This page lists the head-to-head record of Empoli vs Napoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Napoli | Empoli | Draws |
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| Total Matches | 24 | 10 | 10 | 4 |
| At Stadio San Paolo | 12 | 3 | 7 | 2 |
| At Stadio Carlo Castellani | 12 | 7 | 3 | 2 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Serie B Matches | 4 | 1 | 2 | 1 |
| Serie A Matches | 19 | 8 | 8 | 3 |
| Total Goals Scored | 73 | 37 | 36 | |
Last 50 Napoli vs Empoli Matches
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| 2024 20 October | | Serie A | Empoli | 0 - 1 | Napoli |
| 2024 20 April | | Serie A | Empoli | 1 - 0 | Napoli |
| 2023 12 November | | Serie A | Napoli | 0 - 1 | Empoli |
| 2023 25 February | | Serie A | Empoli | 0 - 2 | Napoli |
| 2022 8 November | | Serie A | Napoli | 2 - 0 | Empoli |
| 2022 24 April | | Serie A | Empoli | 3 - 2 | Napoli |
| 2021 12 December | | Serie A | Napoli | 0 - 1 | Empoli |
| 2021 13 January | | Cup | Napoli | 3 - 2 | Empoli |
| 2019 3 April | | Serie A | Empoli | 2 - 1 | Napoli |
| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
| 2017 19 March | | Serie A | Empoli | 2 - 3 | Napoli |
| 2016 26 October | | Serie A | Napoli | 2 - 0 | Empoli |
| 2016 31 January | | Serie A | Napoli | 5 - 1 | Empoli |
| 2015 13 September | | Serie A | Empoli | 2 - 2 | Napoli |
| 2015 30 April | | Serie A | Empoli | 4 - 2 | Napoli |
| 2014 7 December | | Serie A | Napoli | 2 - 2 | Empoli |
| 2008 17 February | | Serie A | Napoli | 1 - 3 | Empoli |
| 2007 23 September | | Serie A | Empoli | 0 - 0 | Napoli |
| 2002 17 February | | Serie B | Napoli | 0 - 0 | Empoli |
| 2001 22 September | | Serie B | Empoli | 1 - 0 | Napoli |
| 2000 7 May | | Serie B | Empoli | 4 - 1 | Napoli |
| 1999 4 December | | Serie B | Napoli | 1 - 0 | Empoli |
| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
| 1997 13 September | | Serie A | Napoli | 2 - 1 | Empoli |
Biggest Napoli Victory vs Empoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Biggest Empoli Victory vs Napoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Napoli Defeat vs Empoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Empoli Defeat vs Napoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Last 5 Napoli Home Matches
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| 2024 3 November | | Serie A | Napoli | 0 - 3 | Atalanta |
| 2024 26 October | | Serie A | Napoli | 1 - 0 | Lecce |
| 2024 4 October | | Serie A | Napoli | 3 - 1 | Como |
| 2024 29 September | | Serie A | Napoli | 2 - 0 | Monza |
| 2024 26 September | | Cup | Napoli | 5 - 0 | Palermo |
Last 5 Empoli Home Matches
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| 2024 4 November | | Serie A | Empoli | 1 - 0 | Como |
| 2024 30 October | | Serie A | Empoli | 0 - 3 | Internazionale |
| 2024 20 October | | Serie A | Empoli | 0 - 1 | Napoli |
| 2024 29 September | | Serie A | Empoli | 0 - 0 | Fiorentina |
| 2024 14 September | | Serie A | Empoli | 0 - 0 | Juventus |
Last 5 Napoli Away Matches
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| 2024 10 November | | Serie A | Internazionale | 1 - 1 | Napoli |
| 2024 29 October | | Serie A | Milan | 0 - 2 | Napoli |
| 2024 20 October | | Serie A | Empoli | 0 - 1 | Napoli |
| 2024 21 September | | Serie A | Juventus | 0 - 0 | Napoli |
| 2024 15 September | | Serie A | Cagliari | 0 - 4 | Napoli |
Last 5 Empoli Away Matches
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| 2024 8 November | | Serie A | Lecce | 1 - 1 | Empoli |
| 2024 27 October | | Serie A | Parma | 1 - 1 | Empoli |
| 2024 6 October | | Serie A | Lazio | 2 - 1 | Empoli |
| 2024 24 September | | Cup | Torino | 1 - 2 | Empoli |
| 2024 20 September | | Serie A | Cagliari | 0 - 2 | Empoli |