This page lists the head-to-head record of FC Twente vs Cambuur including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Cambuur | FC Twente | Draws |
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| Total Matches | 19 | 1 | 13 | 5 |
| At Cambuur Stadion | 10 | 0 | 8 | 2 |
| At De Grolsch Veste | 9 | 1 | 5 | 3 |
| Cup Matches | 1 | 0 | 1 | 0 |
| Eredivisie Matches | 16 | 1 | 11 | 4 |
| Eerste Divisie Matches | 2 | 0 | 1 | 1 |
| Total Goals Scored | 44 | 11 | 33 | |
Last 50 Cambuur vs FC Twente Matches
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
| 2022 23 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2022 6 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
| 2019 3 May | | Eerste Divisie | Twente | 2 - 2 | Cambuur |
| 2018 14 December | | Eerste Divisie | Cambuur | 0 - 1 | Twente |
| 2018 30 January | | Cup | Twente | 3 - 1 | Cambuur |
| 2016 20 February | | Eredivisie | Twente | 3 - 0 | Cambuur |
| 2015 19 September | | Eredivisie | Cambuur | 0 - 0 | Twente |
| 2015 31 January | | Eredivisie | Twente | 2 - 1 | Cambuur |
| 2014 9 August | | Eredivisie | Cambuur | 1 - 1 | Twente |
| 2014 2 February | | Eredivisie | Twente | 3 - 1 | Cambuur |
| 2013 4 October | | Eredivisie | Cambuur | 0 - 1 | Twente |
| 2000 10 March | | Eredivisie | Twente | 1 - 0 | Cambuur |
| 1999 16 September | | Eredivisie | Cambuur | 1 - 3 | Twente |
| 1999 16 April | | Eredivisie | Twente | 0 - 0 | Cambuur |
| 1998 18 September | | Eredivisie | Cambuur | 0 - 2 | Twente |
| 1994 7 May | | Eredivisie | Twente | 4 - 1 | Cambuur |
| 1993 9 December | | Eredivisie | Cambuur | 1 - 1 | Twente |
Biggest Cambuur Victory vs FC Twente
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Biggest FC Twente Victory vs Cambuur
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Biggest Cambuur Defeat vs FC Twente
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| 2023 9 April | | Eredivisie | Twente | 4 - 0 | Cambuur |
Biggest FC Twente Defeat vs Cambuur
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| 2021 28 August | | Eredivisie | Cambuur | 2 - 0 | Twente |
Last 5 Cambuur Home Matches
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| 2024 7 December | | Eerste Divisie | Cambuur | 2 - 1 | ADO Den Haag |
| 2024 26 November | | Eerste Divisie | Cambuur | 1 - 2 | Den Bosch |
| 2024 8 November | | Eerste Divisie | Cambuur | 1 - 0 | PSV II |
| 2024 21 October | | Eerste Divisie | Cambuur | 2 - 0 | Eindhoven |
| 2024 18 October | | Eerste Divisie | Cambuur | 1 - 2 | Volendam |
Last 5 FC Twente Home Matches
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| 2024 15 December | | Eredivisie | Twente | 2 - 0 | Groningen |
| 2024 1 December | | Eredivisie | Twente | 3 - 2 | Go Ahead Eagles |
| 2024 28 November | | UEFA Europa League | Twente | 0 - 1 | Union Saint-Gilloise |
| 2024 10 November | | Eredivisie | Twente | 2 - 2 | Ajax |
| 2024 27 October | | Eredivisie | Twente | 5 - 0 | Heracles |
Last 5 Cambuur Away Matches
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| 2024 17 December | | Cup | RKC Waalwijk | 4 - 1 | Cambuur |
| 2024 13 December | | Eerste Divisie | De Graafschap | 0 - 2 | Cambuur |
| 2024 29 November | | Eerste Divisie | Telstar | 2 - 2 | Cambuur |
| 2024 22 November | | Eerste Divisie | Vitesse | 0 - 6 | Cambuur |
| 2024 1 November | | Eerste Divisie | AZ II | 2 - 3 | Cambuur |
Last 5 FC Twente Away Matches
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| 2024 18 December | | Cup | Katwijk | 2 - 3 | Twente |
| 2024 12 December | | UEFA Europa League | Olympiakos Piraeus | 0 - 0 | Twente |
| 2024 6 December | | Eredivisie | PSV | 6 - 1 | Twente |
| 2024 23 November | | Eredivisie | Fortuna Sittard | 1 - 2 | Twente |
| 2024 7 November | | UEFA Europa League | Nice | 2 - 2 | Twente |