This page lists the head-to-head record of Hoffenheim vs Karlsruhe SC including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Karlsruhe SC | Hoffenheim | Draws |
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| Total Matches | 2 | 0 | 1 | 1 |
| At Wildparkstadion | 1 | 0 | 1 | 0 |
| At Rhein-Neckar-Arena | 1 | 0 | 0 | 1 |
| Bundesliga Matches | 2 | 0 | 1 | 1 |
| Total Goals Scored | 9 | 3 | 6 | |
Last 50 Karlsruhe SC vs Hoffenheim Matches
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| 2009 18 April | | Bundesliga | Karlsruher SC | 2 - 2 | Hoffenheim |
| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Biggest Hoffenheim Victory vs Karlsruhe SC
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| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Biggest Karlsruhe SC Defeat vs Hoffenheim
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| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Last 5 Karlsruhe SC Home Matches
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| 2025 1 November | | Bundesliga 2 | Karlsruher SC | 2 - 1 | Schalke 04 |
| 2025 18 October | | Bundesliga 2 | Karlsruher SC | 2 - 3 | Kaiserslautern |
| 2025 27 September | | Bundesliga 2 | Karlsruher SC | 1 - 0 | Magdeburg |
| 2025 13 September | | Bundesliga 2 | Karlsruher SC | 2 - 1 | Nurnberg |
| 2025 23 August | | Bundesliga 2 | Karlsruher SC | 2 - 0 | Eintracht Braunschweig |
Last 5 Hoffenheim Home Matches
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| 2025 8 November | | Bundesliga | Hoffenheim | 3 - 1 | RB Leipzig |
| 2025 25 October | | Bundesliga | Hoffenheim | 3 - 1 | Heidenheim |
| 2025 3 October | | Bundesliga | Hoffenheim | 0 - 1 | FC Koln |
| 2025 20 September | | Bundesliga | Hoffenheim | 1 - 4 | Bayern Munchen |
| 2025 30 August | | Bundesliga | Hoffenheim | 1 - 3 | Eintracht Frankfurt |
Last 5 Karlsruhe SC Away Matches
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| 2025 8 November | | Bundesliga 2 | Arminia Bielefeld | 4 - 0 | Karlsruher SC |
| 2025 28 October | | Cup | Borussia M'gladbach | 3 - 1 | Karlsruher SC |
| 2025 24 October | | Bundesliga 2 | Greuther Furth | 1 - 4 | Karlsruher SC |
| 2025 4 October | | Bundesliga 2 | Dynamo Dresden | 3 - 3 | Karlsruher SC |
| 2025 21 September | | Bundesliga 2 | Holstein Kiel | 3 - 0 | Karlsruher SC |
Last 5 Hoffenheim Away Matches
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| 2025 2 November | | Bundesliga | Wolfsburg | 2 - 3 | Hoffenheim |
| 2025 28 October | | Cup | St. Pauli | 1 - 1 | Hoffenheim |
| 2025 19 October | | Bundesliga | St. Pauli | 0 - 3 | Hoffenheim |
| 2025 28 September | | Bundesliga | Freiburg | 1 - 1 | Hoffenheim |
| 2025 13 September | | Bundesliga | Union Berlin | 2 - 4 | Hoffenheim |