This page lists the head-to-head record of Istres vs Lyon including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Lyon | Istres | Draws |
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| Total Matches | 2 | 1 | 0 | 1 |
| At Parc OL | 1 | 0 | 0 | 1 |
| At Stade Parsemain | 1 | 1 | 0 | 0 |
| Ligue 1 Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 3 | 2 | 1 | |
Last 50 Lyon vs Istres Matches
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
| 2004 22 October | | Ligue 1 | Istres | 0 - 0 | Olympique Lyonnais |
Biggest Lyon Victory vs Istres
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
Biggest Istres Defeat vs Lyon
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
Last 5 Lyon Home Matches
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| 2026 8 March | | Ligue 1 | Olympique Lyonnais | 1 - 1 | Paris |
| 2026 5 March | | Cup | Olympique Lyonnais | 2 - 2 | Lens |
| 2026 15 February | | Ligue 1 | Olympique Lyonnais | 2 - 0 | Nice |
| 2026 4 February | | Cup | Olympique Lyonnais | 2 - 0 | Laval |
| 2026 1 February | | Ligue 1 | Olympique Lyonnais | 1 - 0 | Lille |
Last 5 Istres Home Matches
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| 2026 14 March | | CFA | Istres | 1 - 2 | Saint-Priest |
| 2026 21 February | | CFA | Istres | 1 - 1 | Cannes |
| 2026 7 February | | CFA | Istres | 0 - 1 | St Maur Lusitanos |
| 2026 17 January | | CFA | Istres | 2 - 0 | Nimes |
| 2026 10 January | | Cup | Istres | 0 - 2 | Laval |
Last 5 Lyon Away Matches
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| 2026 15 March | | Ligue 1 | Le Havre | 0 - 0 | Olympique Lyonnais |
| 2026 12 March | | UEFA Europa League | Celta Vigo | 1 - 1 | Olympique Lyonnais |
| 2026 1 March | | Ligue 1 | Olympique Marseille | 3 - 2 | Olympique Lyonnais |
| 2026 22 February | | Ligue 1 | Strasbourg | 3 - 1 | Olympique Lyonnais |
| 2026 7 February | | Ligue 1 | Nantes | 0 - 1 | Olympique Lyonnais |
Last 5 Istres Away Matches
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| 2026 6 March | | CFA | Andrezieux ASF | 3 - 1 | Istres |
| 2026 14 February | | CFA | Hyeres FC | 0 - 1 | Istres |
| 2026 30 January | | CFA | Creteil | 1 - 2 | Istres |
| 2026 24 January | | CFA | Rousset-Ste Victoire | 0 - 1 | Istres |
| 2025 20 December | | Cup | SA Merignac | 0 - 0 | Istres |