This page lists the head-to-head record of Cambuur vs FC Twente including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | FC Twente | Cambuur | Draws |
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| Total Matches | 19 | 13 | 1 | 5 |
| At De Grolsch Veste | 9 | 5 | 1 | 3 |
| At Cambuur Stadion | 10 | 8 | 0 | 2 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Eredivisie Matches | 16 | 11 | 1 | 4 |
| Eerste Divisie Matches | 2 | 1 | 0 | 1 |
| Total Goals Scored | 44 | 33 | 11 | |
Last 50 FC Twente vs Cambuur Matches
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
| 2022 23 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2022 6 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
| 2019 3 May | | Eerste Divisie | Twente | 2 - 2 | Cambuur |
| 2018 14 December | | Eerste Divisie | Cambuur | 0 - 1 | Twente |
| 2018 30 January | | Cup | Twente | 3 - 1 | Cambuur |
| 2016 20 February | | Eredivisie | Twente | 3 - 0 | Cambuur |
| 2015 19 September | | Eredivisie | Cambuur | 0 - 0 | Twente |
| 2015 31 January | | Eredivisie | Twente | 2 - 1 | Cambuur |
| 2014 9 August | | Eredivisie | Cambuur | 1 - 1 | Twente |
| 2014 2 February | | Eredivisie | Twente | 3 - 1 | Cambuur |
| 2013 4 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2000 10 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 1999 16 September | | Eredivisie | Cambuur | 1 - 3 | Twente |
| 1999 16 April | | Eredivisie | Twente | 0 - 0 | Cambuur |
| 1998 18 September | | Eredivisie | Cambuur | 0 - 2 | Twente |
| 1994 7 May | | Eredivisie | Twente | 4 - 1 | Cambuur |
| 1993 9 December | | Eredivisie | Cambuur | 1 - 1 | Twente |
Biggest FC Twente Victory vs Cambuur
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Biggest Cambuur Victory vs FC Twente
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Biggest FC Twente Defeat vs Cambuur
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Biggest Cambuur Defeat vs FC Twente
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Last 5 FC Twente Home Matches
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| 2024 10 November | | Eredivisie | Twente | 2 - 2 | Ajax |
| 2024 27 October | | Eredivisie | Twente | 5 - 0 | Heracles |
| 2024 24 October | | UEFA Europa League | Twente | 0 - 2 | Lazio |
| 2024 3 October | | UEFA Europa League | Twente | 1 - 1 | Fenerbahce |
| 2024 29 September | | Eredivisie | Twente | 1 - 0 | NAC Breda |
Last 5 Cambuur Home Matches
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| 2024 8 November | | Eerste Divisie | Cambuur | 1 - 0 | PSV II |
| 2024 21 October | | Eerste Divisie | Cambuur | 2 - 0 | Eindhoven |
| 2024 18 October | | Eerste Divisie | Cambuur | 1 - 2 | Volendam |
| 2024 29 September | | Eerste Divisie | Cambuur | 1 - 3 | Emmen |
| 2024 16 September | | Eerste Divisie | Cambuur | 0 - 0 | Roda JC |
Last 5 FC Twente Away Matches
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| 2024 7 November | | UEFA Europa League | Nice | 2 - 2 | Twente |
| 2024 2 November | | Eredivisie | Willem II | 0 - 1 | Twente |
| 2024 19 October | | Eredivisie | RKC Waalwijk | 2 - 2 | Twente |
| 2024 6 October | | Eredivisie | Feyenoord | 2 - 1 | Twente |
| 2024 25 September | | UEFA Europa League | Manchester United | 1 - 1 | Twente |
Last 5 Cambuur Away Matches
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| 2024 1 November | | Eerste Divisie | AZ II | 2 - 3 | Cambuur |
| 2024 29 October | | Cup | ADO Den Haag | 1 - 4 | Cambuur |
| 2024 26 October | | Eerste Divisie | Excelsior | 0 - 1 | Cambuur |
| 2024 4 October | | Eerste Divisie | VVV | 0 - 1 | Cambuur |
| 2024 23 September | | Eerste Divisie | Utrecht II | 0 - 4 | Cambuur |