This page lists the head-to-head record of Empoli vs Napoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Napoli | Empoli | Draws |
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| Total Matches | 16 | 6 | 6 | 4 |
| At Stadio San Paolo | 8 | 1 | 5 | 2 |
| At Stadio Carlo Castellani | 8 | 5 | 1 | 2 |
| Serie B Matches | 4 | 1 | 2 | 1 |
| Serie A Matches | 12 | 5 | 4 | 3 |
| Total Goals Scored | 55 | 27 | 28 | |
Last 50 Napoli vs Empoli Matches
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| 2019 3 April | | Serie A | Empoli | 2 - 1 | Napoli |
| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
| 2017 19 March | | Serie A | Empoli | 2 - 3 | Napoli |
| 2016 26 October | | Serie A | Napoli | 2 - 0 | Empoli |
| 2016 31 January | | Serie A | Napoli | 5 - 1 | Empoli |
| 2015 13 September | | Serie A | Empoli | 2 - 2 | Napoli |
| 2015 30 April | | Serie A | Empoli | 4 - 2 | Napoli |
| 2014 7 December | | Serie A | Napoli | 2 - 2 | Empoli |
| 2008 17 February | | Serie A | Napoli | 1 - 3 | Empoli |
| 2007 23 September | | Serie A | Empoli | 0 - 0 | Napoli |
| 2002 17 February | | Serie B | Napoli | 0 - 0 | Empoli |
| 2001 22 September | | Serie B | Empoli | 1 - 0 | Napoli |
| 2000 7 May | | Serie B | Empoli | 4 - 1 | Napoli |
| 1999 4 December | | Serie B | Napoli | 1 - 0 | Empoli |
| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
| 1997 13 September | | Serie A | Napoli | 2 - 1 | Empoli |
Biggest Napoli Victory vs Empoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Biggest Empoli Victory vs Napoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Napoli Defeat vs Empoli
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| 1998 7 February | | Serie A | Empoli | 5 - 0 | Napoli |
Biggest Empoli Defeat vs Napoli
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| 2018 2 November | | Serie A | Napoli | 5 - 1 | Empoli |
Last 5 Napoli Home Matches
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| 2020 29 February | | Serie A | Napoli | 2 - 1 | Torino |
| 2020 25 February | | UEFA Champions League | Napoli | 1 - 1 | Barcelona |
| 2020 9 February | | Serie A | Napoli | 2 - 3 | Lecce |
| 2020 26 January | | Serie A | Napoli | 2 - 1 | Juventus |
| 2020 21 January | | Cup | Napoli | 1 - 0 | Lazio |
Last 5 Empoli Home Matches
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| 2020 7 March | | Serie B | Empoli | 1 - 1 | Trapani |
| 2020 29 February | | Serie B | Empoli | 0 - 1 | Pordenone |
| 2020 16 February | | Serie B | Empoli | 2 - 1 | Pisa |
| 2020 1 February | | Serie B | Empoli | 3 - 1 | Crotone |
| 2020 24 January | | Serie B | Empoli | 1 - 1 | Chievo |
Last 5 Napoli Away Matches
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| 2020 21 February | | Serie A | Brescia | 1 - 2 | Napoli |
| 2020 16 February | | Serie A | Cagliari | 0 - 1 | Napoli |
| 2020 12 February | | Cup | Internazionale | 0 - 1 | Napoli |
| 2020 3 February | | Serie A | Sampdoria | 2 - 4 | Napoli |
| 2020 11 January | | Serie A | Lazio | 1 - 0 | Napoli |
Last 5 Empoli Away Matches
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| 2020 3 March | | Serie B | Cremonese | 2 - 3 | Empoli |
| 2020 24 February | | Serie B | Perugia | 0 - 1 | Empoli |
| 2020 8 February | | Serie B | Cittadella | 1 - 2 | Empoli |
| 2020 18 January | | Serie B | Juve Stabia | 1 - 0 | Empoli |
| 2019 26 December | | Serie B | Cosenza | 1 - 0 | Empoli |