This page lists the head-to-head record of Empoli vs Napoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Napoli | Empoli | Draws |
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| Total Matches | 25 | 11 | 10 | 4 |
| At Stadio San Paolo | 12 | 3 | 7 | 2 |
| At Stadio Carlo Castellani | 13 | 8 | 3 | 2 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Serie B Matches | 4 | 1 | 2 | 1 |
| Serie A Matches | 20 | 9 | 8 | 3 |
| Total Goals Scored | 76 | 40 | 36 | |
Last 50 Napoli vs Empoli Matches
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| 2025 14 April | | Serie A | Napoli | 3 - 0 | Empoli |
| 2024 20 October | | Serie A | Empoli | 0 - 1 | Napoli |
| 2024 20 April | | Serie A | Empoli | 1 - 0 | Napoli |
| 2023 12 November | | Serie A | Napoli | 0 - 1 | Empoli |
| 2023 25 February | | Serie A | Empoli | 0 - 2 | Napoli |
| 2022 8 November | | Serie A | Napoli | 2 - 0 | Empoli |
| 2022 24 April | | Serie A | Empoli | 3 - 2 | Napoli |
| 2021 12 December | | Serie A | Napoli | 0 - 1 | Empoli |
| 2021 13 January | | Cup | Napoli | 3 - 2 | Empoli |
| 2019 3 April | | Serie A | Empoli | 2 - 1 | Napoli |
| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
| 2017 19 March | | Serie A | Empoli | 2 - 3 | Napoli |
| 2016 26 October | | Serie A | Napoli | 2 - 0 | Empoli |
| 2016 31 January | | Serie A | Napoli | 5 - 1 | Empoli |
| 2015 13 September | | Serie A | Empoli | 2 - 2 | Napoli |
| 2015 30 April | | Serie A | Empoli | 4 - 2 | Napoli |
| 2014 7 December | | Serie A | Napoli | 2 - 2 | Empoli |
| 2008 17 February | | Serie A | Napoli | 1 - 3 | Empoli |
| 2007 23 September | | Serie A | Empoli | 0 - 0 | Napoli |
| 2002 17 February | | Serie B | Napoli | 0 - 0 | Empoli |
| 2001 22 September | | Serie B | Empoli | 1 - 0 | Napoli |
| 2000 7 May | | Serie B | Empoli | 4 - 1 | Napoli |
| 1999 4 December | | Serie B | Napoli | 1 - 0 | Empoli |
| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
| 1997 13 September | | Serie A | Napoli | 2 - 1 | Empoli |
Biggest Napoli Victory vs Empoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Biggest Empoli Victory vs Napoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Napoli Defeat vs Empoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Empoli Defeat vs Napoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Last 5 Napoli Home Matches
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| 2025 5 October | | Serie A | Napoli | 2 - 1 | Genoa |
| 2025 1 October | | UEFA Champions League | Napoli | 2 - 1 | Sporting Lisbon |
| 2025 22 September | | Serie A | Napoli | 3 - 2 | Pisa |
| 2025 30 August | | Serie A | Napoli | 1 - 0 | Cagliari |
| 2025 23 May | | Serie A | Napoli | 2 - 0 | Cagliari |
Last 5 Empoli Home Matches
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| 2025 1 October | | Serie B | Empoli | 1 - 1 | Monza |
| 2025 28 September | | Serie B | Empoli | 2 - 2 | Carrarese |
| 2025 14 September | | Serie B | Empoli | 1 - 1 | Spezia |
| 2025 23 August | | Serie B | Empoli | 3 - 1 | Calcio Padova |
| 2025 15 August | | Cup | Empoli | 1 - 1 | Reggiana |
Last 5 Napoli Away Matches
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| 2025 28 September | | Serie A | Milan | 2 - 1 | Napoli |
| 2025 18 September | | UEFA Champions League | Manchester City | 2 - 0 | Napoli |
| 2025 13 September | | Serie A | Fiorentina | 1 - 3 | Napoli |
| 2025 23 August | | Serie A | Sassuolo | 0 - 2 | Napoli |
| 2025 18 May | | Serie A | Parma | 0 - 0 | Napoli |
Last 5 Empoli Away Matches
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| 2025 5 October | | Serie B | Sudtirol | 1 - 2 | Empoli |
| 2025 25 September | | Cup | Genoa | 3 - 1 | Empoli |
| 2025 21 September | | Serie B | Pescara | 4 - 0 | Empoli |
| 2025 29 August | | Serie B | Reggiana | 3 - 1 | Empoli |
| 2025 18 May | | Serie A | Monza | 1 - 3 | Empoli |