This page lists the head-to-head record of Siena vs Lazio including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Lazio | Siena | Draws |
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| Total Matches | 19 | 6 | 6 | 7 |
| At Stadio Olimpico | 9 | 1 | 6 | 2 |
| At Montepaschi Arena | 10 | 5 | 0 | 5 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Serie A Matches | 18 | 6 | 6 | 6 |
| Total Goals Scored | 55 | 26 | 29 | |
Last 50 Lazio vs Siena Matches
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| 2013 18 February | | Serie A | Robur Siena | 3 - 0 | Lazio |
| 2012 19 December | | Cup | Lazio | 1 - 1 | Robur Siena |
| 2012 30 September | | Serie A | Lazio | 2 - 1 | Robur Siena |
| 2012 2 May | | Serie A | Lazio | 1 - 1 | Robur Siena |
| 2012 7 January | | Serie A | Robur Siena | 4 - 0 | Lazio |
| 2010 24 March | | Serie A | Lazio | 2 - 0 | Robur Siena |
| 2009 1 November | | Serie A | Robur Siena | 1 - 1 | Lazio |
| 2009 5 April | | Serie A | Robur Siena | 2 - 0 | Lazio |
| 2008 9 November | | Serie A | Lazio | 3 - 0 | Robur Siena |
| 2008 13 April | | Serie A | Lazio | 1 - 1 | Robur Siena |
| 2007 2 December | | Serie A | Robur Siena | 1 - 1 | Lazio |
| 2007 27 May | | Serie A | Robur Siena | 2 - 1 | Lazio |
| 2007 14 January | | Serie A | Lazio | 1 - 1 | Robur Siena |
| 2006 8 April | | Serie A | Robur Siena | 2 - 3 | Lazio |
| 2005 3 December | | Serie A | Lazio | 3 - 2 | Robur Siena |
| 2005 18 March | | Serie A | Robur Siena | 1 - 0 | Lazio |
| 2004 6 November | | Serie A | Lazio | 1 - 1 | Robur Siena |
| 2004 3 April | | Serie A | Lazio | 5 - 2 | Robur Siena |
| 2003 28 November | | Serie A | Robur Siena | 3 - 0 | Lazio |
Biggest Lazio Victory vs Siena
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| 2008 9 November | | Serie A | Lazio | 3 - 0 | Robur Siena |
Biggest Siena Victory vs Lazio
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| 2012 7 January | | Serie A | Robur Siena | 4 - 0 | Lazio |
Biggest Lazio Defeat vs Siena
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| 2012 7 January | | Serie A | Robur Siena | 4 - 0 | Lazio |
Biggest Siena Defeat vs Lazio
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| 2008 9 November | | Serie A | Lazio | 3 - 0 | Robur Siena |
Last 5 Lazio Home Matches
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| 2024 7 November | | UEFA Europa League | Lazio | 2 - 1 | Porto |
| 2024 4 November | | Serie A | Lazio | 2 - 1 | Cagliari |
| 2024 27 October | | Serie A | Lazio | 3 - 0 | Genoa |
| 2024 6 October | | Serie A | Lazio | 2 - 1 | Empoli |
| 2024 3 October | | UEFA Europa League | Lazio | 4 - 1 | Nice |
Last 5 Siena Home Matches
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| 2023 23 April | | Serie C1 - A | Robur Siena | 1 - 2 | Virtus Entella |
| 2023 6 April | | Serie C1 - A | Robur Siena | 2 - 2 | Gubbio |
| 2023 18 March | | Serie C1 - A | Robur Siena | 0 - 0 | Alessandria |
| 2023 11 March | | Serie C1 - A | Robur Siena | 4 - 0 | Vis Pesaro |
| 2023 25 February | | Serie C1 - A | Robur Siena | 1 - 1 | Recanatese |
Last 5 Lazio Away Matches
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| 2024 10 November | | Serie A | Monza | 0 - 1 | Lazio |
| 2024 31 October | | Serie A | Como | 1 - 5 | Lazio |
| 2024 24 October | | UEFA Europa League | Twente | 0 - 2 | Lazio |
| 2024 19 October | | Serie A | Juventus | 1 - 0 | Lazio |
| 2024 29 September | | Serie A | Torino | 2 - 3 | Lazio |
Last 5 Siena Away Matches
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| 2023 15 April | | Serie C1 - A | Fiorenzuola | 1 - 1 | Robur Siena |
| 2023 1 April | | Serie C1 - A | Fermana | 3 - 1 | Robur Siena |
| 2023 26 March | | Serie C1 - A | Carrarese | 3 - 0 | Robur Siena |
| 2023 14 March | | Serie C1 - A | Lucchese | 1 - 1 | Robur Siena |
| 2023 5 March | | Serie C1 - A | San Donato Tavarnelle | 1 - 1 | Robur Siena |