This page lists the head-to-head record of Southampton vs Arsenal including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Arsenal | Southampton | Draws |
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| Total Matches | 99 | 48 | 24 | 27 |
| At Emirates Stadium | 50 | 19 | 20 | 11 |
| At St Mary's Stadium | 49 | 29 | 4 | 16 |
| FA Cup Matches | 3 | 1 | 2 | 0 |
| Carling Cup Matches | 2 | 0 | 2 | 0 |
| Premier League Matches | 94 | 47 | 20 | 27 |
| Total Goals Scored | 275 | 167 | 108 | |
Last 50 Arsenal vs Southampton Matches
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| 2026 4 April | | FA Cup | Southampton | 2 - 1 | Arsenal |
| 2025 25 May | | Premier League | Southampton | 1 - 2 | Arsenal |
| 2024 5 October | | Premier League | Arsenal | 3 - 1 | Southampton |
| 2023 21 April | | Premier League | Arsenal | 3 - 3 | Southampton |
| 2022 23 October | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2022 16 April | | Premier League | Southampton | 1 - 0 | Arsenal |
| 2021 11 December | | Premier League | Arsenal | 3 - 0 | Southampton |
| 2021 26 January | | Premier League | Southampton | 1 - 3 | Arsenal |
| 2021 23 January | | FA Cup | Southampton | 1 - 0 | Arsenal |
| 2020 16 December | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2020 25 June | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2019 23 November | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2019 24 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2018 16 December | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2018 8 April | | Premier League | Arsenal | 3 - 2 | Southampton |
| 2017 10 December | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2017 10 May | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2017 28 January | | FA Cup | Southampton | 0 - 5 | Arsenal |
| 2016 30 November | | Carling Cup | Arsenal | 0 - 2 | Southampton |
| 2016 10 September | | Premier League | Arsenal | 2 - 1 | Southampton |
| 2016 2 February | | Premier League | Arsenal | 0 - 0 | Southampton |
| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
| 2015 1 January | | Premier League | Southampton | 2 - 0 | Arsenal |
| 2014 3 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2014 23 September | | Carling Cup | Arsenal | 1 - 2 | Southampton |
| 2014 28 January | | Premier League | Southampton | 2 - 2 | Arsenal |
| 2013 23 November | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2013 1 January | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2005 25 February | | Premier League | Southampton | 1 - 1 | Arsenal |
| 2004 29 October | | Premier League | Arsenal | 2 - 2 | Southampton |
| 2004 9 February | | Premier League | Arsenal | 2 - 0 | Southampton |
| 2003 28 December | | Premier League | Southampton | 0 - 1 | Arsenal |
| 2003 6 May | | Premier League | Arsenal | 6 - 1 | Southampton |
| 2002 22 November | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2002 1 February | | Premier League | Arsenal | 1 - 1 | Southampton |
| 2001 12 October | | Premier League | Southampton | 0 - 2 | Arsenal |
| 2001 18 May | | Premier League | Southampton | 3 - 2 | Arsenal |
| 2000 1 December | | Premier League | Arsenal | 1 - 0 | Southampton |
| 2000 25 February | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1999 17 September | | Premier League | Southampton | 0 - 1 | Arsenal |
| 1999 2 April | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1998 16 October | | Premier League | Arsenal | 1 - 1 | Southampton |
| 1998 30 January | | Premier League | Arsenal | 3 - 0 | Southampton |
| 1997 22 August | | Premier League | Southampton | 1 - 3 | Arsenal |
| 1997 14 March | | Premier League | Southampton | 0 - 2 | Arsenal |
| 1996 3 December | | Premier League | Arsenal | 3 - 1 | Southampton |
| 1995 8 December | | Premier League | Southampton | 0 - 0 | Arsenal |
| 1995 22 September | | Premier League | Arsenal | 4 - 2 | Southampton |
| 1995 23 January | | Premier League | Arsenal | 1 - 1 | Southampton |
Biggest Arsenal Victory vs Southampton
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Biggest Southampton Victory vs Arsenal
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Biggest Arsenal Defeat vs Southampton
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| 2015 26 December | | Premier League | Southampton | 4 - 0 | Arsenal |
Biggest Southampton Defeat vs Arsenal
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| 2012 15 September | | Premier League | Arsenal | 6 - 1 | Southampton |
Last 5 Arsenal Home Matches
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| 2026 22 March | | Carling Cup | Arsenal | 0 - 2 | Manchester City |
| 2026 17 March | | UEFA Champions League | Arsenal | 2 - 0 | Bayer Leverkusen |
| 2026 14 March | | Premier League | Arsenal | 2 - 0 | Everton |
| 2026 1 March | | Premier League | Arsenal | 2 - 1 | Chelsea |
| 2026 15 February | | FA Cup | Arsenal | 4 - 0 | Wigan Athletic |
Last 5 Southampton Home Matches
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| 2026 4 April | | FA Cup | Southampton | 2 - 1 | Arsenal |
| 2026 21 March | | Championship | Southampton | 2 - 0 | Oxford United |
| 2026 18 March | | Championship | Southampton | 1 - 0 | Norwich City |
| 2026 24 February | | Championship | Southampton | 5 - 0 | Queens Park Rangers |
| 2026 21 February | | Championship | Southampton | 1 - 1 | Charlton Athletic |
Last 5 Arsenal Away Matches
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| 2026 4 April | | FA Cup | Southampton | 2 - 1 | Arsenal |
| 2026 11 March | | UEFA Champions League | Bayer Leverkusen | 1 - 1 | Arsenal |
| 2026 7 March | | FA Cup | Mansfield Town | 1 - 2 | Arsenal |
| 2026 4 March | | Premier League | Brighton & Hove Albion | 0 - 1 | Arsenal |
| 2026 22 February | | Premier League | Tottenham Hotspur | 1 - 4 | Arsenal |
Last 5 Southampton Away Matches
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| 2026 14 March | | Championship | Coventry City | 1 - 2 | Southampton |
| 2026 11 March | | Championship | West Bromwich Albion | 1 - 1 | Southampton |
| 2026 8 March | | FA Cup | Fulham | 0 - 1 | Southampton |
| 2026 28 February | | Championship | Sheffield Wednesday | 1 - 3 | Southampton |
| 2026 10 February | | Championship | Leicester City | 3 - 4 | Southampton |