This page lists the head-to-head record of FC Twente vs Den Bosch including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Den Bosch | FC Twente | Draws |
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| Total Matches | 9 | 3 | 5 | 1 |
| At de Vliert | 5 | 1 | 4 | 0 |
| At De Grolsch Veste | 4 | 2 | 1 | 1 |
| Cup Matches | 1 | 1 | 0 | 0 |
| Eredivisie Matches | 6 | 1 | 4 | 1 |
| Eerste Divisie Matches | 2 | 1 | 1 | 0 |
| Total Goals Scored | 25 | 8 | 17 | |
Last 50 Den Bosch vs FC Twente Matches
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| 2019 29 March | | Eerste Divisie | Twente | 1 - 0 | Den Bosch |
| 2018 9 November | | Eerste Divisie | Den Bosch | 2 - 1 | Twente |
| 2012 1 November | | Cup | Twente | 1 - 2 | Den Bosch |
| 2005 6 May | | Eredivisie | Den Bosch | 1 - 0 | Twente |
| 2004 3 December | | Eredivisie | Twente | 4 - 0 | Den Bosch |
| 2002 7 February | | Eredivisie | Twente | 4 - 0 | Den Bosch |
| 2001 16 November | | Eredivisie | Den Bosch | 1 - 3 | Twente |
| 2000 12 February | | Eredivisie | Den Bosch | 0 - 0 | Twente |
| 1999 1 October | | Eredivisie | Twente | 3 - 2 | Den Bosch |
Biggest Den Bosch Victory vs FC Twente
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| 2005 6 May | | Eredivisie | Den Bosch | 1 - 0 | Twente |
Biggest FC Twente Victory vs Den Bosch
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| 2004 3 December | | Eredivisie | Twente | 4 - 0 | Den Bosch |
Biggest Den Bosch Defeat vs FC Twente
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| 2004 3 December | | Eredivisie | Twente | 4 - 0 | Den Bosch |
Biggest FC Twente Defeat vs Den Bosch
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| 2005 6 May | | Eredivisie | Den Bosch | 1 - 0 | Twente |
Last 5 Den Bosch Home Matches
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| 2024 2 November | | Eerste Divisie | Den Bosch | 1 - 1 | Roda JC |
| 2024 18 October | | Eerste Divisie | Den Bosch | 4 - 2 | Vitesse |
| 2024 4 October | | Eerste Divisie | Den Bosch | 2 - 2 | De Graafschap |
| 2024 20 September | | Eerste Divisie | Den Bosch | 1 - 0 | Emmen |
| 2024 13 September | | Eerste Divisie | Den Bosch | 2 - 0 | ADO Den Haag |
Last 5 FC Twente Home Matches
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| 2024 10 November | | Eredivisie | Twente | 2 - 2 | Ajax |
| 2024 27 October | | Eredivisie | Twente | 5 - 0 | Heracles |
| 2024 24 October | | UEFA Europa League | Twente | 0 - 2 | Lazio |
| 2024 3 October | | UEFA Europa League | Twente | 1 - 1 | Fenerbahce |
| 2024 29 September | | Eredivisie | Twente | 1 - 0 | NAC Breda |
Last 5 Den Bosch Away Matches
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| 2024 8 November | | Eerste Divisie | TOP Oss | 1 - 0 | Den Bosch |
| 2024 30 October | | Cup | MVV | 2 - 1 | Den Bosch |
| 2024 25 October | | Eerste Divisie | VVV | 1 - 2 | Den Bosch |
| 2024 22 October | | Eerste Divisie | Volendam | 3 - 2 | Den Bosch |
| 2024 28 September | | Eerste Divisie | Telstar | 0 - 0 | Den Bosch |
Last 5 FC Twente Away Matches
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| 2024 7 November | | UEFA Europa League | Nice | 2 - 2 | Twente |
| 2024 2 November | | Eredivisie | Willem II | 0 - 1 | Twente |
| 2024 19 October | | Eredivisie | RKC Waalwijk | 2 - 2 | Twente |
| 2024 6 October | | Eredivisie | Feyenoord | 2 - 1 | Twente |
| 2024 25 September | | UEFA Europa League | Manchester United | 1 - 1 | Twente |