This page lists the head-to-head record of FC Twente vs Fortuna Sittard including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Fortuna Sittard | FC Twente | Draws |
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| Total Matches | 24 | 5 | 13 | 6 |
| At Trendwork Arena | 11 | 1 | 7 | 3 |
| At De Grolsch Veste | 13 | 4 | 6 | 3 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Eredivisie Matches | 23 | 5 | 12 | 6 |
| Total Goals Scored | 65 | 23 | 42 | |
Last 50 Fortuna Sittard vs FC Twente Matches
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| 2024 6 April | | Eredivisie | Twente | 2 - 0 | Fortuna Sittard |
| 2023 8 October | | Eredivisie | Fortuna Sittard | 0 - 3 | Twente |
| 2023 11 March | | Eredivisie | Fortuna Sittard | 0 - 3 | Twente |
| 2022 14 August | | Eredivisie | Twente | 3 - 0 | Fortuna Sittard |
| 2022 7 May | | Eredivisie | Twente | 1 - 2 | Fortuna Sittard |
| 2021 14 August | | Eredivisie | Fortuna Sittard | 2 - 1 | Twente |
| 2021 1 May | | Eredivisie | Fortuna Sittard | 3 - 0 | Twente |
| 2020 12 September | | Eredivisie | Twente | 2 - 0 | Fortuna Sittard |
| 2019 15 September | | Eredivisie | Fortuna Sittard | 2 - 3 | Twente |
| 2005 19 September | | Cup | Fortuna Sittard | 1 - 3 | Twente |
| 2002 12 April | | Eredivisie | Fortuna Sittard | 2 - 0 | Twente |
| 2001 30 November | | Eredivisie | Twente | 1 - 1 | Fortuna Sittard |
| 2001 10 May | | Eredivisie | Fortuna Sittard | 0 - 2 | Twente |
| 2000 13 October | | Eredivisie | Twente | 1 - 1 | Fortuna Sittard |
| 2000 17 February | | Eredivisie | Fortuna Sittard | 2 - 2 | Twente |
| 1999 30 November | | Eredivisie | Twente | 1 - 0 | Fortuna Sittard |
| 1999 30 April | | Eredivisie | Twente | 2 - 2 | Fortuna Sittard |
| 1998 29 October | | Eredivisie | Fortuna Sittard | 0 - 3 | Twente |
| 1997 5 December | | Eredivisie | Fortuna Sittard | 1 - 0 | Twente |
| 1997 18 August | | Eredivisie | Twente | 4 - 1 | Fortuna Sittard |
| 1997 2 May | | Eredivisie | Twente | 2 - 1 | Fortuna Sittard |
| 1996 15 November | | Eredivisie | Fortuna Sittard | 1 - 1 | Twente |
| 1996 5 April | | Eredivisie | Twente | 1 - 0 | Fortuna Sittard |
| 1995 3 November | | Eredivisie | Fortuna Sittard | 1 - 1 | Twente |
Biggest Fortuna Sittard Victory vs FC Twente
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| 2021 1 May | | Eredivisie | Fortuna Sittard | 3 - 0 | Twente |
Biggest FC Twente Victory vs Fortuna Sittard
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| 2023 11 March | | Eredivisie | Fortuna Sittard | 0 - 3 | Twente |
Biggest Fortuna Sittard Defeat vs FC Twente
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| 2023 11 March | | Eredivisie | Fortuna Sittard | 0 - 3 | Twente |
Biggest FC Twente Defeat vs Fortuna Sittard
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| 2021 1 May | | Eredivisie | Fortuna Sittard | 3 - 0 | Twente |
Last 5 Fortuna Sittard Home Matches
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| 2024 2 November | | Eredivisie | Fortuna Sittard | 3 - 0 | Heerenveen |
| 2024 26 October | | Eredivisie | Fortuna Sittard | 1 - 0 | Groningen |
| 2024 6 October | | Eredivisie | Fortuna Sittard | 1 - 0 | AZ |
| 2024 22 September | | Eredivisie | Fortuna Sittard | 1 - 3 | PSV |
| 2024 31 August | | Eredivisie | Fortuna Sittard | 0 - 3 | NEC |
Last 5 FC Twente Home Matches
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| 2024 10 November | | Eredivisie | Twente | 2 - 2 | Ajax |
| 2024 27 October | | Eredivisie | Twente | 5 - 0 | Heracles |
| 2024 24 October | | UEFA Europa League | Twente | 0 - 2 | Lazio |
| 2024 3 October | | UEFA Europa League | Twente | 1 - 1 | Fenerbahce |
| 2024 29 September | | Eredivisie | Twente | 1 - 0 | NAC Breda |
Last 5 Fortuna Sittard Away Matches
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| 2024 9 November | | Eredivisie | PEC Zwolle | 3 - 1 | Fortuna Sittard |
| 2024 29 October | | Cup | De Treffers | 1 - 4 | Fortuna Sittard |
| 2024 20 October | | Eredivisie | Willem II | 0 - 0 | Fortuna Sittard |
| 2024 28 September | | Eredivisie | Sparta Rotterdam | 1 - 1 | Fortuna Sittard |
| 2024 18 September | | Eredivisie | Ajax | 5 - 0 | Fortuna Sittard |
Last 5 FC Twente Away Matches
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| 2024 7 November | | UEFA Europa League | Nice | 2 - 2 | Twente |
| 2024 2 November | | Eredivisie | Willem II | 0 - 1 | Twente |
| 2024 19 October | | Eredivisie | RKC Waalwijk | 2 - 2 | Twente |
| 2024 6 October | | Eredivisie | Feyenoord | 2 - 1 | Twente |
| 2024 25 September | | UEFA Europa League | Manchester United | 1 - 1 | Twente |