This page lists the head-to-head record of Antwerp vs FC Brussels including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | FC Brussels | Antwerp | Draws |
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| Total Matches | 12 | 3 | 3 | 6 |
| At Stade Edmond Machtens | 6 | 1 | 3 | 2 |
| At Bosuilstadion | 6 | 2 | 0 | 4 |
| Second Division Matches | 12 | 3 | 3 | 6 |
| Total Goals Scored | 35 | 15 | 20 | |
Last 50 FC Brussels vs Antwerp Matches
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| 2014 9 March | | Second Division | RWDM Brussels | 1 - 1 | Antwerp |
| 2013 12 October | | Second Division | Antwerp | 4 - 1 | RWDM Brussels |
| 2013 9 February | | Second Division | RWDM Brussels | 0 - 0 | Antwerp |
| 2012 30 September | | Second Division | Antwerp | 2 - 0 | RWDM Brussels |
| 2012 17 March | | Second Division | RWDM Brussels | 1 - 1 | Antwerp |
| 2011 12 November | | Second Division | Antwerp | 2 - 2 | RWDM Brussels |
| 2011 1 April | | Second Division | RWDM Brussels | 1 - 0 | Antwerp |
| 2010 6 November | | Second Division | Antwerp | 1 - 1 | RWDM Brussels |
| 2010 27 January | | Second Division | RWDM Brussels | 3 - 3 | Antwerp |
| 2009 29 August | | Second Division | Antwerp | 1 - 3 | RWDM Brussels |
| 2009 15 February | | Second Division | RWDM Brussels | 1 - 0 | Antwerp |
| 2008 27 September | | Second Division | Antwerp | 5 - 1 | RWDM Brussels |
Biggest FC Brussels Victory vs Antwerp
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| 2009 29 August | | Second Division | Antwerp | 1 - 3 | RWDM Brussels |
Biggest Antwerp Victory vs FC Brussels
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| 2008 27 September | | Second Division | Antwerp | 5 - 1 | RWDM Brussels |
Biggest FC Brussels Defeat vs Antwerp
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| 2008 27 September | | Second Division | Antwerp | 5 - 1 | RWDM Brussels |
Biggest Antwerp Defeat vs FC Brussels
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| 2009 29 August | | Second Division | Antwerp | 1 - 3 | RWDM Brussels |
Last 5 FC Brussels Home Matches
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| 2025 18 October | | Second Division | RWDM Brussels | 3 - 1 | Club Brugge II |
| 2025 24 September | | Second Division | RWDM Brussels | 1 - 2 | Kortrijk |
| 2025 14 September | | Second Division | RWDM Brussels | 5 - 0 | Seraing United |
| 2025 23 August | | Second Division | RWDM Brussels | 0 - 2 | Waasland-Beveren |
| 2025 9 August | | Second Division | RWDM Brussels | 3 - 3 | Lommel United |
Last 5 Antwerp Home Matches
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| 2025 26 October | | Pro League | Antwerp | 0 - 1 | Club Brugge |
| 2025 4 October | | Pro League | Antwerp | 1 - 1 | Cercle Brugge |
| 2025 14 September | | Pro League | Antwerp | 1 - 2 | Gent |
| 2025 24 August | | Pro League | Antwerp | 2 - 1 | Mechelen |
| 2025 10 August | | Pro League | Antwerp | 3 - 1 | OH Leuven |
Last 5 FC Brussels Away Matches
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| 2025 25 October | | Second Division | Liege | 4 - 3 | RWDM Brussels |
| 2025 4 October | | Second Division | AS Eupen | 2 - 2 | RWDM Brussels |
| 2025 28 September | | Second Division | KAA Gent II | 0 - 2 | RWDM Brussels |
| 2025 19 September | | Second Division | Lierse Kempenzonen | 2 - 0 | RWDM Brussels |
| 2025 6 September | | Cup | Dessel Sport | 2 - 4 | RWDM Brussels |
Last 5 Antwerp Away Matches
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| 2025 20 October | | Pro League | Standard Liege | 1 - 0 | Antwerp |
| 2025 27 September | | Pro League | Zulte-Waregem | 2 - 0 | Antwerp |
| 2025 20 September | | Pro League | Anderlecht | 0 - 0 | Antwerp |
| 2025 30 August | | Pro League | Westerlo | 2 - 0 | Antwerp |
| 2025 17 August | | Pro League | Sporting Charleroi | 1 - 1 | Antwerp |