This page lists the head-to-head record of Penafiel vs CD Nacional including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | CD Nacional | Penafiel | Draws |
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| Total Matches | 23 | 11 | 8 | 4 |
| At Est·dio da Madeira | 11 | 5 | 5 | 1 |
| At Estadio Municipal 25 de Abril | 12 | 6 | 3 | 3 |
| Division2 Matches | 6 | 2 | 4 | 0 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Portuguese Liga Matches | 6 | 4 | 2 | 0 |
| Segunda Liga Matches | 10 | 5 | 2 | 3 |
| Total Goals Scored | 65 | 37 | 28 | |
Last 50 CD Nacional vs Penafiel Matches
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| 2024 24 February | | Segunda Liga | Nacional | 3 - 2 | Penafiel |
| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
| 2022 29 October | | Segunda Liga | Nacional | 1 - 1 | Penafiel |
| 2022 13 February | | Segunda Liga | Nacional | 3 - 0 | Penafiel |
| 2021 12 September | | Segunda Liga | Penafiel | 1 - 0 | Nacional |
| 2020 29 February | | Segunda Liga | Penafiel | 1 - 1 | Nacional |
| 2019 21 September | | Segunda Liga | Nacional | 2 - 1 | Penafiel |
| 2018 14 January | | Segunda Liga | Penafiel | 0 - 3 | Nacional |
| 2017 6 August | | Segunda Liga | Nacional | 1 - 1 | Penafiel |
| 2015 26 April | | Portuguese Liga | Nacional | 2 - 0 | Penafiel |
| 2014 13 December | | Portuguese Liga | Penafiel | 2 - 1 | Nacional |
| 2007 20 January | | Cup | Nacional | 0 - 0 | Penafiel |
| 2006 18 February | | Portuguese Liga | Penafiel | 1 - 2 | Nacional |
| 2005 1 October | | Portuguese Liga | Nacional | 2 - 0 | Penafiel |
| 2005 13 May | | Portuguese Liga | Nacional | 1 - 3 | Penafiel |
| 2005 8 January | | Portuguese Liga | Penafiel | 0 - 1 | Nacional |
| 2002 19 January | | Division2 | Nacional | 4 - 1 | Penafiel |
| 2001 18 August | | Division2 | Penafiel | 0 - 2 | Nacional |
| 2001 3 February | | Division2 | Nacional | 0 - 2 | Penafiel |
| 2000 9 September | | Division2 | Penafiel | 3 - 1 | Nacional |
| 1998 2 May | | Division2 | Penafiel | 3 - 2 | Nacional |
| 1998 2 January | | Division2 | Nacional | 1 - 2 | Penafiel |
Biggest CD Nacional Victory vs Penafiel
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| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
Biggest Penafiel Victory vs CD Nacional
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| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
Biggest CD Nacional Defeat vs Penafiel
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| 2023 16 April | | Segunda Liga | Penafiel | 3 - 0 | Nacional |
Biggest Penafiel Defeat vs CD Nacional
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| 2023 2 October | | Segunda Liga | Penafiel | 1 - 4 | Nacional |
Last 5 CD Nacional Home Matches
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| 2025 10 May | | Portuguese Liga | Nacional | 3 - 3 | Rio Ave |
| 2025 3 May | | Portuguese Liga | Nacional | 1 - 2 | Guimaraes |
| 2025 19 April | | Portuguese Liga | Nacional | 0 - 3 | Gil Vicente |
| 2025 6 April | | Portuguese Liga | Nacional | 0 - 1 | Estrela P |
| 2025 16 March | | Portuguese Liga | Nacional | 3 - 1 | Casa Pia |
Last 5 Penafiel Home Matches
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| 2025 15 May | | Segunda Liga | Penafiel | 0 - 0 | Chaves |
| 2025 5 May | | Segunda Liga | Penafiel | 0 - 1 | Torreense |
| 2025 19 April | | Segunda Liga | Penafiel | 1 - 2 | Feirense |
| 2025 29 March | | Segunda Liga | Penafiel | 0 - 1 | Maritimo |
| 2025 8 March | | Segunda Liga | Penafiel | 3 - 2 | Alverca |
Last 5 CD Nacional Away Matches
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| 2025 17 May | | Portuguese Liga | Porto | 3 - 0 | Nacional |
| 2025 27 April | | Portuguese Liga | Moreirense | 1 - 1 | Nacional |
| 2025 12 April | | Portuguese Liga | Boavista | 0 - 1 | Nacional |
| 2025 30 March | | Portuguese Liga | Santa Clara | 1 - 0 | Nacional |
| 2025 8 March | | Portuguese Liga | Benfica | 3 - 0 | Nacional |
Last 5 Penafiel Away Matches
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| 2025 11 May | | Segunda Liga | Benfica II | 1 - 1 | Penafiel |
| 2025 27 April | | Segunda Liga | Leixoes | 3 - 1 | Penafiel |
| 2025 14 April | | Segunda Liga | Mafra | 4 - 2 | Penafiel |
| 2025 5 April | | Segunda Liga | Felgueiras 1932 | 1 - 0 | Penafiel |
| 2025 15 March | | Segunda Liga | Academico Viseu | 1 - 0 | Penafiel |