This page lists the head-to-head record of Bayer Leverkusen vs MSV Duisburg including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | MSV Duisburg | Bayer Leverkusen | Draws |
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| Total Matches | 25 | 3 | 15 | 7 |
| At Schauinsland-Reisen-Arena | 12 | 0 | 10 | 2 |
| At BayArena | 13 | 3 | 5 | 5 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Bundesliga Matches | 24 | 3 | 15 | 6 |
| Total Goals Scored | 78 | 30 | 48 | |
Last 50 MSV Duisburg vs Bayer Leverkusen Matches
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| 2008 4 May | | Bundesliga | MSV Duisburg | 3 - 2 | Bayer Leverkusen |
| 2007 24 November | | Bundesliga | Bayer Leverkusen | 4 - 1 | MSV Duisburg |
| 2006 24 October | | Cup | MSV Duisburg | 2 - 2 | Bayer Leverkusen |
| 2006 17 February | | Bundesliga | Bayer Leverkusen | 3 - 2 | MSV Duisburg |
| 2005 17 September | | Bundesliga | MSV Duisburg | 1 - 3 | Bayer Leverkusen |
| 2000 4 February | | Bundesliga | Bayer Leverkusen | 3 - 0 | MSV Duisburg |
| 1999 12 August | | Bundesliga | MSV Duisburg | 0 - 0 | Bayer Leverkusen |
| 1999 14 May | | Bundesliga | MSV Duisburg | 0 - 0 | Bayer Leverkusen |
| 1998 27 November | | Bundesliga | Bayer Leverkusen | 2 - 0 | MSV Duisburg |
| 1998 12 March | | Bundesliga | MSV Duisburg | 1 - 1 | Bayer Leverkusen |
| 1997 3 October | | Bundesliga | Bayer Leverkusen | 2 - 1 | MSV Duisburg |
| 1997 21 February | | Bundesliga | Bayer Leverkusen | 1 - 0 | MSV Duisburg |
| 1996 20 August | | Bundesliga | MSV Duisburg | 1 - 3 | Bayer Leverkusen |
| 1995 21 April | | Bundesliga | Bayer Leverkusen | 2 - 0 | MSV Duisburg |
| 1994 21 October | | Bundesliga | MSV Duisburg | 0 - 2 | Bayer Leverkusen |
| 1993 26 November | | Bundesliga | Bayer Leverkusen | 2 - 1 | MSV Duisburg |
| 1993 6 August | | Bundesliga | MSV Duisburg | 2 - 2 | Bayer Leverkusen |
| 1992 8 February | | Bundesliga | MSV Duisburg | 1 - 2 | Bayer Leverkusen |
| 1991 20 August | | Bundesliga | Bayer Leverkusen | 2 - 1 | MSV Duisburg |
| 1982 7 May | | Bundesliga | Bayer Leverkusen | 2 - 1 | MSV Duisburg |
| 1981 13 November | | Bundesliga | MSV Duisburg | 2 - 1 | Bayer Leverkusen |
| 1981 5 June | | Bundesliga | MSV Duisburg | 2 - 4 | Bayer Leverkusen |
| 1980 5 December | | Bundesliga | Bayer Leverkusen | 1 - 1 | MSV Duisburg |
| 1980 1 February | | Bundesliga | Bayer Leverkusen | 2 - 2 | MSV Duisburg |
| 1979 27 August | | Bundesliga | MSV Duisburg | 5 - 0 | Bayer Leverkusen |
Biggest MSV Duisburg Victory vs Bayer Leverkusen
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| 1979 27 August | | Bundesliga | MSV Duisburg | 5 - 0 | Bayer Leverkusen |
Biggest Bayer Leverkusen Victory vs MSV Duisburg
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| 2007 24 November | | Bundesliga | Bayer Leverkusen | 4 - 1 | MSV Duisburg |
Biggest MSV Duisburg Defeat vs Bayer Leverkusen
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| 2007 24 November | | Bundesliga | Bayer Leverkusen | 4 - 1 | MSV Duisburg |
Biggest Bayer Leverkusen Defeat vs MSV Duisburg
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| 1979 27 August | | Bundesliga | MSV Duisburg | 5 - 0 | Bayer Leverkusen |
Last 5 MSV Duisburg Home Matches
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| 2026 24 January | | 3 Liga | MSV Duisburg | 2 - 0 | Jahn Regensburg |
| 2025 13 December | | 3 Liga | MSV Duisburg | 0 - 0 | Erzgebirge Aue |
| 2025 29 November | | 3 Liga | MSV Duisburg | 3 - 1 | Alemannia Aachen |
| 2025 7 November | | 3 Liga | MSV Duisburg | 2 - 1 | Waldhof Mannheim |
| 2025 26 October | | 3 Liga | MSV Duisburg | 1 - 1 | Rot-Weiss Essen |
Last 5 Bayer Leverkusen Home Matches
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| 2026 28 January | | UEFA Champions League | Bayer Leverkusen | 3 - 0 | Villarreal |
| 2026 24 January | | Bundesliga | Bayer Leverkusen | 1 - 0 | Werder Bremen |
| 2026 10 January | | Bundesliga | Bayer Leverkusen | 1 - 4 | Stuttgart |
| 2025 13 December | | Bundesliga | Bayer Leverkusen | 2 - 0 | FC Koln |
| 2025 10 December | | UEFA Champions League | Bayer Leverkusen | 2 - 2 | Newcastle United |
Last 5 MSV Duisburg Away Matches
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| 2026 18 January | | 3 Liga | Stuttgart II | 0 - 4 | MSV Duisburg |
| 2025 21 December | | 3 Liga | Viktoria Koln | 0 - 0 | MSV Duisburg |
| 2025 6 December | | 3 Liga | Energie Cottbus | 3 - 2 | MSV Duisburg |
| 2025 21 November | | 3 Liga | Hoffenheim II | 4 - 1 | MSV Duisburg |
| 2025 1 November | | 3 Liga | Osnabruck | 0 - 0 | MSV Duisburg |
Last 5 Bayer Leverkusen Away Matches
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| 2026 20 January | | UEFA Champions League | Olympiakos Piraeus | 2 - 0 | Bayer Leverkusen |
| 2026 17 January | | Bundesliga | Hoffenheim | 1 - 0 | Bayer Leverkusen |
| 2025 20 December | | Bundesliga | RB Leipzig | 1 - 3 | Bayer Leverkusen |
| 2025 6 December | | Bundesliga | Augsburg | 2 - 0 | Bayer Leverkusen |
| 2025 2 December | | Cup | Borussia Dortmund | 0 - 1 | Bayer Leverkusen |