This page lists the head-to-head record of Sampdoria vs Ascoli including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Ascoli | Sampdoria | Draws |
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| Total Matches | 11 | 2 | 4 | 5 |
| At Cino e Lillo del Duca | 6 | 1 | 3 | 2 |
| At Luigi Ferraris | 5 | 1 | 1 | 3 |
| Cup Matches | 1 | 0 | 0 | 1 |
| Serie B Matches | 6 | 0 | 3 | 3 |
| Serie A Matches | 4 | 2 | 1 | 1 |
| Total Goals Scored | 23 | 9 | 14 | |
Last 50 Ascoli vs Sampdoria Matches
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| 2024 11 March | | Serie B | Sampdoria | 2 - 1 | Ascoli Picchio |
| 2023 7 October | | Serie B | Ascoli Picchio | 1 - 1 | Sampdoria |
| 2022 20 October | | Cup | Sampdoria | 1 - 1 | Ascoli Picchio |
| 2012 17 March | | Serie B | Sampdoria | 0 - 0 | Ascoli Picchio |
| 2011 15 October | | Serie B | Ascoli Picchio | 1 - 2 | Sampdoria |
| 2007 11 February | | Serie A | Sampdoria | 2 - 0 | Ascoli Picchio |
| 2006 24 September | | Serie A | Ascoli Picchio | 1 - 1 | Sampdoria |
| 2006 18 February | | Serie A | Sampdoria | 1 - 2 | Ascoli Picchio |
| 2005 15 October | | Serie A | Ascoli Picchio | 2 - 1 | Sampdoria |
| 2003 22 February | | Serie B | Sampdoria | 3 - 0 | Ascoli Picchio |
| 2002 20 September | | Serie B | Ascoli Picchio | 0 - 0 | Sampdoria |
Biggest Ascoli Victory vs Sampdoria
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| 2005 15 October | | Serie A | Ascoli Picchio | 2 - 1 | Sampdoria |
Biggest Sampdoria Victory vs Ascoli
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| 2003 22 February | | Serie B | Sampdoria | 3 - 0 | Ascoli Picchio |
Biggest Ascoli Defeat vs Sampdoria
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| 2003 22 February | | Serie B | Sampdoria | 3 - 0 | Ascoli Picchio |
Biggest Sampdoria Defeat vs Ascoli
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| 2005 15 October | | Serie A | Ascoli Picchio | 2 - 1 | Sampdoria |
Last 5 Ascoli Home Matches
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| 2026 12 February | | Serie C1 - A | Ascoli Picchio | 2 - 2 | Torres |
| 2026 30 January | | Serie C1 - A | Ascoli Picchio | 3 - 1 | Livorno |
| 2026 25 January | | Serie C1 - A | Ascoli Picchio | 2 - 1 | Perugia |
| 2026 9 January | | Serie C1 - A | Ascoli Picchio | 1 - 0 | Ternana |
| 2025 21 December | | Serie C1 - A | Ascoli Picchio | 0 - 0 | Citta di Campobasso |
Last 5 Sampdoria Home Matches
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| 2026 14 February | | Serie B | Sampdoria | 1 - 0 | Calcio Padova |
| 2026 10 February | | Serie B | Sampdoria | 3 - 3 | Palermo |
| 2026 31 January | | Serie B | Sampdoria | 1 - 0 | Spezia |
| 2026 16 January | | Serie B | Sampdoria | 1 - 1 | Virtus Entella |
| 2025 27 December | | Serie B | Sampdoria | 2 - 1 | Reggiana |
Last 5 Ascoli Away Matches
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| 2026 15 February | | Serie C1 - A | Bra | 1 - 3 | Ascoli Picchio |
| 2026 8 February | | Serie C1 - A | Pineto | 1 - 3 | Ascoli Picchio |
| 2026 17 January | | Serie C1 - A | Juventus II | 1 - 0 | Ascoli Picchio |
| 2026 3 January | | Serie C1 - A | Pianese | 4 - 2 | Ascoli Picchio |
| 2025 14 December | | Serie C1 - A | Nuova Monterosi | 0 - 0 | Ascoli Picchio |
Last 5 Sampdoria Away Matches
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| 2026 7 February | | Serie B | Modena | 1 - 2 | Sampdoria |
| 2026 25 January | | Serie B | Catanzaro | 0 - 0 | Sampdoria |
| 2026 10 January | | Serie B | Avellino | 2 - 1 | Sampdoria |
| 2025 20 December | | Serie B | Calcio Padova | 1 - 1 | Sampdoria |
| 2025 12 December | | Serie B | Palermo | 1 - 0 | Sampdoria |