This page lists the head-to-head record of Panetolikos vs Iraklis including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Iraklis | Panetolikos | Draws |
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| Total Matches | 7 | 2 | 4 | 1 |
| At Kaftanzoglio Stadium | 4 | 1 | 3 | 0 |
| At Panetolikos Pitch | 3 | 1 | 1 | 1 |
| Super League Matches | 4 | 1 | 2 | 1 |
| Cup Matches | 1 | 1 | 0 | 0 |
| BEthiniki Matches | 2 | 0 | 2 | 0 |
| Total Goals Scored | 14 | 4 | 10 | |
Last 50 Iraklis vs Panetolikos Matches
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| 2017 23 April | | Super League | Iraklis | 2 - 1 | Panaitolikos |
| 2016 11 December | | Super League | Panaitolikos | 2 - 0 | Iraklis |
| 2016 17 April | | Super League | Iraklis | 0 - 0 | Panaitolikos |
| 2015 20 December | | Super League | Panaitolikos | 2 - 0 | Iraklis |
| 2013 26 May | | BEthiniki | Iraklis | 0 - 2 | Panaitolikos |
| 2013 11 February | | BEthiniki | Panaitolikos | 3 - 0 | Iraklis |
| 2010 27 October | | Cup | Panaitolikos | 0 - 2 | Iraklis |
Biggest Iraklis Victory vs Panetolikos
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| 2010 27 October | | Cup | Panaitolikos | 0 - 2 | Iraklis |
Biggest Panetolikos Victory vs Iraklis
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| 2013 11 February | | BEthiniki | Panaitolikos | 3 - 0 | Iraklis |
Biggest Iraklis Defeat vs Panetolikos
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| 2013 11 February | | BEthiniki | Panaitolikos | 3 - 0 | Iraklis |
Biggest Panetolikos Defeat vs Iraklis
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| 2010 27 October | | Cup | Panaitolikos | 0 - 2 | Iraklis |
Last 5 Iraklis Home Matches
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| 2019 22 April | | BEthiniki | Iraklis | 2 - 0 | Vo1los NFC |
| 2019 17 April | | BEthiniki | Iraklis | 1 - 0 | Trikala |
| 2019 6 April | | BEthiniki | Iraklis | 0 - 0 | AOX Kissamikos |
| 2019 28 March | | BEthiniki | Iraklis | 0 - 0 | Doxa Dramas |
| 2019 17 March | | BEthiniki | Iraklis | 2 - 1 | Aittitos Spata |
Last 5 Panetolikos Home Matches
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| 2024 9 November | | Super League | Panaitolikos | 2 - 1 | Aris |
| 2024 26 October | | Super League | Panaitolikos | 0 - 1 | Vo1los NFC |
| 2024 5 October | | Super League | Panaitolikos | 1 - 0 | AEK Athens |
| 2024 21 September | | Super League | Panaitolikos | 1 - 1 | Asteras Tripolis |
| 2024 31 August | | Super League | Panaitolikos | 3 - 0 | Panserraikos |
Last 5 Iraklis Away Matches
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| 2019 5 May | | BEthiniki | Platanias | 2 - 1 | Iraklis |
| 2019 13 April | | BEthiniki | Ergotelis | 1 - 1 | Iraklis |
| 2019 31 March | | BEthiniki | Apollon Pontou | 0 - 1 | Iraklis |
| 2019 24 March | | BEthiniki | Karaiskakis | 1 - 0 | Iraklis |
| 2019 10 March | | BEthiniki | Sparta | 0 - 1 | Iraklis |
Last 5 Panetolikos Away Matches
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| 2024 2 November | | Super League | Kallithea | 1 - 1 | Panaitolikos |
| 2024 19 October | | Super League | Atromitos | 0 - 2 | Panaitolikos |
| 2024 29 September | | Super League | OFI | 1 - 2 | Panaitolikos |
| 2024 25 September | | Cup | OFI | 2 - 1 | Panaitolikos |
| 2024 15 September | | Super League | Olympiakos Piraeus | 0 - 0 | Panaitolikos |