This page lists the head-to-head record of Siena vs Napoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Napoli | Siena | Draws |
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| Total Matches | 16 | 7 | 5 | 4 |
| At Stadio San Paolo | 8 | 1 | 4 | 3 |
| At Montepaschi Arena | 8 | 6 | 1 | 1 |
| Cup Matches | 2 | 1 | 1 | 0 |
| Serie B Matches | 4 | 1 | 3 | 0 |
| Serie A Matches | 10 | 5 | 1 | 4 |
| Total Goals Scored | 35 | 20 | 15 | |
Last 50 Napoli vs Siena Matches
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| 2013 12 May | | Serie A | Napoli | 2 - 1 | Robur Siena |
| 2012 22 December | | Serie A | Robur Siena | 0 - 2 | Napoli |
| 2012 13 May | | Serie A | Napoli | 2 - 1 | Robur Siena |
| 2012 21 March | | Cup | Napoli | 2 - 0 | Robur Siena |
| 2012 9 February | | Cup | Robur Siena | 2 - 1 | Napoli |
| 2012 22 January | | Serie A | Robur Siena | 1 - 1 | Napoli |
| 2010 21 February | | Serie A | Robur Siena | 0 - 0 | Napoli |
| 2009 27 September | | Serie A | Napoli | 2 - 1 | Robur Siena |
| 2009 3 May | | Serie A | Robur Siena | 2 - 1 | Napoli |
| 2008 7 December | | Serie A | Napoli | 2 - 0 | Robur Siena |
| 2008 27 April | | Serie A | Napoli | 0 - 0 | Robur Siena |
| 2007 16 December | | Serie A | Robur Siena | 1 - 1 | Napoli |
| 2003 4 April | | Serie B | Robur Siena | 2 - 0 | Napoli |
| 2002 1 November | | Serie B | Napoli | 1 - 2 | Robur Siena |
| 2002 25 May | | Serie B | Robur Siena | 2 - 1 | Napoli |
| 2001 22 December | | Serie B | Napoli | 2 - 0 | Robur Siena |
Biggest Napoli Victory vs Siena
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| 2008 7 December | | Serie A | Napoli | 2 - 0 | Robur Siena |
Biggest Siena Victory vs Napoli
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| 2003 4 April | | Serie B | Robur Siena | 2 - 0 | Napoli |
Biggest Napoli Defeat vs Siena
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| 2003 4 April | | Serie B | Robur Siena | 2 - 0 | Napoli |
Biggest Siena Defeat vs Napoli
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| 2008 7 December | | Serie A | Napoli | 2 - 0 | Robur Siena |
Last 5 Napoli Home Matches
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| 2024 3 November | | Serie A | Napoli | 0 - 3 | Atalanta |
| 2024 26 October | | Serie A | Napoli | 1 - 0 | Lecce |
| 2024 4 October | | Serie A | Napoli | 3 - 1 | Como |
| 2024 29 September | | Serie A | Napoli | 2 - 0 | Monza |
| 2024 26 September | | Cup | Napoli | 5 - 0 | Palermo |
Last 5 Siena Home Matches
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| 2023 23 April | | Serie C1 - A | Robur Siena | 1 - 2 | Virtus Entella |
| 2023 6 April | | Serie C1 - A | Robur Siena | 2 - 2 | Gubbio |
| 2023 18 March | | Serie C1 - A | Robur Siena | 0 - 0 | Alessandria |
| 2023 11 March | | Serie C1 - A | Robur Siena | 4 - 0 | Vis Pesaro |
| 2023 25 February | | Serie C1 - A | Robur Siena | 1 - 1 | Recanatese |
Last 5 Napoli Away Matches
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| 2024 10 November | | Serie A | Internazionale | 1 - 1 | Napoli |
| 2024 29 October | | Serie A | Milan | 0 - 2 | Napoli |
| 2024 20 October | | Serie A | Empoli | 0 - 1 | Napoli |
| 2024 21 September | | Serie A | Juventus | 0 - 0 | Napoli |
| 2024 15 September | | Serie A | Cagliari | 0 - 4 | Napoli |
Last 5 Siena Away Matches
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| 2023 15 April | | Serie C1 - A | Fiorenzuola | 1 - 1 | Robur Siena |
| 2023 1 April | | Serie C1 - A | Fermana | 3 - 1 | Robur Siena |
| 2023 26 March | | Serie C1 - A | Carrarese | 3 - 0 | Robur Siena |
| 2023 14 March | | Serie C1 - A | Lucchese | 1 - 1 | Robur Siena |
| 2023 5 March | | Serie C1 - A | San Donato Tavarnelle | 1 - 1 | Robur Siena |