This page lists the head-to-head record of FC Brussels vs Anderlecht including biggest victories and defeats between the two sides, and H2H stats in all competitions.
Overall H2H Record - Summary
| Total | Anderlecht | FC Brussels | Draws |
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| Total Matches | 8 | 7 | 0 | 1 |
| At Constant Vanden Stock Stadion | 4 | 3 | 0 | 1 |
| At Stade Edmond Machtens | 4 | 4 | 0 | 0 |
| Pro League Matches | 8 | 7 | 0 | 1 |
| Total Goals Scored | 24 | 21 | 3 | |
Last 50 Anderlecht vs FC Brussels Matches
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| 2008 9 February | | Pro League | RWDM Brussels | 2 - 4 | Anderlecht |
| 2007 25 August | | Pro League | Anderlecht | 3 - 0 | RWDM Brussels |
| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
| 2006 9 December | | Pro League | RWDM Brussels | 0 - 1 | Anderlecht |
| 2006 16 February | | Pro League | Anderlecht | 2 - 0 | RWDM Brussels |
| 2005 16 September | | Pro League | RWDM Brussels | 1 - 1 | Anderlecht |
| 2005 18 March | | Pro League | Anderlecht | 3 - 0 | RWDM Brussels |
| 2004 14 October | | Pro League | RWDM Brussels | 0 - 1 | Anderlecht |
Biggest Anderlecht Victory vs FC Brussels
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| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
Biggest FC Brussels Defeat vs Anderlecht
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| 2007 12 May | | Pro League | Anderlecht | 6 - 0 | RWDM Brussels |
Last 5 Anderlecht Home Matches
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| 2025 9 November | | Pro League | Anderlecht | 1 - 0 | Club Brugge |
| 2025 1 November | | Pro League | Anderlecht | 3 - 1 | Mechelen |
| 2025 28 October | | Cup | Anderlecht | 2 - 0 | Ninove |
| 2025 5 October | | Pro League | Anderlecht | 1 - 0 | Standard Liege |
| 2025 23 September | | Pro League | Anderlecht | 1 - 0 | Gent |
Last 5 FC Brussels Home Matches
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| 2025 9 November | | Second Division | RWDM Brussels | 0 - 1 | Beerschot-Wilrijk |
| 2025 1 November | | Second Division | RWDM Brussels | 1 - 1 | KRC Genk II |
| 2025 18 October | | Second Division | RWDM Brussels | 3 - 1 | Club Brugge II |
| 2025 24 September | | Second Division | RWDM Brussels | 1 - 2 | Kortrijk |
| 2025 14 September | | Second Division | RWDM Brussels | 5 - 0 | Seraing United |
Last 5 Anderlecht Away Matches
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| 2025 24 October | | Pro League | Sporting Charleroi | 1 - 0 | Anderlecht |
| 2025 19 October | | Pro League | Sint-Truiden | 2 - 2 | Anderlecht |
| 2025 26 September | | Pro League | OH Leuven | 1 - 1 | Anderlecht |
| 2025 31 August | | Pro League | Union Saint-Gilloise | 2 - 0 | Anderlecht |
| 2025 28 August | | Europa Conference League | AEK Athens | 2 - 0 | Anderlecht |
Last 5 FC Brussels Away Matches
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| 2025 29 October | | Cup | Genk | 3 - 0 | RWDM Brussels |
| 2025 25 October | | Second Division | Liege | 4 - 3 | RWDM Brussels |
| 2025 4 October | | Second Division | AS Eupen | 2 - 2 | RWDM Brussels |
| 2025 28 September | | Second Division | KAA Gent II | 0 - 2 | RWDM Brussels |
| 2025 19 September | | Second Division | Lierse Kempenzonen | 2 - 0 | RWDM Brussels |