This page lists the head-to-head record of FSV Mainz vs Karlsruhe SC including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Karlsruhe SC | FSV Mainz | Draws |
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| Total Matches | 11 | 0 | 5 | 6 |
| At Wildparkstadion | 5 | 0 | 2 | 3 |
| At Opel Arena | 6 | 0 | 3 | 3 |
| Bundesliga 2 Matches | 10 | 0 | 5 | 5 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Total Goals Scored | 29 | 10 | 19 | |
Last 50 Karlsruhe SC vs FSV Mainz Matches
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| 2004 20 September | | Cup | Karlsruher SC | 1 - 1 | Mainz 05 |
| 2004 14 March | | Bundesliga 2 | Karlsruher SC | 1 - 1 | Mainz 05 |
| 2003 28 September | | Bundesliga 2 | Mainz 05 | 1 - 1 | Karlsruher SC |
| 2003 10 April | | Bundesliga 2 | Karlsruher SC | 0 - 0 | Mainz 05 |
| 2002 3 November | | Bundesliga 2 | Mainz 05 | 2 - 2 | Karlsruher SC |
| 2002 5 February | | Bundesliga 2 | Karlsruher SC | 1 - 4 | Mainz 05 |
| 2001 18 August | | Bundesliga 2 | Mainz 05 | 1 - 0 | Karlsruher SC |
| 2000 25 March | | Bundesliga 2 | Mainz 05 | 2 - 2 | Karlsruher SC |
| 1999 1 October | | Bundesliga 2 | Karlsruher SC | 1 - 2 | Mainz 05 |
| 1999 25 February | | Bundesliga 2 | Karlsruher SC | 0 - 1 | Mainz 05 |
| 1998 12 August | | Bundesliga 2 | Mainz 05 | 4 - 1 | Karlsruher SC |
Biggest FSV Mainz Victory vs Karlsruhe SC
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| 2002 5 February | | Bundesliga 2 | Karlsruher SC | 1 - 4 | Mainz 05 |
Biggest Karlsruhe SC Defeat vs FSV Mainz
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| 2002 5 February | | Bundesliga 2 | Karlsruher SC | 1 - 4 | Mainz 05 |
Last 5 Karlsruhe SC Home Matches
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| 2024 21 April | | Bundesliga 2 | Karlsruher SC | 3 - 2 | Hertha BSC |
| 2024 6 April | | Bundesliga 2 | Karlsruher SC | 2 - 1 | St. Pauli |
| 2024 17 March | | Bundesliga 2 | Karlsruher SC | 7 - 0 | Magdeburg |
| 2024 2 March | | Bundesliga 2 | Karlsruher SC | 4 - 0 | Greuther Furth |
| 2024 17 February | | Bundesliga 2 | Karlsruher SC | 2 - 2 | Fortuna Dusseldorf |
Last 5 FSV Mainz Home Matches
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| 2024 13 April | | Bundesliga | Mainz 05 | 4 - 1 | Hoffenheim |
| 2024 6 April | | Bundesliga | Mainz 05 | 4 - 0 | Darmstadt 98 |
| 2024 16 March | | Bundesliga | Mainz 05 | 2 - 0 | Bochum |
| 2024 2 March | | Bundesliga | Mainz 05 | 1 - 1 | Borussia M'gladbach |
| 2024 17 February | | Bundesliga | Mainz 05 | 1 - 0 | Augsburg |
Last 5 Karlsruhe SC Away Matches
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| 2024 13 April | | Bundesliga 2 | Paderborn | 1 - 1 | Karlsruher SC |
| 2024 31 March | | Bundesliga 2 | Schalke 04 | 0 - 0 | Karlsruher SC |
| 2024 9 March | | Bundesliga 2 | Holstein Kiel | 1 - 0 | Karlsruher SC |
| 2024 24 February | | Bundesliga 2 | Kaiserslautern | 0 - 4 | Karlsruher SC |
| 2024 10 February | | Bundesliga 2 | Eintracht Braunschweig | 2 - 0 | Karlsruher SC |
Last 5 FSV Mainz Away Matches
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| 2024 21 April | | Bundesliga | Freiburg | 1 - 1 | Mainz 05 |
| 2024 30 March | | Bundesliga | RB Leipzig | 0 - 0 | Mainz 05 |
| 2024 9 March | | Bundesliga | Bayern Munchen | 8 - 1 | Mainz 05 |
| 2024 23 February | | Bundesliga | Bayer Leverkusen | 2 - 1 | Mainz 05 |
| 2024 11 February | | Bundesliga | Stuttgart | 3 - 1 | Mainz 05 |