Unitedís new left-back Alex Telles makes his Premier League debut. He is returning after Covid-19, as are Branislav Ivanovic and Matheus Pereira in the West Brom side. But West Brom have lost two more players to Covid, with the captain Jake Livermore and Kieran Gibbs unavailable.
Donny van de Beek is still only on the bench for United, while Paul Pogba isnít in the squad. He has an ankle injury.
Manchester United (4-2-3-1) de Gea; Wan-Bissaka, Lindelof, Maguire, Telles; Fred, Matic; Mata, Fernandes, Rashford; Martial.
Substitutes: Henderson, Tuanzebe, Williams, James, McTominay, van de Beek, Cavani.
West Bromwich Albion (5-4-1) Johnstone; Furlong, Ajayi, Ivanovic, Bartley, Townsend; Pereira, Sawyers, Gallagher, Diangana; Grant.
Substitutes: Button, OíShea, Phillips, Harper, Krovinovic, Robson-Kanu, Robinson.
Referee David Coote.