This page lists the head-to-head record of Cambuur vs FC Twente including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | FC Twente | Cambuur | Draws |
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| Total Matches | 19 | 13 | 1 | 5 |
| At De Grolsch Veste | 9 | 5 | 1 | 3 |
| At Cambuur Stadion | 10 | 8 | 0 | 2 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Eredivisie Matches | 16 | 11 | 1 | 4 |
| Eerste Divisie Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 44 | 33 | 11 | |
Last 50 FC Twente vs Cambuur Matches
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
| 2022 23 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2022 6 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
| 2019 3 May | | Eerste Divisie | Twente | 2 - 2 | Cambuur |
| 2018 14 December | | Eerste Divisie | Cambuur | 0 - 1 | Twente |
| 2018 30 January | | Cup | Twente | 3 - 1 | Cambuur |
| 2016 20 February | | Eredivisie | Twente | 3 - 0 | Cambuur |
| 2015 19 September | | Eredivisie | Cambuur | 0 - 0 | Twente |
| 2015 31 January | | Eredivisie | Twente | 2 - 1 | Cambuur |
| 2014 9 August | | Eredivisie | Cambuur | 1 - 1 | Twente |
| 2014 2 February | | Eredivisie | Twente | 3 - 1 | Cambuur |
| 2013 4 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2000 10 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 1999 16 September | | Eredivisie | Cambuur | 1 - 3 | Twente |
| 1999 16 April | | Eredivisie | Twente | 0 - 0 | Cambuur |
| 1998 18 September | | Eredivisie | Cambuur | 0 - 2 | Twente |
| 1994 7 May | | Eredivisie | Twente | 4 - 1 | Cambuur |
| 1993 9 December | | Eredivisie | Cambuur | 1 - 1 | Twente |
Biggest FC Twente Victory vs Cambuur
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Biggest Cambuur Victory vs FC Twente
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Biggest FC Twente Defeat vs Cambuur
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Biggest Cambuur Defeat vs FC Twente
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Last 5 FC Twente Home Matches
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| 2025 24 April | | Eredivisie | Twente | 1 - 3 | PSV |
| 2025 5 April | | Eredivisie | Twente | 1 - 1 | Fortuna Sittard |
| 2025 16 March | | Eredivisie | Twente | 2 - 6 | Feyenoord |
| 2025 9 March | | Eredivisie | Twente | 1 - 0 | Almere City |
| 2025 23 February | | Eredivisie | Twente | 2 - 0 | NEC |
Last 5 Cambuur Home Matches
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| 2025 25 April | | Eerste Divisie | Cambuur | 2 - 1 | Vitesse |
| 2025 13 April | | Eerste Divisie | Cambuur | 3 - 1 | Utrecht II |
| 2025 28 March | | Eerste Divisie | Cambuur | 3 - 2 | De Graafschap |
| 2025 10 March | | Eerste Divisie | Cambuur | 1 - 0 | Dordrecht |
| 2025 28 February | | Eerste Divisie | Cambuur | 5 - 0 | VVV |
Last 5 FC Twente Away Matches
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| 2025 4 May | | Eredivisie | Sparta Rotterdam | 0 - 2 | Twente |
| 2025 13 April | | Eredivisie | PEC Zwolle | 1 - 1 | Twente |
| 2025 30 March | | Eredivisie | Heracles | 2 - 1 | Twente |
| 2025 1 March | | Eredivisie | Groningen | 1 - 1 | Twente |
| 2025 20 February | | UEFA Europa League | Bodo / Glimt | 3 - 2 | Twente |
Last 5 Cambuur Away Matches
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| 2025 2 May | | Eerste Divisie | ADO Den Haag | 3 - 4 | Cambuur |
| 2025 18 April | | Eerste Divisie | Helmond Sport | 1 - 1 | Cambuur |
| 2025 4 April | | Eerste Divisie | Emmen | 3 - 0 | Cambuur |
| 2025 15 March | | Eerste Divisie | Volendam | 4 - 1 | Cambuur |
| 2025 7 March | | Eerste Divisie | Den Bosch | 0 - 2 | Cambuur |