This page lists the head-to-head record of Santa Clara vs CD Nacional including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | CD Nacional | Santa Clara | Draws |
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| Total Matches | 16 | 5 | 6 | 5 |
| At Est·dio da Madeira | 8 | 2 | 4 | 2 |
| At Estadio de Sao Miguel | 8 | 3 | 2 | 3 |
| Division2 Matches | 2 | 1 | 1 | 0 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Portuguese Liga Matches | 9 | 3 | 5 | 1 |
| Segunda Liga Matches | 4 | 1 | 0 | 3 |
| Total Goals Scored | 49 | 21 | 28 | |
Last 50 CD Nacional vs Santa Clara Matches
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| 2026 11 January | | Portuguese Liga | Nacional | 3 - 3 | Santa Clara |
| 2025 30 March | | Portuguese Liga | Santa Clara | 1 - 0 | Nacional |
| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
| 2024 17 March | | Segunda Liga | Santa Clara | 0 - 1 | Nacional |
| 2024 11 January | | Cup | Santa Clara | 0 - 0 | Nacional |
| 2023 4 November | | Segunda Liga | Nacional | 1 - 1 | Santa Clara |
| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
| 2020 6 December | | Portuguese Liga | Nacional | 1 - 3 | Santa Clara |
| 2019 24 February | | Portuguese Liga | Santa Clara | 2 - 0 | Nacional |
| 2018 30 September | | Portuguese Liga | Nacional | 0 - 3 | Santa Clara |
| 2018 15 April | | Segunda Liga | Nacional | 3 - 3 | Santa Clara |
| 2017 3 December | | Segunda Liga | Santa Clara | 1 - 1 | Nacional |
| 2003 18 April | | Portuguese Liga | Nacional | 2 - 1 | Santa Clara |
| 2002 16 November | | Portuguese Liga | Santa Clara | 2 - 3 | Nacional |
| 2001 31 March | | Division2 | Nacional | 2 - 1 | Santa Clara |
| 2000 28 October | | Division2 | Santa Clara | 2 - 1 | Nacional |
Biggest CD Nacional Victory vs Santa Clara
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
Biggest Santa Clara Victory vs CD Nacional
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| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
Biggest CD Nacional Defeat vs Santa Clara
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| 2021 11 April | | Portuguese Liga | Santa Clara | 5 - 1 | Nacional |
Biggest Santa Clara Defeat vs CD Nacional
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| 2024 4 November | | Portuguese Liga | Nacional | 2 - 0 | Santa Clara |
Last 5 CD Nacional Home Matches
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| 2026 25 January | | Portuguese Liga | Nacional | 4 - 0 | Rio Ave |
| 2026 11 January | | Portuguese Liga | Nacional | 3 - 3 | Santa Clara |
| 2025 15 December | | Portuguese Liga | Nacional | 3 - 1 | Tondela |
| 2025 29 November | | Portuguese Liga | Nacional | 1 - 2 | Benfica |
| 2025 1 November | | Portuguese Liga | Nacional | 0 - 1 | Famalicao |
Last 5 Santa Clara Home Matches
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| 2026 18 January | | Portuguese Liga | Santa Clara | 0 - 1 | Famalicao |
| 2026 4 January | | Portuguese Liga | Santa Clara | 0 - 1 | Porto |
| 2025 21 December | | Portuguese Liga | Santa Clara | 0 - 0 | Arouca |
| 2025 18 December | | Cup | Santa Clara | 2 - 2 | Sporting Lisbon |
| 2025 6 December | | Portuguese Liga | Santa Clara | 1 - 0 | Casa Pia |
Last 5 CD Nacional Away Matches
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| 2026 17 January | | Portuguese Liga | Gil Vicente | 2 - 1 | Nacional |
| 2026 2 January | | Portuguese Liga | Guimaraes | 2 - 1 | Nacional |
| 2025 21 December | | Portuguese Liga | AVS | 2 - 2 | Nacional |
| 2025 7 December | | Portuguese Liga | Alverca | 1 - 0 | Nacional |
| 2025 23 November | | Cup | Sporting Braga | 4 - 2 | Nacional |
Last 5 Santa Clara Away Matches
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| 2026 24 January | | Portuguese Liga | Moreirense | 1 - 0 | Santa Clara |
| 2026 11 January | | Portuguese Liga | Nacional | 3 - 3 | Santa Clara |
| 2025 15 December | | Portuguese Liga | Sporting Braga | 1 - 0 | Santa Clara |
| 2025 30 November | | Portuguese Liga | Rio Ave | 1 - 1 | Santa Clara |
| 2025 3 November | | Portuguese Liga | Gil Vicente | 1 - 0 | Santa Clara |