This page lists the head-to-head record of Istres vs Lyon including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Lyon | Istres | Draws |
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| Total Matches | 2 | 1 | 0 | 1 |
| At Parc OL | 1 | 0 | 0 | 1 |
| At Stade Parsemain | 1 | 1 | 0 | 0 |
| Ligue 1 Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 3 | 2 | 1 | |
Last 50 Lyon vs Istres Matches
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
| 2004 22 October | | Ligue 1 | Istres | 0 - 0 | Olympique Lyonnais |
Biggest Lyon Victory vs Istres
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
Biggest Istres Defeat vs Lyon
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| 2005 11 March | | Ligue 1 | Olympique Lyonnais | 2 - 1 | Istres |
Last 5 Lyon Home Matches
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| 2026 17 May | | Ligue 1 | Olympique Lyonnais | 0 - 4 | Lens |
| 2026 3 May | | Ligue 1 | Olympique Lyonnais | 4 - 2 | Stade Rennes |
| 2026 25 April | | Ligue 1 | Olympique Lyonnais | 3 - 2 | Auxerre |
| 2026 12 April | | Ligue 1 | Olympique Lyonnais | 2 - 0 | Lorient |
| 2026 22 March | | Ligue 1 | Olympique Lyonnais | 1 - 2 | Monaco |
Last 5 Istres Home Matches
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| 2026 16 May | | CFA | Istres | 1 - 2 | Monts d'Or Azergues |
| 2026 1 May | | CFA | Istres | 0 - 0 | Creteil |
| 2026 17 April | | CFA | Istres | 1 - 0 | Bobigny |
| 2026 3 April | | CFA | Istres | 4 - 0 | Frejus St-Raphael |
| 2026 21 March | | CFA | Istres | 0 - 1 | Limonest |
Last 5 Lyon Away Matches
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| 2026 10 May | | Ligue 1 | Toulouse | 2 - 1 | Olympique Lyonnais |
| 2026 19 April | | Ligue 1 | Paris St Germain | 1 - 2 | Olympique Lyonnais |
| 2026 5 April | | Ligue 1 | Angers SCO | 0 - 0 | Olympique Lyonnais |
| 2026 15 March | | Ligue 1 | Le Havre | 0 - 0 | Olympique Lyonnais |
| 2026 12 March | | UEFA Europa League | Celta Vigo | 1 - 1 | Olympique Lyonnais |
Last 5 Istres Away Matches
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| 2026 9 May | | CFA | Nimes | 3 - 0 | Istres |
| 2026 25 April | | CFA | Grasse | 2 - 2 | Istres |
| 2026 11 April | | CFA | Toulon | 2 - 2 | Istres |
| 2026 28 March | | CFA | Rumilly Vallieres | 1 - 1 | Istres |
| 2026 6 March | | CFA | Andrezieux ASF | 3 - 1 | Istres |