This page lists the head-to-head record of Sassuolo vs Lecce including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Lecce | Sassuolo | Draws |
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| Total Matches | 10 | 1 | 4 | 5 |
| At Stadio Via del Mare | 4 | 1 | 2 | 1 |
| At Mapei Stadium | 6 | 0 | 2 | 4 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Serie B Matches | 2 | 0 | 0 | 2 |
| Serie A Matches | 7 | 1 | 3 | 3 |
| Total Goals Scored | 21 | 9 | 12 | |
Last 50 Lecce vs Sassuolo Matches
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| 2025 18 October | | Serie A | Lecce | 0 - 0 | Sassuolo |
| 2024 24 September | | Cup | Lecce | 0 - 2 | Sassuolo |
| 2024 21 April | | Serie A | Sassuolo | 0 - 3 | Lecce |
| 2023 6 October | | Serie A | Lecce | 1 - 1 | Sassuolo |
| 2023 25 February | | Serie A | Lecce | 0 - 1 | Sassuolo |
| 2022 20 August | | Serie A | Sassuolo | 1 - 0 | Lecce |
| 2020 4 July | | Serie A | Sassuolo | 4 - 2 | Lecce |
| 2019 3 November | | Serie A | Lecce | 2 - 2 | Sassuolo |
| 2010 30 May | | Serie B | Lecce | 0 - 0 | Sassuolo |
| 2010 9 January | | Serie B | Sassuolo | 1 - 1 | Lecce |
Biggest Lecce Victory vs Sassuolo
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| 2024 21 April | | Serie A | Sassuolo | 0 - 3 | Lecce |
Biggest Sassuolo Victory vs Lecce
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| 2024 24 September | | Cup | Lecce | 0 - 2 | Sassuolo |
Biggest Lecce Defeat vs Sassuolo
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| 2024 24 September | | Cup | Lecce | 0 - 2 | Sassuolo |
Biggest Sassuolo Defeat vs Lecce
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| 2024 21 April | | Serie A | Sassuolo | 0 - 3 | Lecce |
Last 5 Lecce Home Matches
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| 2025 18 October | | Serie A | Lecce | 0 - 0 | Sassuolo |
| 2025 28 September | | Serie A | Lecce | 2 - 2 | Bologna |
| 2025 19 September | | Serie A | Lecce | 1 - 2 | Cagliari |
| 2025 29 August | | Serie A | Lecce | 0 - 2 | Milan |
| 2025 15 August | | Cup | Lecce | 2 - 0 | Juve Stabia |
Last 5 Sassuolo Home Matches
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| 2025 26 October | | Serie A | Sassuolo | 0 - 1 | Roma |
| 2025 28 September | | Serie A | Sassuolo | 3 - 1 | Udinese |
| 2025 14 September | | Serie A | Sassuolo | 1 - 0 | Lazio |
| 2025 23 August | | Serie A | Sassuolo | 0 - 2 | Napoli |
| 2025 15 August | | Cup | Sassuolo | 1 - 0 | Catanzaro |
Last 5 Lecce Away Matches
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| 2025 25 October | | Serie A | Udinese | 3 - 2 | Lecce |
| 2025 4 October | | Serie A | Parma | 0 - 1 | Lecce |
| 2025 23 September | | Cup | Milan | 3 - 0 | Lecce |
| 2025 14 September | | Serie A | Atalanta | 4 - 1 | Lecce |
| 2025 23 August | | Serie A | Genoa | 0 - 0 | Lecce |
Last 5 Sassuolo Away Matches
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| 2025 18 October | | Serie A | Lecce | 0 - 0 | Sassuolo |
| 2025 3 October | | Serie A | Hellas Verona | 0 - 1 | Sassuolo |
| 2025 24 September | | Cup | Como | 3 - 0 | Sassuolo |
| 2025 21 September | | Serie A | Internazionale | 2 - 1 | Sassuolo |
| 2025 29 August | | Serie A | Cremonese | 3 - 2 | Sassuolo |