This page lists the head-to-head record of Sampdoria vs Grosseto including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Grosseto | Sampdoria | Draws |
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| Total Matches | 2 | 0 | 1 | 1 |
| At Stadio Carlo Zecchini | 1 | 0 | 0 | 1 |
| At Luigi Ferraris | 1 | 0 | 1 | 0 |
| Serie B Matches | 2 | 0 | 1 | 1 |
| Total Goals Scored | 1 | 0 | 1 | |
Last 50 Grosseto vs Sampdoria Matches
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
| 2011 17 September | | Serie B | Sampdoria | 0 - 0 | Grosseto |
Biggest Sampdoria Victory vs Grosseto
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
Biggest Grosseto Defeat vs Sampdoria
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| 2012 4 February | | Serie B | Grosseto | 0 - 1 | Sampdoria |
Last 5 Grosseto Home Matches
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| 2022 14 April | | Serie C1 - A | Grosseto | 0 - 2 | Lucchese |
| 2022 3 April | | Serie C1 - A | Grosseto | 0 - 0 | Robur Siena |
| 2022 19 March | | Serie C1 - A | Grosseto | 1 - 0 | Virtus Entella |
| 2022 15 March | | Serie C1 - A | Grosseto | 0 - 0 | Pontedera |
| 2022 6 March | | Serie C1 - A | Grosseto | 2 - 0 | Imolese |
Last 5 Sampdoria Home Matches
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| 2025 25 October | | Serie B | Sampdoria | 1 - 1 | Frosinone |
| 2025 5 October | | Serie B | Sampdoria | 4 - 1 | Pescara |
| 2025 1 October | | Serie B | Sampdoria | 0 - 0 | Catanzaro |
| 2025 13 September | | Serie B | Sampdoria | 1 - 2 | Cesena |
| 2025 25 August | | Serie B | Sampdoria | 0 - 2 | Modena |
Last 5 Grosseto Away Matches
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| 2022 23 April | | Serie C1 - A | Olbia | 3 - 1 | Grosseto |
| 2022 9 April | | Serie C1 - A | Pescara | 2 - 1 | Grosseto |
| 2022 27 March | | Serie C1 - A | Montevarchi Calcio | 1 - 1 | Grosseto |
| 2022 12 March | | Serie C1 - A | Vis Pesaro | 2 - 1 | Grosseto |
| 2022 27 February | | Serie C1 - A | Teramo | 2 - 1 | Grosseto |
Last 5 Sampdoria Away Matches
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| 2025 17 October | | Serie B | Virtus Entella | 3 - 1 | Sampdoria |
| 2025 27 September | | Serie B | Bari 1908 | 1 - 1 | Sampdoria |
| 2025 20 September | | Serie B | Monza | 1 - 0 | Sampdoria |
| 2025 31 August | | Serie B | Sudtirol | 3 - 1 | Sampdoria |
| 2025 18 August | | Cup | Spezia | 1 - 1 | Sampdoria |