This page lists the head-to-head record of FC Brussels vs Anderlecht including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Anderlecht | FC Brussels | Draws |
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| Total Matches | 8 | 7 | 0 | 1 |
| At Constant Vanden Stock Stadion | 4 | 3 | 0 | 1 |
| At Stade Edmond Machtens | 4 | 4 | 0 | 0 |
| Pro League Matches | 8 | 7 | 0 | 1 |
| Total Goals Scored | 24 | 21 | 3 | |
Last 50 Anderlecht vs FC Brussels Matches
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| 2008 9 February | | Pro League | RWDM Brussels | 2 - 4 | Anderlecht |
| 2007 25 August | | Pro League | Anderlecht | 3 - 0 | RWDM Brussels |
| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
| 2006 9 December | | Pro League | RWDM Brussels | 0 - 1 | Anderlecht |
| 2006 16 February | | Pro League | Anderlecht | 2 - 0 | RWDM Brussels |
| 2005 16 September | | Pro League | RWDM Brussels | 1 - 1 | Anderlecht |
| 2005 18 March | | Pro League | Anderlecht | 3 - 0 | RWDM Brussels |
| 2004 14 October | | Pro League | RWDM Brussels | 0 - 1 | Anderlecht |
Biggest Anderlecht Victory vs FC Brussels
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| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
Biggest FC Brussels Defeat vs Anderlecht
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| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
Last 5 Anderlecht Home Matches
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| 2026 25 January | | Pro League | Anderlecht | 0 - 0 | Dender |
| 2026 15 January | | Cup | Anderlecht | 1 - 0 | Gent |
| 2025 26 December | | Pro League | Anderlecht | 1 - 2 | Sporting Charleroi |
| 2025 13 December | | Pro League | Anderlecht | 2 - 1 | Sint-Truiden |
| 2025 30 November | | Pro League | Anderlecht | 1 - 0 | Union Saint-Gilloise |
Last 5 FC Brussels Home Matches
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| 2026 31 January | | Second Division | RWDM Brussels | 1 - 0 | KAA Gent II |
| 2026 24 January | | Second Division | RWDM Brussels | 2 - 4 | Patro Eisden |
| 2025 21 December | | Second Division | RWDM Brussels | 0 - 3 | Liege |
| 2025 13 December | | Second Division | RWDM Brussels | 3 - 3 | Olympic Charleroi |
| 2025 29 November | | Second Division | RWDM Brussels | 1 - 3 | Francs Borains |
Last 5 Anderlecht Away Matches
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| 2026 1 February | | Pro League | Standard Liege | 2 - 0 | Anderlecht |
| 2026 18 January | | Pro League | Gent | 4 - 2 | Anderlecht |
| 2025 21 December | | Pro League | Antwerp | 2 - 2 | Anderlecht |
| 2025 7 December | | Pro League | Westerlo | 4 - 0 | Anderlecht |
| 2025 4 December | | Cup | Genk | 1 - 1 | Anderlecht |
Last 5 FC Brussels Away Matches
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| 2026 27 January | | Second Division | KRC Genk II | 0 - 2 | RWDM Brussels |
| 2026 16 January | | Second Division | Seraing United | 3 - 1 | RWDM Brussels |
| 2025 17 December | | Second Division | Club Brugge II | 0 - 1 | RWDM Brussels |
| 2025 6 December | | Second Division | RSC Anderlecht II | 2 - 2 | RWDM Brussels |
| 2025 23 November | | Second Division | Patro Eisden | 1 - 0 | RWDM Brussels |