This page lists the head-to-head record of SC Paderborn vs Bayer Leverkusen including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Bayer Leverkusen | SC Paderborn | Draws |
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| Total Matches | 6 | 5 | 0 | 1 |
| At BayArena | 2 | 2 | 0 | 0 |
| At Paragon Arena | 4 | 3 | 0 | 1 |
| Cup Matches | 2 | 2 | 0 | 0 |
| Bundesliga Matches | 4 | 3 | 0 | 1 |
| Total Goals Scored | 22 | 16 | 6 | |
Last 50 Bayer Leverkusen vs SC Paderborn Matches
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| 2023 6 December | | Cup | Bayer Leverkusen | 3 - 1 | Paderborn |
| 2020 19 January | | Bundesliga | Paderborn | 1 - 4 | Bayer Leverkusen |
| 2019 29 October | | Cup | Bayer Leverkusen | 1 - 0 | Paderborn |
| 2019 17 August | | Bundesliga | Bayer Leverkusen | 3 - 2 | Paderborn |
| 2015 8 March | | Bundesliga | Paderborn | 0 - 3 | Bayer Leverkusen |
| 2014 4 October | | Bundesliga | Bayer Leverkusen | 2 - 2 | Paderborn |
Biggest Bayer Leverkusen Victory vs SC Paderborn
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| 2020 19 January | | Bundesliga | Paderborn | 1 - 4 | Bayer Leverkusen |
Biggest SC Paderborn Defeat vs Bayer Leverkusen
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| 2020 19 January | | Bundesliga | Paderborn | 1 - 4 | Bayer Leverkusen |
Last 5 Bayer Leverkusen Home Matches
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| 2024 10 December | | UEFA Champions League | Bayer Leverkusen | 1 - 0 | Internazionale |
| 2024 7 December | | Bundesliga | Bayer Leverkusen | 2 - 1 | St. Pauli |
| 2024 26 November | | UEFA Champions League | Bayer Leverkusen | 5 - 0 | Salzburg |
| 2024 23 November | | Bundesliga | Bayer Leverkusen | 5 - 2 | Heidenheim |
| 2024 1 November | | Bundesliga | Bayer Leverkusen | 0 - 0 | Stuttgart |
Last 5 SC Paderborn Home Matches
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| 2024 6 December | | Bundesliga 2 | Paderborn | 2 - 4 | Schalke 04 |
| 2024 22 November | | Bundesliga 2 | Paderborn | 3 - 2 | Nurnberg |
| 2024 3 November | | Bundesliga 2 | Paderborn | 0 - 0 | Eintracht Braunschweig |
| 2024 30 October | | Cup | Paderborn | 0 - 1 | Werder Bremen |
| 2024 4 October | | Bundesliga 2 | Paderborn | 3 - 0 | Jahn Regensburg |
Last 5 Bayer Leverkusen Away Matches
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| 2024 14 December | | Bundesliga | Augsburg | 0 - 2 | Bayer Leverkusen |
| 2024 3 December | | Cup | Bayern Munchen | 0 - 1 | Bayer Leverkusen |
| 2024 30 November | | Bundesliga | Union Berlin | 1 - 2 | Bayer Leverkusen |
| 2024 9 November | | Bundesliga | Bochum | 1 - 1 | Bayer Leverkusen |
| 2024 5 November | | UEFA Champions League | Liverpool | 4 - 0 | Bayer Leverkusen |
Last 5 SC Paderborn Away Matches
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| 2024 14 December | | Bundesliga 2 | Magdeburg | 1 - 1 | Paderborn |
| 2024 30 November | | Bundesliga 2 | Elversberg | 1 - 3 | Paderborn |
| 2024 9 November | | Bundesliga 2 | Fortuna Dusseldorf | 1 - 1 | Paderborn |
| 2024 25 October | | Bundesliga 2 | FC Koln | 1 - 2 | Paderborn |
| 2024 19 October | | Bundesliga 2 | Kaiserslautern | 3 - 0 | Paderborn |