This page lists the head-to-head record of Karlsruhe SC vs Hoffenheim including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Hoffenheim | Karlsruhe SC | Draws |
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| Total Matches | 2 | 1 | 0 | 1 |
| At Rhein-Neckar-Arena | 1 | 0 | 0 | 1 |
| At Wildparkstadion | 1 | 1 | 0 | 0 |
| Bundesliga Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 9 | 6 | 3 | |
Last 50 Hoffenheim vs Karlsruhe SC Matches
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| 2009 18 April | | Bundesliga | Karlsruher SC | 2 - 2 | Hoffenheim |
| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Biggest Hoffenheim Victory vs Karlsruhe SC
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| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Biggest Karlsruhe SC Defeat vs Hoffenheim
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| 2008 1 November | | Bundesliga | Hoffenheim | 4 - 1 | Karlsruher SC |
Last 5 Hoffenheim Home Matches
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| 2025 29 March | | Bundesliga | Hoffenheim | 1 - 1 | Augsburg |
| 2025 9 March | | Bundesliga | Hoffenheim | 1 - 1 | Heidenheim |
| 2025 23 February | | Bundesliga | Hoffenheim | 1 - 1 | Stuttgart |
| 2025 8 February | | Bundesliga | Hoffenheim | 0 - 4 | Union Berlin |
| 2025 26 January | | Bundesliga | Hoffenheim | 2 - 2 | Eintracht Frankfurt |
Last 5 Karlsruhe SC Home Matches
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| 2025 16 March | | Bundesliga 2 | Karlsruher SC | 0 - 0 | Ulm |
| 2025 1 March | | Bundesliga 2 | Karlsruher SC | 1 - 0 | FC Koln |
| 2025 22 February | | Bundesliga 2 | Karlsruher SC | 3 - 1 | Magdeburg |
| 2025 9 February | | Bundesliga 2 | Karlsruher SC | 0 - 2 | Eintracht Braunschweig |
| 2025 25 January | | Bundesliga 2 | Karlsruher SC | 2 - 3 | Fortuna Dusseldorf |
Last 5 Hoffenheim Away Matches
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| 2025 14 March | | Bundesliga | St. Pauli | 1 - 0 | Hoffenheim |
| 2025 1 March | | Bundesliga | Bochum | 0 - 1 | Hoffenheim |
| 2025 16 February | | Bundesliga | Werder Bremen | 1 - 3 | Hoffenheim |
| 2025 2 February | | Bundesliga | Bayer Leverkusen | 3 - 1 | Hoffenheim |
| 2025 30 January | | UEFA Europa League | Anderlecht | 3 - 4 | Hoffenheim |
Last 5 Karlsruhe SC Away Matches
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| 2025 29 March | | Bundesliga 2 | Hertha BSC | 3 - 1 | Karlsruher SC |
| 2025 7 March | | Bundesliga 2 | Darmstadt 98 | 3 - 0 | Karlsruher SC |
| 2025 16 February | | Bundesliga 2 | Schalke 04 | 2 - 1 | Karlsruher SC |
| 2025 31 January | | Bundesliga 2 | Elversberg | 2 - 2 | Karlsruher SC |
| 2025 19 January | | Bundesliga 2 | Nurnberg | 2 - 1 | Karlsruher SC |