serie A | Genoa | 2 - 1 | Lecce |
| 2025 28 February | | Serie A | Fiorentina | 1 - 0 | Lecce |
| 2025 16 February | | Serie A | Monza | 0 - 0 | Lecce |