This page lists the head-to-head record of Siena vs Empoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Empoli | Siena | Draws |
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| Total Matches | 17 | 7 | 5 | 5 |
| At Stadio Carlo Castellani | 9 | 1 | 4 | 4 |
| At Montepaschi Arena | 8 | 6 | 1 | 1 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Serie B Matches | 8 | 3 | 0 | 5 |
| Serie A Matches | 8 | 3 | 5 | 0 |
| Total Goals Scored | 33 | 16 | 17 | |
Last 50 Empoli vs Siena Matches
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| 2014 1 March | | Serie B | Robur Siena | 1 - 1 | Empoli |
| 2013 24 September | | Serie B | Empoli | 0 - 0 | Robur Siena |
| 2011 12 March | | Serie B | Robur Siena | 0 - 0 | Empoli |
| 2010 18 October | | Serie B | Empoli | 3 - 0 | Robur Siena |
| 2008 17 September | | Cup | Robur Siena | 0 - 2 | Empoli |
| 2008 2 March | | Serie A | Empoli | 0 - 2 | Robur Siena |
| 2007 7 October | | Serie A | Robur Siena | 3 - 0 | Empoli |
| 2007 13 May | | Serie A | Robur Siena | 2 - 0 | Empoli |
| 2006 20 December | | Serie A | Empoli | 1 - 0 | Robur Siena |
| 2006 14 April | | Serie A | Empoli | 2 - 1 | Robur Siena |
| 2005 9 December | | Serie A | Robur Siena | 1 - 0 | Empoli |
| 2004 7 February | | Serie A | Empoli | 1 - 0 | Robur Siena |
| 2003 19 September | | Serie A | Robur Siena | 4 - 0 | Empoli |
| 2002 28 April | | Serie B | Robur Siena | 1 - 1 | Empoli |
| 2001 24 November | | Serie B | Empoli | 2 - 1 | Robur Siena |
| 2001 13 April | | Serie B | Robur Siena | 1 - 1 | Empoli |
| 2000 16 November | | Serie B | Empoli | 2 - 0 | Robur Siena |
Biggest Empoli Victory vs Siena
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| 2010 18 October | | Serie B | Empoli | 3 - 0 | Robur Siena |
Biggest Siena Victory vs Empoli
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| 2003 19 September | | Serie A | Robur Siena | 4 - 0 | Empoli |
Biggest Empoli Defeat vs Siena
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| 2003 19 September | | Serie A | Robur Siena | 4 - 0 | Empoli |
Biggest Siena Defeat vs Empoli
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| 2010 18 October | | Serie B | Empoli | 3 - 0 | Robur Siena |
Last 5 Empoli Home Matches
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| 2024 20 April | | Serie A | Empoli | 1 - 0 | Napoli |
| 2024 6 April | | Serie A | Empoli | 3 - 2 | Torino |
| 2024 15 March | | Serie A | Empoli | 0 - 1 | Bologna |
| 2024 3 March | | Serie A | Empoli | 0 - 1 | Cagliari |
| 2024 18 February | | Serie A | Empoli | 1 - 1 | Fiorentina |
Last 5 Siena Home Matches
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| 2023 23 April | | Serie C1 - A | Robur Siena | 1 - 2 | Virtus Entella |
| 2023 6 April | | Serie C1 - A | Robur Siena | 2 - 2 | Gubbio |
| 2023 18 March | | Serie C1 - A | Robur Siena | 0 - 0 | Alessandria |
| 2023 11 March | | Serie C1 - A | Robur Siena | 4 - 0 | Vis Pesaro |
| 2023 25 February | | Serie C1 - A | Robur Siena | 1 - 1 | Recanatese |
Last 5 Empoli Away Matches
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| 2024 13 April | | Serie A | Lecce | 1 - 0 | Empoli |
| 2024 1 April | | Serie A | Internazionale | 2 - 0 | Empoli |
| 2024 10 March | | Serie A | Milan | 1 - 0 | Empoli |
| 2024 24 February | | Serie A | Sassuolo | 2 - 3 | Empoli |
| 2024 9 February | | Serie A | Salernitana | 1 - 3 | Empoli |
Last 5 Siena Away Matches
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| 2023 15 April | | Serie C1 - A | Fiorenzuola | 1 - 1 | Robur Siena |
| 2023 1 April | | Serie C1 - A | Fermana | 3 - 1 | Robur Siena |
| 2023 26 March | | Serie C1 - A | Carrarese | 3 - 0 | Robur Siena |
| 2023 14 March | | Serie C1 - A | Lucchese | 1 - 1 | Robur Siena |
| 2023 5 March | | Serie C1 - A | San Donato Tavarnelle | 1 - 1 | Robur Siena |